Dictyostelium Mutants

Phenotypes for Dictyostelium mutants

View other mutant types: All mutant strains - Null - Overexpression - Multiple - Other - Developmental

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Systematic Name Strain Descriptor Associated gene(s) Phenotypes
DBS02354121C7gp130decreased cell-substrate adhesion | delayed development | increased growth rate
DBS023541324EH6racEabolished cytokinesis
DBS02354142F5gp130decreased cell-substrate adhesion | delayed development | increased growth rate
DBS02386015NT-5NTmultiple tips in culminant | delayed tip formation | multiple tips in mound
DBS0235584CF45-1-cf45-1increased aggregate size | decreased cell motility | increased cell-cell adhesion | decreased aggregate size | increased intracellular glucose level
DBS0235585CF50-cf50-1increased aggregate size | increased gene expression | increased cell-cell adhesion | decreased extracellular counting factor component(s) level | increased protein level
DBS0235594CHE10cbpCdecreased slug migration | precocious aggregation | decreased aggregate size | decreased fruiting body size | delayed culmination
DBS0235595CHI2cbpCincreased slug migration
DBS0235612CMFR1-cmfBdecreased gene expression | abolished aggregation
DBS0235596ChLim-ChLimincreased growth rate | increased phagocytosis
DBS0252637DAip1-aip1decreased pinocytosis | delayed cytokinesis | decreased growth rate | decreased phagocytosis
DBS0235659DD3-3-DD3-3decreased gene expression | precocious aggregation
DBS0236049DDB_G0268012-DDB_G0268012wild type
DBS0236046DDB_G0268158-DDB_G0268158wild type
DBS0236039DDB_G0268678-DDB_G0268678wild type
DG1007DDB_G0269232-DDB_G0269232abolished culmination
DBS0236025DDB_G0270366-DDB_G0270366wild type
DBS0236026DDB_G0270368-DDB_G0270368wild type
DBS0236036DDB_G0270744-DDB_G0270744wild type
DBS0266514DDB_G0271714-/ DDB_G0271824-/ DDB_G0271716-/ DDB_G0271718-/ DDB_G0271822-/ DDB_G0271712-/ DDB_G0295685-/ DDB_G0271818-DDB_G0271712 | DDB_G0271714 | DDB_G0271716 | DDB_G0271718 | DDB_G0271818 | DDB_G0271822 | DDB_G0271824 | DDB_G0295685wild type
DBS0266513DDB_G0272654-/ DDB_G0273021-/ DDB_G0273023-/ DDB_G0272656-/ DDB_G0272658-/ DDB_G0272927-/ DDB_G0273025-DDB_G0272654 | DDB_G0272656 | DDB_G0272658 | DDB_G0272927 | DDB_G0273021 | DDB_G0273023 | DDB_G0273025wild type
DBS0236043DDB_G0276221-DDB_G0276221wild type
DBS0236042DDB_G0276689-DDB_G0276689wild type
DBS0236041DDB_G0277179-DDB_G0277179wild type
DBS0236045DDB_G0277575-DDB_G0277575wild type
DBS0236044DDB_G0278315-DDB_G0278315wild type
DBS0236038DDB_G0279005-DDB_G0279005wild type
DBS0236032DDB_G0279163-DDB_G0279163wild type
DBS0236033DDB_G0279163-DDB_G0279163wild type
DBS0236028DDB_G0279609-DDB_G0279609wild type
DBS0236029DDB_G0279609-DDB_G0279609wild type
DBS0236035DDB_G0280481-DDB_G0280481wild type
DBS0236019DDB_G0281735-DDB_G0281735wild type
DBS0236020DDB_G0281735-DDB_G0281735wild type
DBS0236027DDB_G0290225-DDB_G0290225wild type
DG1003DDB_G0291992-DDB_G0291992aberrant culminant morphology
DBS0236037DDB_G0292186-DDB_G0292186wild type
DBS0236023DDB_G0293116-DDB_G0293116wild type
DBS0236024DDB_G0293116-DDB_G0293116wild type
DBS0236030DDB_G0293762-DDB_G0293762wild type
DG1039DG1039-DDB_G0284037aberrant fruiting body morphology
DG1040DG1040-DDB_G0276029aberrant fruiting body morphology
DG1041DG1041-DDB_G0269126aberrant fruiting body morphology
DG1054DG1054-DDB_G0277719aberrant fruiting body morphology
DG1060DG1060-DDB_G0281953aberrant fruiting body morphology
DG1062DG1062-DDB_G0286351aberrant fruiting body morphology
DG1074DG1074-DDB_G0272108aberrant fruiting body morphology
DG1080DG1080-DDB_G0281559aberrant fruiting body morphology
DG1091DG1091-DG1091decreased fruiting body size
DG1098DG1098-DG1098decreased fruiting body size
DG1104DG1104-DDB_G0283535abolished aggregation
DG1105DG1105-DG1105abolished aggregation
DG1106DG1106-DG1106abolished aggregation
DG1110DG1110-DDB_G0269128aberrant fruiting body morphology
DG1112DG1112-DG1112decreased stalk width
DG1113DG1113-DG1113increased stalk length
DG1122DG1122-DG1122aberrant fruiting body morphology
DG1124DG1124-DG1124development arrests at loose aggregate stage
DG2033DG2033-DG2033development arrests at mound stage
DG2044DG2044-DG2044development arrests at loose aggregate stage
DBS0266700Dd5P1-Dd5P1wild type
DBS0266705Dd5P1-/ Dd5P2-Dd5P1 | Dd5P2wild type
DBS0266704Dd5P1-/ Dd5P3-Dd5P1 | Dd5P3wild type
DBS0235660Dd5P2-Dd5P2wild type | increased basal F-actin level
DBS0266703Dd5P2-/ Dd5P3-Dd5P2 | Dd5P3wild type
DBS0266702Dd5P3-Dd5P3wild type
DBS0266692Dd5P4-Dd5P4decreased growth rate | decreased phagocytosis | decreased engulfment during phagocytosis | multiple tips in mound
DBS0266693Dd5P4-/ [act15]: Dd5P4Dd5P4wild type
DBS0266719Dd5P4-/ [act15]: Dd5P4: GFPDd5P4wild type
DBS0266695Dd5P4-/ [act15]: GAP5P4Dd5P4decreased growth rate | multiple tips in mound
DBS0266720Dd5P4-/ [act15]: Hs-OCRLDd5P4decreased phagocytosis
DBS0266721Dd5P4-/ [act15]: Hs-OCRL(D422A)Dd5P4decreased phagocytosis
DBS0266694Dd5P4-/ [act15]: cat5P4Dd5P4decreased growth rate | multiple tips in mound
DBS0235940EB1-eb1aberrant mitosis
CW0391FLAG-VwkAvwkAdecreased growth rate in suspension | increased myosin II assembly | aberrant cytokinesis | development arrests at mound stage | increased protein level
DBS0236015GEG04K11 (tmcB- in KAX3)tmcBsmall macrocysts | increased number of peripheral cells during sexual reproduction | aberrant aggregation during macrocyst formation
DBS0236016GEG04V12 (tmcB- in V12)tmcBsmall macrocysts | increased number of peripheral cells during sexual reproduction | aberrant aggregation during macrocyst formation
DBS0236017GEG10K23 (tmcC- in KAX3)tmcCincreased number of peripheral cells during sexual reproduction | aberrant aggregation during macrocyst formation
DBS0236018GEG10V03 (tmcC- in V12)tmcCincreased number of peripheral cells during sexual reproduction | aberrant aggregation during macrocyst formation
CW0368GFP-VwkAvwkAdecreased growth rate in suspension | aberrant cytokinesis
DBS0302603GFP: disgorgin/ disgorgin-DDB_G0280955wild type
DBS0266872GFP: pcnapcnawild type
DBS0302615GFP: phgA(1-274: 283-438)/ phgA-phgAaberrant response to hypo-osmotic stress
DBS0302614GFP: phgA/ phgA-phgAwild type
DBS0236084GP138A-/ GP138B-/ GP138C-/ GP138D-cfrA | cfrB | cfrC | cfrDdecreased gene expression
DBS0236085GP138C-cfrCwild type
HL250HL250gmddecreased growth rate in bacterial suspension
DBS0236358HR42fbxAabolished culmination | decreased sporulation
HTY506HTY506pkaRaberrant spore morphology | decreased spore viability | decreased phosphorylation of actin | increased sporulation | precocious development | aberrant fruiting body morphology
DBS0236444JH.DcbfAabolished gene expression | decreased gene expression | decreased growth rate | increased pinocytosis | increased cell size | decreased fruiting body size | decreased stalk width | abolished aggregation | increased phagocytosis
DBS0236716PAKc-pakCdecreased chemotaxis rate | decreased lateral pseudopod suppression
DBS0236779PIPkinA-pik6decreased gene expression | abolished aggregation
DBS0236783PKAcat-pkaCabolished aggregation
DBS0236840R7nosAdevelopment arrests at mound stage
DBS0266873RFP: pcnapcnawild type
DBS0236900RIP3ripAdecreased cell polarity | abolished activation of adenylate cyclase | decreased chemotaxis rate | abolished aggregation | decreased myosin II assembly
DBS0236982TL114csbAdecreased cell-cell adhesion | abolished aggregation
DBS0236996TL26cotBaberrant spore coat morphology
DBS0264065V00262dagAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264066V00347DDB_G0281917abolished culmination
DBS0264073V10108DDB_G0292162abolished slug migration | aberrant vegetative growth | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264075V10113yakAabolished slug migration | aberrant vegetative growth | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation | aberrant cAMP wave formation
DBS0264078V10116tipBaberrant aggregation | abolished slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264079V10117DDB_G0285083aberrant slug migration | abolished culmination
DBS0264081V10119DDB_G0292194wild type
DBS0264083V10121DDB_G0269332wild type
DBS0264087V10125DDB_G0293302aberrant slug migration | aberrant cAMP wave formation
DBS0264088V10126tipCaberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264089V10127DG1037abolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation | aberrant cAMP wave formation
DBS0264098V10136DDB_G0293590wild type | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264099V10137yelAaberrant aggregation | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0264100V10138tipCwild type
DBS0264106V10144comHaberrant aggregation | abolished slug migration | abolished culmination
DBS0264108V10146yakAabolished slug migration | aberrant vegetative growth | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264109V10147tipAaberrant streaming | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264112V10150swp1wild type
DBS0264116V10155DDB_G0282093aberrant streaming | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant slug migration | abolished streaming | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264118V10157usp12aberrant streaming | aberrant culmination | aberrant slug migration | abolished culmination
DBS0264125V10164comEaberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished culmination
DBS0264126V10165comDaberrant aggregation | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0264128V10167DG1098wild type | aberrant cAMP wave formation
DBS0264129V10168prsCwild type | aberrant slug migration
DBS0264131V10170DDB_G0283015aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264135V10174DDB_G0288581aberrant streaming | aberrant vegetative growth | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264145V10185abcA5wild type | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0264150V10190yelAaberrant aggregation | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0264151V10191sfbAaberrant culmination | aberrant slug migration | abolished culmination
DBS0264152V10192tipDaberrant aggregation | abolished slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264154V10194modAaberrant culmination | aberrant slug migration
DBS0264155V10195migAaberrant streaming | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264157V10197yelAabolished slug migration | aberrant culmination | aberrant slug migration
DBS0264158V10198splAaberrant streaming | aberrant aggregation | aberrant culmination | aberrant cAMP wave formation
DBS0264159V10199DG1037aberrant streaming | abolished slug migration | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264160V10200DDB_G0289377aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264161V10201rgaAaberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264163V10203modAwild type | aberrant vegetative growth | aberrant culmination
DBS0264164V10204DG1124aberrant streaming | aberrant aggregation | aberrant cAMP wave formation
DBS0264166V10206wimAwild type
DBS0264169V10209dcsAabolished culmination
DBS0264170V10210mkpAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264171V10211migAaberrant streaming | aberrant culmination | aberrant cAMP wave formation
DBS0264172V10212tipCaberrant aggregation | abolished slug migration | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0264173V10213DG1098aberrant streaming | aberrant cAMP wave formation
DBS0264175V10215cbfBwild type
DBS0264176V10216DDB_G0292884wild type | aberrant vegetative growth
DBS0264180V10220potAwild type
DBS0264181V10221tipDaberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264182V10222ctaAwild type
DBS0264183V10223erkAaberrant streaming | aberrant cAMP wave formation
DBS0264184V10224DG1091aberrant cAMP wave formation
DBS0264185V10225acrAaberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264186V10226ggtAaberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished aggregation | abolished culmination
DBS0264187V10227piaAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264188V10228comGaberrant aggregation | aberrant streaming | abolished slug migration | aberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264189V10229dcsAabolished culmination | aberrant cAMP wave formation
DBS0264190V10230ctrAaberrant aggregation | aberrant culmination | aberrant slug migration
DBS0264193V10233piaAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264195V10235DDB_G0285985wild type
DBS0264196V10236DDB_G0270872_psaberrant streaming
DBS0264197V10237DDB_G0278621wild type
DBS0264198V10238DDB_G0269128aberrant culmination | aberrant slug migration
DBS0264199V10239kif12wild type | aberrant culmination
DBS0264201V10241lvsBaberrant culmination
DBS0264202V10242tagBaberrant aggregation | abolished slug migration | abolished culmination
DBS0264204V10244gbfAaberrant culmination | aberrant slug migration
DBS0264205V10245gefAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264206V10246dicBaberrant streaming | aberrant cAMP wave formation
DBS0264207V10247yelAaberrant aggregation | abolished slug migration | aberrant culmination | abolished culmination | aberrant cAMP wave formation
DBS0264212V10252tagBaberrant aggregation | abolished slug migration | abolished culmination
DBS0264216V10256DDB_G0293302aberrant streaming | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0264218V10258rdeAaberrant streaming | aberrant aggregation | abolished slug migration | aberrant culmination | abolished culmination | aberrant cAMP wave formation
DBS0264220V10260gacTaberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264224V10264DDB_G0282787_RTEaberrant streaming | aberrant aggregation | wild type | abolished slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264225V10265lvsDaberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0264227V10267DDB_G0292260_RTEaberrant streaming | aberrant aggregation
DBS0264228V10268dhkAaberrant streaming | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264229V10269helCwild type | aberrant culmination | aberrant slug migration | abolished culmination
DBS0264230V10270mekAaberrant streaming | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0264231V10271lvsBabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264232V10272modAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264233V10273DDB_G0283535wild type | aberrant vegetative growth
DBS0264234V10274DG1113aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0264235V10275DG1122aberrant streaming | wild type | abolished slug migration | aberrant vegetative growth | abolished streaming | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264236V10276DDB_G0270654wild type
DBS0264237V10277lvsEaberrant cAMP wave formation
DBS0264238V10278modAaberrant streaming | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264240V10280mekAaberrant streaming | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264241V10281DDB_G0268266aberrant slug migration | aberrant cAMP wave formation
DBS0264242V10282phdAaberrant streaming | abolished slug migration | aberrant culmination
DBS0264245V10285DG1105abolished slug migration | aberrant vegetative growth | abolished streaming | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264246V10286amdAwild type | aberrant culmination
DBS0264247V10287helCwild type | aberrant culmination | aberrant slug migration
DBS0264251V10300DDB_G0278333aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264268V10321adprt1Bwild type | aberrant cAMP wave formation
DBS0264269V10322roco5aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264272V10326DG1113wild type | aberrant cAMP wave formation
DBS0264275V10330DDB_G0282121wild type
DBS0264278V10342DDB_G0279727wild type
DBS0264281V10356DDB_G0275747aberrant slug migration
DBS0264283V10363msh5wild type
DBS0264284V10367DDB_G0282463aberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264287V10431kcnma1wild type | aberrant culmination | aberrant slug migration
DBS0264288V10432DDB_G0291103wild type
DBS0264290V10435gefLabolished slug migration | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264292V10438DDB_G0275671wild type
DBS0264295V10442pks3wild type
DBS0264297V10445DDB_G0290835aberrant slug migration
DBS0264303V10460abcC9aberrant slug migration
DBS0264316V10483yod1aberrant aggregation | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264318V10490gefVaberrant culmination | aberrant cAMP wave formation
DBS0264319V10492med23aberrant culmination | aberrant cAMP wave formation
DBS0264320V10495DDB_G0269128wild type | aberrant culmination | aberrant slug migration
DBS0264324V10514adprt3aberrant streaming | aberrant cAMP wave formation
DBS0264326V10519DDB_G0290575wild type
DBS0264330V10529cyp508B1aberrant streaming | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264331V10530DDB_G0270344wild type | aberrant slug migration | aberrant cAMP wave formation
DBS0264334V10534DDB_G0291812wild type | aberrant culmination
DBS0264335V10535DDB_G0277165aberrant streaming | aberrant cAMP wave formation
DBS0264337V10537gbpCaberrant streaming | wild type | abolished streaming | aberrant cAMP wave formation
DBS0264347V10567dagAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264349V10570DDB_G0281115aberrant streaming | wild type | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264356V10588dhkCaberrant streaming | wild type | aberrant cAMP wave formation
DBS0264373V10633gtaGabolished slug migration | aberrant culmination | aberrant slug migration | abolished culmination
DBS0264377V10642fscDwild type
DBS0264384V10670taf2wild type
DBS0264390V10682clcDabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation | aberrant cAMP wave formation
DBS0264425V11033nfaAaberrant streaming | aberrant aggregation | wild type | aberrant cAMP wave formation
DBS0264432V11040DDB_G0274177abolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264438V11047DDB_G0269296wild type
DBS0264439V11048xrcc4wild type
DBS0264444V11053dscA-1 | dscA-2wild type | aberrant vegetative growth
DBS0264446V11055ku80aberrant vegetative growth | aberrant culmination
DBS0264464V11075cinCwild type | aberrant culmination
DBS0264480V11092cnrOwild type
DBS0264489V11105DDB_G0270350_psaberrant streaming | wild type | aberrant cAMP wave formation
DBS0264512V11128DDB_G0278945aberrant streaming | aberrant vegetative growth | aberrant cAMP wave formation
DBS0264575V30069DDB_G0284619aberrant streaming | aberrant cAMP wave formation
DBS0264607V30110alg9wild type | aberrant vegetative growth | aberrant cAMP wave formation
DBS0264630V30133DDB_G0272953aberrant streaming | wild type | aberrant cAMP wave formation
DBS0264634V30137DDB_G0289529wild type
DBS0264662V30165alg9aberrant streaming | wild type | aberrant culmination | aberrant cAMP wave formation
DBS0264668V30171DDB_G0285261aberrant streaming | wild type | aberrant vegetative growth | aberrant cAMP wave formation
DBS0264677V30180gpaFaberrant streaming | wild type | aberrant cAMP wave formation
DBS0264684V30188DDB_G0287723aberrant streaming | wild type | aberrant cAMP wave formation
DBS0264687V30191DDB_G0288219wild type | aberrant vegetative growth
DBS0264700V30213act9wild type | aberrant culmination
DBS0264715V30229dhx35wild type | aberrant cAMP wave formation
DBS0264716V30230regAaberrant streaming | aberrant aggregation | abolished slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264731V30245DDB_G0279461wild type | aberrant culmination
DBS0264749V30264DDB_G0273651wild type
DBS0264752V30267DDB_G0283759wild type
DBS0264756V30271ncapGawild type
DBS0264763V30278DDB_G0286963wild type
DBS0264765V30280ppt1wild type
DBS0264768V30283DDB_G0270872_pswild type
DBS0264770V30285DDB_G0293762wild type | aberrant vegetative growth
DBS0264773V30288DDB_G0293300aberrant streaming | wild type | aberrant cAMP wave formation
DBS0264777V30292glpDwild type
DBS0264781V30296DDB_G0270212wild type
DBS0264785V30303pakEaberrant cAMP wave formation
DBS0264823V30341frmBaberrant streaming | wild type | aberrant culmination
DBS0264832V30350DDB_G0284059wild type
DBS0264835V30353DDB_G0282471wild type
DBS0264853V30371abpCaberrant aggregation | abolished slug migration | aberrant culmination | abolished culmination
DBS0264905V30427DDB_G0291926aberrant streaming | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264910V30432malAwild type
DBS0264922V30446DDB_G0269430wild type
DBS0264924V30448DDB_G0269680wild type | aberrant cAMP wave formation
DBS0264941V30466dtfAwild type | aberrant cAMP wave formation
DBS0264992V30522DDB_G0288007aberrant streaming | wild type | aberrant cAMP wave formation
DBS0264994V30524prmt5aberrant streaming | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0265002V30532lvsAwild type | abolished slug migration | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0265017V30547DDB_G0279105aberrant streaming | wild type | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0265029V30561DDB_G0277355wild type | aberrant culmination
DBS0265045V30578DDB_G0277165aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0265049V30582DDB_G0291722wild type
DBS0265064V30604DDB_G0279461aberrant streaming | abolished slug migration | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0265066V30606adkBwild type
DBS0265099V30642tipCaberrant aggregation | abolished slug migration | abolished culmination | aberrant cAMP wave formation
DBS0265126V30673dicBaberrant aggregation | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0265140V30688DDB_G0279727wild type | aberrant culmination
DBS0265170V30724cnrKwild type
DBS0265206V30766rhgAwild type
DBS0265226V30789itpawild type
DBS0265231V30794tpsAwild type
DBS0265247V30814adprt1Bwild type
DBS0265279V30846DDB_G0286091wild type
DBS0265286V30853DDB_G0292058wild type
DBS0265296V30863DDB_G0269128wild type
DBS0265302V30869DDB_G0292454wild type | aberrant vegetative growth
DBS0265303V30870gxcJJwild type | aberrant cAMP wave formation
DBS0265309V30876DDB_G0268248aberrant streaming | wild type | aberrant cAMP wave formation
DBS0265311V30879exoc2aberrant streaming | wild type | aberrant cAMP wave formation
DBS0265319V30887adcCwild type
DBS0265339V30912DDB_G0283821wild type | aberrant cAMP wave formation
DBS0265348V30921snpCwild type | aberrant culmination
DBS0265422V30995DDB_G0282959wild type
DBS0265466V31043DDB_G0275917aberrant aggregation | wild type | aberrant vegetative growth | aberrant slug migration | abolished culmination
DBS0265497V31075DDB_G0282985aberrant streaming | wild type | abolished slug migration | aberrant culmination | abolished aggregation | aberrant cAMP wave formation
DBS0265520V31102DDB_G0287865wild type
DBS0265529V31111vps13Eaberrant streaming | wild type | aberrant culmination | aberrant cAMP wave formation
DBS0265539V31121DDB_G0270912wild type | aberrant vegetative growth | aberrant cAMP wave formation
DBS0265567V31151DDB_G0275539wild type | aberrant vegetative growth | abolished culmination
DBS0265573V31157act9wild type
DBS0265588V31173ggtAaberrant streaming | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0265662V31255psiNaberrant streaming | wild type | aberrant culmination | aberrant cAMP wave formation
DBS0265688V31281DDB_G0286417aberrant streaming | wild type | aberrant culmination | aberrant cAMP wave formation
DBS0265701V31294DDB_G0268424wild type
DBS0265873V31480DDB_G0284177aberrant culmination
DBS0265890V31501DDB_G0282985wild type | aberrant culmination | aberrant cAMP wave formation
DBS0265908V31523tmem184Cwild type | aberrant culmination
DBS0265911V31528DDB_G0279945aberrant culmination
DBS0265938V31568rsc12aberrant culmination
DBS0265947V31583DDB_G0282943wild type
DBS0265992V31640DDB_G0274343wild type
DBS0266000V31649DDB_G0290383wild type | aberrant culmination
DBS0266021V31670DDB_G0281269wild type
DBS0266022V31671dhkAaberrant culmination | aberrant slug migration
DBS0266036V31685tipCaberrant streaming | aberrant aggregation | wild type | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0266084V31738dcsAwild type | aberrant culmination | abolished culmination
DBS0266088V31742dstAaberrant culmination | aberrant slug migration | abolished culmination
DBS0266089V31743DDB_G0273459aberrant streaming | aberrant aggregation | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0266098V31752oplahwild type | aberrant cAMP wave formation
DBS0266149V31807gpt1wild type | abolished growth | aberrant vegetative growth
DBS0266153V31811gpt1wild type | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0266190V31853chlAaberrant aggregation | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0266195V31858DDB_G0286341aberrant streaming | wild type | aberrant cAMP wave formation
DBS0266246V31916psiFwild type | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0266249V31919DDB_G0276251aberrant streaming | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0266253V31923DDB_G0268314wild type | aberrant culmination
DBS0266258V31928DDB_G0268314wild type
DBS0266271V31941manAaberrant streaming | aberrant aggregation | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0266299V31970DDB_G0280581aberrant streaming | wild type | aberrant cAMP wave formation
DBS0266309V31982DDB_G0286341aberrant streaming | wild type | abolished streaming | aberrant cAMP wave formation
DBS0266316V31989DDB_G0270342wild type | abolished slug migration | aberrant culmination | abolished streaming | aberrant cAMP wave formation
DBS0237041VatMprvatMdecreased phagocytosis | decreased growth rate | aberrant intracellular pH level | increased localization of protein to the cytoplasm
DBS0237044VatMpr/ [act15]: vatMvatMwild type
DBS0237042VatMpr/ [act15]: vatM: GFPvatMdecreased growth rate
DBS0237236[AS]: [tet]: trrAtrrAdecreased growth rate | delayed development | abolished aggregation
DBS0237228[AS]GP138A/ [AS]GP138BcfrA | cfrBdecreased sexual fusion
DBS0304456[AS]alrA/ gcsA-alrA | gcsAdecreased growth rate in suspension | cell cycle arrest
DBS0237273[AS]calAcalAabolished cytokinesis
DBS0237222[AS]cf60cf60increased aggregate size | decreased number of aggregates
DBS0237223[AS]chcAchcAdecreased pinocytosis | delayed response to hypo-osmotic stress | decreased number of vacuoles | aberrant vacuole organization and biogenesis | abolished aggregation | decreased cell size
DBS0237224[AS]cmfAcmfAabolished aggregation
DBS0237225[AS]cupBcupBabolished aggregation
DBS0237226[AS]dia1dia1decreased gene expression | precocious aggregation
DBS0238235[AS]dutAdutAwild type
DBS0237229[AS]gpaAgpaAwild type
HPF414[AS]hspAhspAdecreased growth rate | aberrant fruiting body morphology
DBS0238749[AS]hspA/ snfAhspA | snfAwild type
DBS0252819[AS]hssAhssAwild type
DBS0237230[AS]ino1ino1abolished growth
DBS0304425[AS]mppA1mppA1delayed development
DBS0304424[AS]mppBmppBincreased gene expression
DBS0236725[AS]patApatAdecreased growth rate under Ca2+ stress
DBS0237504[AS]pikEpikEaberrant stalk morphogenesis | decreased growth rate
DBS0237231[AS]ppiAppiAincreased stalk length
DBS0237232[AS]proAproAwild type
DBS0236827[AS]proA/ proB-proA | proBincreased basal F-actin level | abolished growth | development arrests at slug stage | aberrant cytokinesis | decreased cell motility
DBS0238036[AS]proA/ proB-/ [act15]: proAproA | proBwild type
DBS0238037[AS]proA/ proB-/ [act15]: proBproA | proBwild type
DBS0238035[AS]proA/ proB-/ [unk]: FLAG: proCproA | proB | proCwild type
DBS0236851[AS]rapArapAdecreased pinocytosis | aberrant response to hyperosmotic stress | aberrant osmosensory signaling pathway | decreased phagocytosis | inviable | increased basal phosphorylated actin level
DBS0236904[AS]rps4mrps4delayed aggregation | aberrant fruiting body morphology
DBS0237234[AS]smlAsmlAdecreased fruiting body size
DBS0238748[AS]snfAsnfAdecreased number of mitochondria | aberrant mitochondrion organization and biogenesis | decreased intracellular ATP level | increased growth rate | decreased fruiting body size
DBS0304498[AS]sslA1sslA1decreased fruiting body size
DBS0237235[AS]tcp1tcp1decreased growth rate | development arrests at mound stage | aberrant fruiting body morphology
DBS0306101[AS]vatPvatPdecreased growth rate | decreased extracellular Ca2+ uptake
DBS0306102[AS]vatPvatPdecreased extracellular Ca2+ uptake | decreased growth rate | delayed development
DBS0266892[KD]gtaCgtaCabolished stalk cell differentiation
DBS0266893[KD]gtaC/ [act15]: GFP: gtaCgtaCwild type
DBS0237276[OE]: GFP: gxcAgxcAabolished aggregation
DBS0237279[OE]: HA: rab21(Q66L)rab21aberrant cytoskeleton organisation | decreased phagocytosis
DBS0237274[OE]: chlimChLimincreased basal F-actin level | decreased phagocytosis | decreased growth rate
DBS0302602[OE]: disgorgin(Delta-Fbox)/ disgorgin-DDB_G0280955wild type
DBS0302601[OE]: disgorgin(Q551A)/ disgorgin-DDB_G0280955aberrant contractile vacuole organization and biogenesis
DBS0302600[OE]: disgorgin(R515A)/ disgorgin-DDB_G0280955aberrant contractile vacuole organization and biogenesis
DBS0302599[OE]: disgorgin/ disgorgin-DDB_G0280955wild type
DBS0302610[OE]: disgorgin/ phgA-DDB_G0280955 | phgAaberrant contractile vacuole organization and biogenesis
DBS0237275[OE]: gbfAgbfAprecocious gene expression
DBS0237277[OE]: gpaDgpaDaberrant fruiting body morphology | decreased sporulation
JH258[OE]: gpaEgpaEprecocious tip formation | precocious gene expression
DBS0348921[OE]: ipkA1ipkA1aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression
DBS0348922[OE]: itpk1itpk1aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression
DBS0237281[OE]: limFlimFincreased basal F-actin level | increased phagocytosis
DBS0237282[OE]: pakCpakCdecreased cell motility
DBS0302611[OE]: phgA/ disgorgin-DDB_G0280955 | phgAaberrant contractile vacuole organization and biogenesis
DBS0237283[OE]: rasB(G12T)rasBaberrant cytokinesis
DBS0302685[OE]: sgcA(1-2000)(N1106A): GFP/ gca-/ sgcA-gcA | sgcAdecreased chemotaxis rate
DBS0302683[OE]: sgcA(878-2843)(N1106A): GFP/ gca-/ sgcA-gcA | sgcAdecreased chemotaxis rate
DBS0302681[OE]: sgcA(878-2843): GFP/ sgcA-gcA | sgcAdecreased chemotaxis rate
DBS0302682[OE]: sgcA(N1106A): GFP/ gca-/ sgcA-gcA | sgcAaberrant streaming | increased lateral pseudopod formation | decreased chemotaxis rate
DBS0302684[OE]: sgcA: GFP/ gca-/ sgcA-gcA | sgcAincreased lateral pseudopod formation | decreased chemotaxis rate
DBS0237284[OE]GFP: gxcA(1-750: 764-1217)gxcAdevelopment arrests at loose aggregate stage
DBS0237285[OE]GFP: gxcA(1-750: 764-984)gxcAdevelopment arrests at loose aggregate stage
DBS0266621[OE]mipp1mipp1aberrant inositol phosphate metabolic process | aberrant gene expression | increased response to lithium
DBS0237299[RNAi]DDB_G0270366DDB_G0270366wild type
DBS0237300[RNAi]DDB_G0270368DDB_G0270368wild type
DBS0237301[RNAi]DDB_G0271700DDB_G0271700wild type
DBS0237304[RNAi]DDB_G0273449DDB_G0273449 | DDB_G0273577wild type
DBS0237303[RNAi]DDB_G0279609DDB_G0279609wild type
DBS0237306[RNAi]DDB_G0290063DDB_G0290063wild type
DBS0237302[RNAi]DDB_G0290225DDB_G0290225wild type
DBS0237298[RNAi]DDB_G0293116DDB_G0293116wild type
DBS0237305[RNAi]DDB_G0293762DDB_G0293762wild type
DBS0237294[RNAi]DidioMp05DidioMp05wild type
DBS0235409[RNAi]cnbAcnbAmultiple tips in culminant | decreased gene expression | aberrant stalk cell differentiation | decreased stalk length
DBS0349787[RNAi]ctnnActnnAaberrant protein secretion | aberrant tip formation | aberrant Golgi localization | abolished stalk formation | aberrant centrosome localization | abolished culmination | abolished cell polarity | aberrant protein localization
DBS0237537[RNAi]enlAenlAdecreased cell-substrate adhesion | aberrant cytokinesis
DBS0237295[RNAi]fimAfimAwild type
DBS0237308[RNAi]gmsAgmsAdecreased sexual fusion
DBS0237309[RNAi]gsrgsrprecocious culmination | decreased sorting to prestalk region | precocious gene expression
DBS0252820[RNAi]hssAhssAwild type
DBS0237307[RNAi]kctd9kctd9wild type
DBS0237310[RNAi]lipAlipAwild type
DBS0237296[RNAi]pks16pks16wild type
DBS0237297[RNAi]psiMpsiMwild type
DBS0237311[RNAi]racF2racF2abolished growth in suspension
DBS0237312[RNAi]rasZrasZwild type
DBS0238734[RNAi]sdhAsdhAabolished aggregation | decreased phototaxis
DBS0304564[RNAi]sun1sun1aberrant nucleus morphology | increased cell size
DBS0237313[RNAi]tmcBtmcBaberrant macrocyst differentiation
DBS0237314[RNAi]tmcCtmcCaberrant macrocyst differentiation
DBS0237315[RNAi]trap1trap1decreased gene expression | delayed development
DBS0237818[RNAi]wipAwipAdelayed pseudopod formation | decreased F-actin polymerization at the leading edge | decreased chemotaxis to cAMP | decreased filopodium formation
DBS0349845[act15]: 7xHis: myoK: Ty1myoKaberrant cortical actin cytoskeleton stabilization | aberrant engulfment during phagocytosis | aberrant cell morphology
DBS0237100[act15]: CFP: racC(G15V)racCincreased basal F-actin level
DBS0237101[act15]: CFP: racC(T20N)racCabolished chemotaxis | aberrant cytokinesis | decreased basal F-actin level
DBS0266512[act15]: DDB_G0272656DDB_G0272656wild type
DBS0238107[act15]: FLAG: ppp4Cppp4cwild type
DBS0238108[act15]: FLAG: ppp4C(H113Q)ppp4cdevelopment arrests at mound stage | delayed development
DBS0237110[act15]: GFP(S65T)-racGracGincreased filopodium formation | decreased chemoattractant-mediated F-actin polymerization | decreased cell motility | increased phagocytosis
DBS0304572[act15]: GFP: abpD(1441-1736)abpDabolished localization of a protein to the nuclear envelope
DBS0304571[act15]: GFP: abpD(1441-1738)abpDabolished localization of a protein to the nuclear envelope
DBS0304573[act15]: GFP: abpD(1441-1738,1737P/ A)abpDabolished localization of a protein to the nuclear envelope
DBS0237114[act15]: GFP: abpE(413-481)abpE-1 | abpE-2increased lateral pseudopod formation
DBS0237116[act15]: GFP: act15act15abolished cytokinesis | decreased cell motility | aberrant cell morphology
DBS0235662[act15]: GFP: forH(1-425)forHaberrant protein localization
DBS0304973[act15]: GFP: gefQ(173-651,818-1298)gefQincreased Ras guanyl-nucleotide exchange factor activity
DBS0304971[act15]: GFP: gefQ(683-833)gefQdecreased Ras guanyl-nucleotide exchange factor activity
DBS0304972[act15]: GFP: gefQ(910-1298)gefQaberrant cytokinesis | aberrant phototaxis
DBS0236070[act15]: GFP: hcpAhcpAdecreased growth rate in suspension | aberrant anaphase
DBS0236071[act15]: GFP: hcpBhcpBdecreased growth rate in suspension
DBS0237117[act15]: GFP: krsAkrsAdecreased slug migration
DBS0237118[act15]: GFP: limElimEaberrant cytokinesis
DBS0237120[act15]: GFP: nek2nek2increased number of microtubule-organizing centers | aberrant nucleus morphology
DBS0237121[act15]: GFP: numA(1-117: 168-340)numAaberrant cytokinesis
DBS0237122[act15]: GFP: pats1(2087-2351)pats1aberrant cytokinesis
DBS0237123[act15]: GFP: phg2(1-245)phg2decreased phagocytosis
DBS0237702[act15]: GFP: rac1Arac1Aincreased filopodium formation | increased membrane ruffling
DBS0237703[act15]: GFP: rac1Brac1Bincreased filopodium formation | increased membrane ruffling
DBS0237704[act15]: GFP: rac1Crac1Cincreased filopodium formation | increased membrane ruffling
DBS0237125[act15]: GFP: racG(1-168): racH(164-200)racG | racHincreased filopodium formation | decreased chemoattractant-mediated F-actin polymerization | decreased phagocytosis
DBS0237127[act15]: GFP: racHracHdecreased pinocytosis | decreased phagocytosis | decreased growth rate | aberrant cytokinesis | aberrant cell morphology
DBS0237128[act15]: GFP: racH(1-163): racG(167-201)racG | racHdecreased chemoattractant-mediated F-actin polymerization
DBS0237130[act15]: GFP: racH(M13V)racHincreased F-actin polymerization | aberrant cytokinesis | aberrant cell morphology
DBS0237132[act15]: GFP: racH(T18N)racHaberrant cytokinesis | aberrant cell morphology
DBS0237133[act15]: GFP: racH: gemA(630-658)gemA | racHdelayed cytokinesis
DBS0238392[act15]: GFP: rapArapAincreased cell-substrate adhesion
DBS0238393[act15]: GFP: rapA(G12V)rapAincreased cell-substrate adhesion
DBS0238394[act15]: GFP: rapA(S17N)rapAdecreased cell-substrate adhesion
DBS0237134[act15]: GFP: sbdssbdswild type
DBS0237135[act15]: GFP: sbdssbdswild type
DBS0304563[act15]: GFP: sun1(283-905)sun1increased number of centrosomes | increased cell size | aberrant nucleus morphology | aberrant perinuclear space | aberrant centrosome localization | aberrant sister chromosome segregation | decreased localization of a protein to the nuclear envelope
DBS0238111[act15]: HA: smkAsmkAdecreased cell polarity | delayed development | decreased fruiting body size | decreased chemotaxis to cAMP
DBS0237201[act15]: YFP: myoEmyoEdecreased pinocytosis | increased phagocytosis
DBS0237817[act15]: YFP: wipAwipAincreased filopodium formation | increased F-actin polymerization at the leading edge
DBS0237819[act15]: YFP: wipA(K36A)wipAincreased filopodium formation | increased F-actin polymerization at the leading edge
DBS0237821[act15]: YFP: wipA(K93A/ S95A)wipAincreased filopodium formation | increased F-actin polymerization at the leading edge
DBS0237227[act15]: [AS]dia2dia2decreased extracellular cAMP level | aberrant cAMP signaling during aggregation | abolished aggregation
DBS0304574[act15]: abpDabpDabolished localization of a protein to the nuclear envelope
DBS0237096[act15]: abpEabpE-1 | abpE-2aberrant aggregation | increased lateral pseudopod formation | decreased cell motility | delayed development | decreased fruiting body size
DBS0238086[act15]: atg1atg1wild type
DBS0238091[act15]: atg1(1-628)atg1wild type
DBS0238088[act15]: atg1(K36A)atg1abolished macroautophagy | increased number of autophagosomes | aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238090[act15]: atg1(K36A/ 1-628)atg1wild type
DBS0237097[act15]: cak1: myccak1-1 | cak1-2increased resistance to DNA-damaging agents
DBS0252737[act15]: carA(I104A)carA-1 | carA-2decreased cAMP binding
DBS0252732[act15]: carA(I104C)carA-1 | carA-2decreased MAP kinase activation
DBS0252740[act15]: carA(I104D)carA-1 | carA-2increased cAMP binding | delayed aggregation | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0252744[act15]: carA(I104E)carA-1 | carA-2increased cAMP binding | delayed aggregation | aberrant cAMP wave formation
DBS0252741[act15]: carA(I104F)carA-1 | carA-2increased cAMP binding | decreased MAP kinase activation
DBS0252738[act15]: carA(I104G)carA-1 | carA-2increased cAMP binding | decreased MAP kinase activation
DBS0252747[act15]: carA(I104H)carA-1 | carA-2development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252749[act15]: carA(I104K)carA-1 | carA-2increased cAMP binding | decreased MAP kinase activation | abolished aggregation | abolished cAMP wave formation
DBS0252739[act15]: carA(I104L)carA-1 | carA-2wild type
DBS0252742[act15]: carA(I104M)carA-1 | carA-2increased cAMP binding
DBS0252746[act15]: carA(I104N)carA-1 | carA-2development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252734[act15]: carA(I104P)carA-1 | carA-2decreased MAP kinase activation
DBS0252745[act15]: carA(I104Q)carA-1 | carA-2development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252750[act15]: carA(I104R)carA-1 | carA-2development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252743[act15]: carA(I104S)carA-1 | carA-2increased cAMP binding | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0252735[act15]: carA(I104T)carA-1 | carA-2increased cAMP binding | aberrant cAMP wave formation
DBS0252736[act15]: carA(I104V)carA-1 | carA-2wild type
DBS0252733[act15]: carA(I104W)carA-1 | carA-2increased cAMP binding
DBS0252748[act15]: carA(I104Y)carA-1 | carA-2development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0237098[act15]: cdk5(D144N)cdk5decreased pinocytosis | increased aggregate size | delayed aggregation | decreased phagocytosis | decreased growth rate | decreased extracellular counting factor component(s) level | increased extracellular counting factor component(s) level | decreased sporulation | increased intracellular counting factor component(s) level
DBS0237099[act15]: cf60cf60aberrant regulation of aggregate size | increased number of aggregates
DBS0302445[act15]: cfaDcfaDdecreased growth rate | aberrant fruiting body morphology
DBS0302656[act15]: cnrN/ cnrN-cnrNwild type
DBS0302658[act15]: cnrN/ smlA-cnrN | smlAdecreased fruiting body size
DBS0237102[act15]: cofAcofAincreased actin bundle formation | increased membrane ruffling | increased cell motility
DBS0237104[act15]: dagAdagAwild type
DBS0237105[act15]: dgkAdgkAdevelopment arrests at loose aggregate stage | decreased chemotaxis rate | decreased myosin II assembly
DBS0237106[act15]: dhkC(394-661)dhkCincreased slug migration
DBS0235716[act15]: dhkKdhkKprecocious aggregation | development arrests at mound stage
DBS0235705[act15]: dhkK(D1125N)dhkKaberrant cAMP signaling during aggregation | delayed development
DBS0235707[act15]: dhkK(H825Q)dhkKprecocious development | decreased fruiting body size
DBS0235709[act15]: dhkK(H825Q/ D1125N)dhkKaberrant slug migration | delayed culmination
DBS0237107[act15]: dng1dng1decreased growth rate | precocious aggregation | aberrant cAMP signaling during aggregation
DBS0237562[act15]: enlA(92-497)enlAdecreased cell-substrate adhesion
DBS0237108[act15]: fbxA: FLAGfbxAdecreased prespore cell differentiation
DBS0237109[act15]: fpsfpsincreased resistance to bisphosphonates
DBS0235979[act15]: fszA: GFPfszAincreased number of tubular mitochondria
DBS0237601[act15]: gbpDgbpDincreased Ras guanyl-nucleotide exchange factor activity | increased cell-substrate adhesion | decreased chemotaxis to cAMP | aberrant cell morphology
DBS0237136[act15]: gpaAgpaAincreased stalk length | aberrant cytokinesis | aberrant fruiting body morphology
DBS0237145[act15]: gpaGgpaGaberrant fruiting body morphology
DBS0237146[act15]: gpaHgpaHwild type
DBS0237147[act15]: gpaI(G38V): FLAGgpaIincreased aggregate size | delayed aggregation | decreased number of aggregates | aberrant fruiting body morphology
DBS0237148[act15]: gpaI(Q196L): FLAGgpaIincreased aggregate size | delayed aggregation | decreased number of aggregates | aberrant fruiting body morphology
DBS0237149[act15]: grxAgrxAdecreased gene expression | delayed culmination
DBS0237151[act15]: grxA(C21S)grxAwild type
DBS0237152[act15]: grxA/ [act15]: lacZgrxAincreased sorting to prestalk region
DBS0237153[act15]: gsrgsrincreased sorting to prestalk region | delayed culmination
DBS0252821[act15]: hssAhssAwild type
DBS0237203[act15]: mhkB: FLAGmhkBaberrant cytokinesis | decreased myosin II assembly
DBS0237157[act15]: mkkAmkkAdevelopment arrests at mound stage | delayed development
DBS0237158[act15]: mkkA(K199A)mkkAprecocious development | decreased sporulation
DBS0237159[act15]: mkkA{deltaWD40}mkkAdevelopment arrests at mound stage | delayed development | aberrant fruiting body morphology
DBS0237160[act15]: mtaA(1-813)/ [dscB]tubA: GFPmtaAaberrant microtubule cytoskeleton organization
DBS0237162[act15]: myc-cdk8cdk8multiple tips
DBS0266839[act15]: myc: ptpΔ(3C649S)ptpCaberrant localization of protein to the nucleus | increased protein tyrosine phosphorylation
DBS0266837[act15]: myc: ptpCptpCaberrant signal transduction during aggregation | aberrant response to hyperosmotic stress | aberrant protein localization
DBS0266838[act15]: myc: ptpC(C649S)ptpCaberrant localization of protein to the nucleus | increased protein tyrosine phosphorylation
DBS0238398[act15]: myc: rapArapAincreased cell-substrate adhesion | decreased cell motility | aberrant cell morphology
DBS0238396[act15]: myc: rapA(G12V)rapAdelayed aggregation | increased cell-substrate adhesion | decreased cell motility
DBS0238397[act15]: myc: rapA(S17N)rapAdecreased cell-substrate adhesion
DBS0237167[act15]: myc: rckArckAdelayed development
DBS0237163[act15]: myc: rckA(C551A)rckAdelayed slug formation | decreased chemotaxis rate
DBS0237164[act15]: myc: rckA(E510G)rckAdelayed slug formation | decreased chemotaxis rate
DBS0237165[act15]: myc: rckA(E510G/ N511A)rckAdelayed slug formation | decreased chemotaxis rate
DBS0237166[act15]: myc: rckA(K867A)rckAdelayed slug formation | precocious aggregation | decreased chemotaxis rate
DBS0349847[act15]: myoK: MycmyoKdecreased phagocytosis
DBS0237175[act15]: myoMmyoMaberrant streaming | delayed development | increased pseudopod size
DBS0237178[act15]: myoM-MtailmyoMaberrant streaming | aberrant response to hyperosmotic stress | aberrant response to hypo-osmotic stress | decreased growth rate | delayed development | increased pseudopod size
DBS0237179[act15]: myr: rckArckAdelayed development | decreased chemotaxis rate
DBS0237180[act15]: nramp1: GFPnramp1increased iron ion transport | decreased infection rate by Legionella pneumophila
DBS0237182[act15]: pakApakAwild type
DBS0237183[act15]: pakA(K394A)pakAdevelopment arrests at mound stage | delayed development
DBS0237184[act15]: pakA[CA]pakAabolished aggregation
DBS0237185[act15]: pakA[G+K]pakAwild type
DBS0349855[act15]: pakB(1-337: 563-852)pakBdecreased phagocytosis
DBS0237188[act15]: pkaR(1-497)pkaRprecocious development | decreased intracellular cAMP level | decreased fruiting body size
DBS0235442[act15]: pldB: GFPpldBabolished aggregation
DBS0237192[act15]: rblArblAincreased cell cycle length
DBS0349793[act15]: sadA(921-S952)sadAdecreased cell-substrate adhesion
SA604[act15]: sgkA: FLAGsgkAincreased resistance to cisplatin | aberrant cytokinesis | increased resistance to carboplatin
DBS0304461[act15]: sir2Esir2Eincreased growth rate
DBS0238735[act15]: snfA(1-379): GFPsnfAincreased stalk width | increased intracellular ATP level | decreased growth rate | increased number of mitochondria | aberrant mitochondrion organization and biogenesis | decreased phototaxis | decreased stalk length
DBS0304457[act15]: sodA/ gcsA-gcsA | sodAwild type
DBS0237194[act15]: sodA: mycsodAdecreased gene expression | abolished aggregation
DBS0237195[act15]: spkA: FLAGspkA-1 | spkA-2aberrant aggregation | decreased cell polarity | aberrant F-actin organization | decreased chemotaxis rate
AK1209[act15]: tagA(1-890)tagAmultiple tips in mound
DBS0237198[act15]: torAtorAabolished growth
DBS0237199[act15]: trrAtrrAaberrant aggregation | decreased growth rate | decreased phagocytosis | delayed culmination
DBS0237200[act15]: vasPvasPincreased filopodium formation | increased basal F-actin level
DBS0237207[act6]: GFP: lvsA(1828- 3619)lvsAabolished cytokinesis
DBS0237209[act6]: GFP: mtaAmtaAincreased sensitivity to nocodazole | aberrant cytokinesis | increased number of microtubule-organizing centers | decreased length of astral microtubules | decreased number of astral microtubules
DBS0306243[act6]: GFP: sun1sun1increased number of centrosomes | aberrant nucleus morphology | aberrant sister chromosome segregation | aberrant centromere complex assembly | aberrant centrosome organization
DBS0306244[act6]: GFP: sun1(1-722)sun1increased number of centrosomes | aberrant nucleus morphology | aberrant sister chromosome segregation | aberrant centromere complex assembly | aberrant centrosome organization
DBS0238218[act6]: TAP: GFP: lvsBlvsBwild type
DBS0237204[act6]: canAcanAwild type
DBS0237205[act6]: dia1dia1delayed aggregation
DBS0236905[act6]: mrps4mrps4precocious aggregation
DBS0235444[act6]: myc: eppA(S250A)eppAdecreased growth rate | delayed development | decreased intracellular cAMP level
DBS0235445[act6]: myc: eppA(S325A)eppAdecreased growth rate
DBS0266836[act6]: ptpBptpBdelayed aggregation | decreased fruiting body size
DBS0237218[act6]: ptpCptpCincreased aggregate size | decreased growth rate
DBS0237219[act6]: ptpC(C649S)ptpCincreased aggregate size | decreased growth rate
DBS0304410[act6]: srsAsrsAincreased aggregate size | decreased gene expression | increased slug size | delayed aggregation | decreased sporulation | aberrant fruiting body morphology
DBS0237220[act6]: trap1trap1development arrests at loose aggregate stage | aberrant aggregation | abolished pinocytosis | increased gene expression | decreased gene expression | decreased growth rate
DBS0304460[act]: alrA/ gcsA-alrA | gcsAwild type
DBS0237221[arkA]: arkA: myc2arkAaberrant aggregation
HM2191[arpB]: arpB: GFParpBdecreased F-actin polymerization | decreased cell-substrate adhesion | decreased growth rate | decreased cell motility | increased bleb formation | decreased chemotaxis rate
DBS0237238[dscB]: GFP: rab8Arab8Awild type
DBS0237239[dscB]: GFP: rab8A(N128I)rab8Aincreased aggregate size | increased cell-cell adhesion | decreased fruiting body size
DBS0237240[dscB]: GFP: rab8A(Q74L)rab8Aaberrant cytoskeleton organisation | abolished aggregation
DBS0237241[dscB]: GFP: rab8Brab8Bincreased aggregate size
DBS0237242[dscB]: GFP: rab8B(Q74L)rab8Bincreased aggregate size
DBS0305081[dscB]: GFP: vamp7A(L35A)vamp7Aincreased localization of protein to the plasma membrane
DBS0237237[dscB]: cycB(106-436)cycBcell cycle arrest
DBS0237243[dscB]: myc: rac1Brac1Bdecreased growth rate in suspension | increased rate of endocytosis | aberrant cytokinesis | delayed development
DBS0237244[dscB]: myc: rac1B(G12V)rac1Bdecreased rate of endocytosis | decreased growth rate in suspension | abolished aggregation | aberrant cell morphology
DBS0237245[dscB]: myc: rac1B(Q61L)rac1Bdecreased rate of endocytosis | decreased growth rate in suspension | abolished aggregation | aberrant cell morphology
DBS0237246[dscB]: myc: rac1B(T17N)rac1Bdecreased rate of endocytosis | decreased growth rate in suspension | abolished aggregation
DBS0237247[dscB]: rapA(G12V)rapAaberrant osmosensory signaling pathway
DBS0237248[dscB]: rasG(G12T)rasGincreased cell-cell adhesion
DBS0304865[expl7]: expl7: GFPexpl7aberrant culminant morphology
DBS0237252[gpaA]: gpaA(G45V)gpaAdelayed development
DBS0237253[gpaA]: gpaA(Q206L)gpaAincreased basal disc size
DBS0237254[gpaB]: gpaB(Q208L)gpaBaberrant protein localization
DBS0237255[hairpin]dctdctaberrant cytokinesis
DBS0238412[inviable]arcB-arcBinviable
DBS0238407[inviable]arpB-arpBinviable
DBS0236484[pkaC]: pkaCpkaCdecreased intracellular cAMP level | precocious development | aberrant fruiting body morphology
DBS0237289[psmC1]: psmC1psmC1aberrant cytokinesis | delayed tip formation | delayed gene expression
DBS0237290[ptpA1]ptpA1ptpA1-1delayed aggregation | decreased growth rate | aberrant fruiting body morphology
DBS0237291[ptpB]ptpBptpBdecreased growth rate | development arrests at mound stage
DBS0237316[tet]: GFP(S65T): racG(G12V)racGincreased filopodium formation | decreased chemoattractant-mediated F-actin polymerization | increased phagocytosis | abolished chemotaxis to cAMP | decreased positive regulation of Rac GTPase activity
DBS0237317[tet]: GFP(S65T): racG(T17N)racGabolished chemoattractant-mediated F-actin polymerization | abolished chemotaxis to cAMP
DBS0238351[tet]: [RNAi]cinCcinCdecreased translation | precocious aggregation | decreased growth rate
DBS0237318[tet]: ptenptendecreased cell motility
DBS0237622[tet]: rapA(S17N)/ [act15]: gbpDgbpD | rapAincreased cell-substrate adhesion | increased cell polarity | aberrant cell morphology
DBS0304911[tre]: paxBpaxBabolished sporulation | aberrant endocytosis | decreased cell-substrate adhesion | aberrant chemotaxis to folate | development arrests at mound stage | decreased cell motility | increased cell-cell adhesion
DBS0304636[unk]: rasG(Q61L)/ rasG-rasGaberrant cAMP signaling during aggregation
DBS0237773[unk]: scrA(97-443): GFPscrAaberrant cytoskeleton organisation | increased cell size | aberrant cytokinesis | decreased chemotaxis to cAMP
DBS0237288[unk]skp1fpaA | fpaB-1aberrant fruiting body morphology
DBS0236102[unsuccessful][OE]gpaE(G196T)gpaEinviable
DBS0236104[unsuccessful][OE]gpaE(Q198L)gpaEinviable
DBS0309110[unsuccessful]mppA1-mppA1inviable
DBS0304463[unsuccessful]padA-padAinviable
DBS0237265[unsuccessful]phlp2-phlp2inviable
DBS0237266[unsuccessful]pho2A-pho2ainviable
DBS0237267[unsuccessful]phr2AB-phr2aBinviable
DBS0237268[unsuccessful]pikA-/ pikC-pikA | pikCinviable
DBS0237269[unsuccessful]pikB-/ pikC-pikB | pikCinviable
DBS0237503[unsuccessful]pikD-pikDinviable
DBS0266835[unsuccessful]ptpC-ptpCinviable
DBS0304462[unsuccessful]sir2E-sir2Einviable
DBS0304565[unsuccessful]sun1-sun1inviable
DBS0236980[unsuccessful]tcp1-tcp1inviable
DBS0237271[unsuccessful]top2mt-top2mtinviable
DBS0237272[unsuccessful]trrA-trrAinviable
DBS0306059[unsuccessful]vatM-vatMinviable
DBS0306103[unsuccessful]vatPvatPinviable
HAD186aarA-aarAaberrant tip formation | aberrant establishment and/ or maintenance of cell polarity | aberrant stalk formation | aberrant Golgi localization | aberrant centrosome localization | decreased sporulation | aberrant fruiting body morphology
DBS0236539abcG2-/ abcG18-abcG18 | abcG2decreased rate of endocytosis | abolished growth | decreased growth rate
DBS0236540abcG2-/ abcG18-/ rtoA-abcG18 | abcG2 | rtoAabolished growth | decreased growth rate
DBS0266687abiA-abiAdecreased protein level | aberrant cytokinesis | decreased growth rate | decreased chemotaxis to folate | aberrant protein localization
DBS0266688abiA-abiAaberrant protein localization
DBS0266689abiA-/ scrA-abiA | scrAdecreased cell motility | decreased cell size
DBS0235456abpA-/ abpC-abpA | abpCaberrant response to hyperosmotic stress | decreased phagocytosis | decreased growth rate | decreased cell motility | aberrant development
DBS0305672abpB-abpBincreased filopodium formation
DBS0235425abpB-/ fimA-abpB | fimAdecreased fruiting body size | decreased sporulation | decreased cell size
DBS0236077abpC-abpCaberrant thermotaxis | aberrant phototaxis
HG1270abpC-abpCaberrant phototaxis
DBS0237938abpC-/ [act15]: GFP: abpC(9-148)abpCaberrant phototaxis
DBS0235426abpC-/ [act15]: abpCabpCwild type
DBS0237945abpC-/ [act15]: abpC(1-348: 449-857): GFPabpCaberrant F-actin organization | aberrant phototaxis
DBS0237946abpC-/ [act15]: abpC(1-556: 644-857): GFPabpCaberrant F-actin organization | aberrant phototaxis
DBS0237941abpC-/ [act15]: abpC(1-739): GFPabpCaberrant phototaxis
DBS0237949abpC-/ [cotB]: abpC: GFPabpCaberrant phototaxis
DBS0237948abpC-/ [ecmA]: abpC: GFPabpCwild type
DBS0235427abpD-abpDdecreased cell-cell adhesion | decreased spore viability | delayed development | aberrant development
DBS0235428abpE-abpE-1 | abpE-2increased lateral pseudopod formation
DBS0349851abpE-abpE-1 | abpE-2increased phagocytosis
DBS0349852abpE-/ [act15]: abpEabpE-1 | abpE-2decreased phagocytosis
DBS0235562acaA-acaAabolished aggregation | decreased adenylate cyclase activity | abolished cell polarity | abolished streaming
GP6acaA-acaAaberrant F-actin organization | increased lateral pseudopod formation | decreased chemotaxis rate | aberrant cell morphology
DBS0306125acapA-acapAwild type
DBS0306126acapA-/ acapB-acapA | acapBdecreased sporulation
DBS0306127acapB-acapBwild type
TL177acbA-acbAincreased sensitivity to cisplatin | abolished SDF production | decreased spore viability | abolished sorting to prestalk region
AK1211acbA-/ tagA-acbA | tagAincreased prestalk B cell differentiation
DBS0235440acgA-acgAprecocious spore germination
DBS0237788acgA-acgAdecreased gene expression | decreased prespore cell differentiation
DBS0237790acgA-/ [acrA]: lacZacgA | acrAmislocalized gene expression
DG1100acrA-acrAdecreased gene expression | increased stalk length | spores inviable | decreased sporulation
DBS0237786acrA-/ [act15]: acgA(1-401)acgA | acrAdecreased gene expression | decreased prespore cell differentiation | decreased sporulation
DBS0238203adrm1-adrm1-1aberrant response to nutrients | precocious gene expression | precocious development
DBS0235457ahhA-ahhAaberrant culminant morphology
DBS0266759alp-alpwild type
DBS0235513alrA-alrAincreased aggregate size | decreased intracellular glucose level | decreased cell motility | decreased extracellular counting factor component(s) level
DBS0235473alrA-/ [act15]: alrAalrAwild type
DBS0235474alxA-alxAdevelopment arrests at loose aggregate stage | decreased growth rate | aberrant fruiting body morphology
DBS0235475alxA-alxAabolished sporulation | decreased gene expression | development arrests at mound stage | aberrant fruiting body morphology
DBS0235488alxA-/ [act15]: FLAG: alxAalxAdelayed development
DBS0235476alxA-/ [act15]: alxA(1-596): myc2alxAwild type
DBS0235477alxA-/ [act15]: alxA(1-697): myc2alxAwild type
DBS0235478alxA-/ [act15]: alxA(155-697): myc2alxAaberrant fruiting body morphology
DBS0235479alxA-/ [act15]: alxA(293-697): myc2alxAaberrant fruiting body morphology
DBS0235480alxA-/ [act15]: alxA(460-794): myc2alxAaberrant fruiting body morphology
DBS0235481alxA-/ [act15]: alxA(D310A/ N311A)alxAwild type
DBS0235482alxA-/ [act15]: alxA(Q181E/ Q183)alxAwild type
DBS0235483alxA-/ [act15]: alxA(S700A/ S704A/ S708A)alxAwild type
DBS0235484alxA-/ [act15]: alxA(S700D/ S704D/ S708D)alxAwild type
DBS0235485alxA-/ [act15]: alxA(Y315D)alxAwild type
DBS0235486alxA-/ [act15]: alxA(Y315F)alxAwild type
DBS0235487alxA-/ [act15]: alxA: myc2alxAwild type
DBS0235489alyA-alyAincreased phagocytosis
DG1114amdA-amdAdecreased spore viability | translucent sorus | increased prestalk A cell differentiation
HM1158amdA-amdAdecreased fruiting body size | decreased sporulation | increased aspidocyte differentiation
DBS0235490amiB-amiBabolished aggregation
DBS0235491amiB-amiBdecreased cAMP-induced cGMP pulse | abolished down-regulation of growth phase genes | decreased gene expression | abolished aggregation | decreased chemotaxis to cAMP | decreased cAMP-induced cAMP pulse
DBS0235493ampA-ampAdelayed tip formation | increased cell-cell adhesion | increased cell-substrate adhesion | mislocalized gene expression | delayed development | precocious gene expression | decreased prestalk cell differentiation | delayed gene expression
BS155amtA-amtAdecreased slug migration | decreased aggregate size | decreased fruiting body size | increased growth rate
DBS0267100amtA-amtAdecreased spore viability | decreased aggregate size | increased number of aggregates | decreased extracellular ammonia level | increased intracellular glucose level | decreased stalk length | increased intracellular ammonia level
DBS0267101amtA-/ [OE]: amtAamtAwild type
BS165amtA-/ amtC-amtA | amtCaberrant slug migration | decreased localization of protein to the nucleus | delayed gene expression
BS154amtC-amtCdecreased gene expression | development arrests at slug stage | mislocalized gene expression | delayed culmination | aberrant protein localization | aberrant fruiting body morphology
DBS0235501amtC-/ [act15]: cudAamtC | cudAdelayed culmination
DBS0235502amtC-/ [ecmA]: cudAamtC | cudAdelayed culmination
DBS0235503amtC-/ [pspA]: cudAamtC | cudAdevelopment arrests at slug stage
BS163amtC-/ dhkC-amtC | dhkCmislocalized gene expression
DBS0236890amtC-/ regA-amtC | regAprecocious sporulation
DBS0235505apm1-apm1aberrant contractile vacuole organization and biogenesis | decreased spore germination | aberrant response to hypo-osmotic stress | decreased growth rate | aberrant endosome morphology | delayed development | decreased stalk width
DBS0305085apm2-/ [dscB]: GFP: vamp7Aapm2 | vamp7Aincreased localization of protein to the plasma membrane
DBS0235507apm3-apm3decreased pinocytosis | increased exocytosis | aberrant post-lysosome organization and biogenesis | aberrant endosome morphology
DBS0305083apm3-/ [dscB]: GFP: vamp7Aapm3 | vamp7Aincreased localization of protein to the plasma membrane
DBS0235508apm4-apm4wild type
DBS0235509aprA-aprAincreased aggregate size | decreased spore viability | aberrant cytokinesis | increased growth rate | aberrant fruiting body morphology | decreased sporulation
DBS0235510aprA-/ actin15: : aprAaprAdecreased growth rate | aberrant fruiting body morphology
DBS0238124aqpA-aqpAdecreased spore viability
HM2245arcB(I191L/ D197Y/ K206V/ A213V/ F223L/ P224S/ E232G/ I237T/ H245L/ S250S)arcBdecreased F-actin polymerization | decreased growth rate | decreased cell motility | decreased pseudopod formation | decreased chemotaxis rate
DBS0235511arkA-arkAincreased gene expression | aberrant fruiting body morphology
DBS0235512arkA-/ [arkA]: arkA: myc2arkAaberrant aggregation
DJK45arpB+/ arpB-arpBwild type
DMZ10arpB+/ arpB-/ [act15]: myc: arpBarpBwild type
MZ10arpB-/ [act15]: myc: arpBarpBwild type
DBS0235514aslA-aslA-1 | aslA-2wild type
DBS0236305atg1-atg1aberrant macroautophagy | abolished autophagic vacuole formation
DBS0236304atg1-atg1aberrant macroautophagy | abolished autophagic vacuole formation
HR131atg1-atg1abolished sporulation | decreased growth rate in suspension | abolished macroautophagy | increased number of autophagosomes | aberrant cellular response to nitrogen starvation | abolished stalk cell differentiation | abolished aggregation | decreased growth rate on bacterial plates
DBS0238085atg1-/ [act15]: atg1atg1wild type
DBS0238092atg1-/ [act15]: atg1(1-628)atg1aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238087atg1-/ [act15]: atg1(K36A)atg1aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238089atg1-/ [act15]: atg1(K36A/ 1-628)atg1aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238093atg1-/ [act15]: atg1(P138S)atg1abolished aggregation
DBS0266655atg1-/ iplA-atg1 | iplAdecreased necrotic cell death
DBS0252632atg1-/ pcp-atg1 | pcpabolished autophagic vacuole formation
HR75atg5-atg5aberrant macroautophagy | abolished sporulation | aberrant cellular response to nitrogen starvation | multiple tips | abolished aggregation
HR174 atg6-atg6Aaberrant macroautophagy | aberrant cellular response to nitrogen starvation | multiple tips | decreased fruiting body size | decreased stalk length | decreased sporulation
HR79atg7-atg7aberrant macroautophagy | abolished sporulation | aberrant cellular response to nitrogen starvation | multiple tips
HR141atg8-atg8aberrant macroautophagy | aberrant spore morphology | increased sensitivity to cisplatin | aberrant cellular response to nitrogen starvation | multiple tips | decreased fruiting body size | decreased sporulation
DBS0305977atg9-atg9increased stalk width | aberrant sorus morphology | decreased phagocytosis | decreased growth rate | aberrant slug migration | aberrant fruiting body morphology | aberrant slug formation | multiple tips in mound
DBS0305978atg9-/ [act15]: GFP: atg9atg9wild type
DBS0305979atg9-/ [act15]: atg9: GFPatg9wild type
TL97cadA-cadAmultiple tips | decreased sporulation | delayed culmination | increased prestalk cell differentiation
DBS0235563capB-truncatedcapBdecreased growth rate | delayed development
DBS0235568car4-carDincreased gene expression | decreased gene expression | aberrant fruiting body morphology
RI4carA-/ carC-carA-1 | carA-2 | carCdecreased chemoattractant-mediated F-actin polymerization | decreased cAMP-induced cGMP pulse | abolished aggregation
DBS0235570carB-carBdevelopment arrests at mound stage
DBS0235573carmil-carmildecreased pinocytosis | decreased growth rate | decreased basal F-actin level | decreased aggregate size
DBS0266775catA-catAabolished catalase activity
X9catA-catAincreased sensitivity to H2O2 (peroxide) | abolished catalase activity
IR40catA-catAabolished catalase activity
IR41catA-catAabolished catalase activity
IR29catA-catAincreased sensitivity to H2O2 (peroxide)
DBS0235574catB-catBspores hypersensitive to H2O2 (peroxide) | delayed development
DBS0304455cblA-cblA-1 | cblA-2abolished basal disc formation | aberrant slug formation | aberrant signal transduction
DBS0235575cbpJ-cbpJwild type
DBS0235661cdk8-cdk8decreased gene expression | mislocalized gene expression | abolished aggregation
DBS0235578cdk8-/ [cdk8]: cdk8cdk8wild type
DBS0306226cenB-cenBabolished localization of protein to the microtubule organizing center | increased number of centrosomes | aberrant cell separation during cytokinesis | aberrant nuclear envelope morphology | aberrant nucleus morphology | aberrant cytokinesis | decreased microtubule nucleation | aberrant centrosome organization
DBS0306227cenB-/ [act15]: RFP: cenBcenBwild type
DBS0302444cfaD-cfaDincreased growth rate | aberrant fruiting body morphology
DBS0302446cfaD-/ [act15]: cfaDcfaDwild type
HO101chcA-chcAdecreased pinocytosis | aberrant cytokinesis | decreased growth rate
HO103chcA-chcAabolished sporulation | abolished cytokinesis | abolished gene expression | delayed aggregation | abolished growth in suspension | aberrant fruiting body morphology
DBS0235588chcA-/ [act15]: GFP: mhcAchcA | mhcAdecreased positive regulation of GTPase activity
DBS0302455chcA-/ [act15]: epnA: GFPchcA | epnAaberrant localization of a protein to coated pits
DBS0235589chcA-/ [cotB]: lacZchcAmislocalized gene expression
DBS0235590chcA-/ [ecmA]: lacZchcAmislocalized gene expression
DBS0235591chcA-/ [ecmB]: lacZchcAmislocalized gene expression
DBS0235592chcA-/ [pspA]: lacZchcAmislocalized gene expression
DBS0235601clc-clcabolished cytokinesis | aberrant response to hypo-osmotic stress | abolished growth | aberrant fruiting body morphology
DBS0235604clc-/ [act15]: GFP-clc(146-194)clcabolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0235605clc-/ [act15]: GFP-clc(85-124)clcabolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0235607clc-/ [act15]GFP: clc(1-124)clcabolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0235608clmA-clmAaberrant response to hypo-osmotic stress
DBS0235613cnrB-cnrBwild type
DBS0302655cnrN-cnrNaberrant streaming | increased cAMP-induced cAMP pulse | increased F-actin polymerization | increased number of aggregates
HG1770cnxA-cnxAdecreased extracellular Ca2+ uptake | increased cytosolic Ca2+ response
DBS0235615cofB-cofBwild type
DBS0235616cofC-cofC-1wild type
DBS0235617comB-comBabolished culmination
DG1016comB-comBabolished culmination
DBS0235618comC-comCaberrant streaming | aberrant aggregation
DBS0235619comD-comDabolished culmination
DBS0235620comE-comEtranslucent sorus | aberrant fruiting body morphology
DBS0235621comF-comF-1 | comF-2abolished aggregation
DBS0235622comG-comGdevelopment arrests at mound stage | multiple tips
DBS0235623comH-comHdevelopment arrests at mound stage
HG1570corA-corAaberrant cytokinesis | decreased growth rate | decreased cell motility | aberrant cell morphology
HG1571corA-corAaberrant cytokinesis | decreased growth rate | decreased cell motility | aberrant cell morphology
HG1569corA-corAaberrant cytokinesis | decreased growth rate | decreased cell motility | aberrant cell morphology
DBS0305825corB-corBaberrant phagocytosis | decreased growth rate | increased lateral pseudopod formation | increased cell-substrate adhesion
TL55cotA-cotAaberrant spore coat morphology
TL53cotA-/ cotB-cotA | cotBaberrant spore coat morphology
TL56cotA-/ cotB-/ cotC-cotA | cotB | cotCaberrant spore coat morphology
TL57cotA-/ cotB-/ cotC-cotA | cotB | cotCaberrant spore coat morphology
TL54cotB-/ cotC-cotB | cotCaberrant spore coat morphology
TL52cotC-cotCaberrant spore coat morphology
HW07cotE(1-235)cotEaberrant spore coat morphology
DBS0238297cpnA-cpnAdelayed response to hypo-osmotic stress | decreased culmination | decreased growth rate | aberrant cytokinesis | delayed development | aberrant fruiting body morphology
DBS0238320cpnA-/ [act15]: GFP: cpnAcpnAdelayed response to hypo-osmotic stress | decreased culmination | delayed development
DBS0235627crlA-crlAincreased aggregate size | delayed tip formation | decreased sorting to prestalk region | increased growth rate
DBS0235628crlA-/ [crlA]: crlAcrlAincreased aggregate size
DBS0235629crlB-crlBwild type
DBS0235630crlC-crlCwild type
HG1768crtA-crtAdecreased extracellular Ca2+ uptake | increased cytosolic Ca2+ response
HG1772crtA-/ cnxA-cnxA | crtAdecreased growth rate in suspension | delayed response to cAMP | decreased extracellular Ca2+ uptake | decreased phagocytosis | increased cytosolic Ca2+ response | decreased growth rate on bacterial plates
DBS0235633crtf-crtfabolished sporulation | decreased gene expression | abolished aggregation
TL73csaA-/ csbA-/ csbC-/ csbC-csaA | csbA | csbB | csbCaberrant culminant morphology
TL72csbA-/ csbB-/ csbC-csbA | csbB | csbCincreased resistance to cisplatin | aberrant culminant morphology
WTC127cshA-cshAdevelopment arrests at loose aggregate stage | decreased phagocytosis | decreased growth rate | delayed aggregation
DBS0235634csn5-KDcsn5decreased growth rate
DBS0235624ctnA-ctnAdecreased protein level | increased cAMP-induced cGMP pulse | increased aggregate size | decreased basal F-actin level | increased cell-cell adhesion | increased GTP-gamma-S-stimulated guanylyl cyclase activity | increased protein level | increased cell motility | increased intracellular glucose level | decreased cAMP-induced cAMP pulse | decreased myosin II assembly
DBS0235636ctnB-ctnBdecreased gene expression | increased number of aggregates | decreased fruiting body size
DBS0304927ctnnA-ctnnAwild type
DBS0304928ctnnA-/ mhcA-ctnnA | mhcAaberrant cytokinesis
DG1071ctr9-ctr9aberrant fruiting body morphology
DG1058ctrA-ctrAdecreased fruiting body size
DBS0235598ctxA-ctxAaberrant cytokinesis | aberrant cell morphology
HS1151ctxA-ctxAaberrant cytokinesis | decreased growth rate
DBS0237568ctxA-/ [RNAi]enlActxA | enlAwild type
DBS0237536ctxA-/ [act15]: enlA(92-497)ctxA | enlAwild type
DBS0235599ctxA-/ ctxB-ctxA | ctxBaberrant regulation of Rap GTPase activity | aberrant cytokinesis | aberrant cell morphology
DBS0235600ctxB-ctxBaberrant cytokinesis | aberrant cell morphology
DBS0235639cudA-cudAabolished sporulation | decreased gene expression | development arrests at slug stage | abolished stalk cell differentiation
DBS0235640culA-culAmultiple tips | development arrests at tipped mound stage
DBS0235641culA-/ [cotC]: culAculAincreased sorus size | decreased stalk length | decreased sporulation
DBS0235642culA-/ [ecmA]: culAculAincreased sorus size | decreased stalk length
DBS0235643culA-/ [pkaC]pkaCculA | pkaCwild type
DBS0266745culB-culBdecreased fruiting body size | precocious gene expression | aberrant slug formation | decreased sporulation | multiple tips in mound
DBS0266761culB-/ [act15]: pkaCculB | pkaCabolished gene expression | abolished sporulation | precocious gene expression | abolished aggregation
DBS0266760culB-/ pkaR-culB | pkaRabolished gene expression | abolished sporulation | precocious gene expression | abolished aggregation
DBS0235651cybA-cybAabolished sporulation | aberrant development
AK108dagA-dagAabolished gene expression | decreased gene expression | abolished activation of adenylate cyclase | abolished aggregation
DBS0235652dagA-/ [act15]: dagAdagAwild type
DBS0235653darA-darAdecreased cell polarity | decreased cell motility | decreased aggregate size | abolished aggregation
DBS0236307dcsA-dcsAabolished cellulose biosynthesis
DG1099dcsA-dcsAabolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | abolished stalk formation | abolished stalk cell differentiation
DG1128dcsA-dcsAabolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | abolished stalk formation
TL127dcsA-dcsAabolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | aberrant stalk formation | abolished stalk formation | abolished stalk cell differentiation
TL128dcsA-/ [act15]: dcsAdcsAwild type
DBS0349804detA-detAincreased aggregate size | decreased growth rate | delayed development
DBS0349807detA-/ [act6]: GFP: detAdetAwild type
DBS0349816detA-/ [act6]: GFP: detA/ [act6]: 3xHA: culDculD | detAincreased gene expression
DBS0349817detA-/ [act6]: GFP: detA/ [act6]: 3xHA: repEdetA | repEincreased gene expression
DBS0349813detA-/ [cotB]: GFPdetAdecreased prespore cell differentiation
DBS0349811detA-/ [ecm0]: lacZdetAaberrant prestalk O cell differentiation
DBS0349812detA-/ [ecmA0]: GFPdetAincreased prestalk cell differentiation
DBS0349808detA-/ [ecmA0]: lacZdetAincreased prestalk cell differentiation
DBS0349809detA-/ [ecmA]: lacZdetAincreased prestalk A cell differentiation
DBS0349810detA-/ [ecmB]: lacZdetAdelayed development
DBS0235695dgkA-dgkAdecreased spore viability | increased myosin II assembly | decreased chemotaxis rate | aberrant development
AK299dhkA-dhkAaberrant stalk morphogenesis | increased sporulation in the presence of 8-Br-cAMP | increased gene expression | mislocalized gene expression | decreased sporulation | aberrant fruiting body morphology
TL134dhkA-/ dhkB-dhkA | dhkBabolished sporulation | increased stalk length | decreased stalk width
HR49dhkA-/ fbxA-dhkA | fbxAdecreased intracellular cAMP level | aberrant fruiting body morphology | decreased sporulation
HR51dhkA-/ fbxA-dhkA | fbxAaberrant fruiting body morphology | decreased sporulation
HR50dhkA-/ fbxA-dhkA | fbxAabolished culmination | decreased sporulation
DBS0235704dhkB-dhkBprecocious spore germination
TL135dhkC-dhkCprecocious culmination | decreased spore germination | precocious aggregation | precocious development
DBS0235710dhkK-dhkKaberrant slug migration | delayed culmination | delayed gene expression
DBS0235712dhkK-/ [act15]: dhkK(D1125N)dhkKaberrant fruiting body morphology
DBS0235714dhkK-/ regA-dhkK | regAprecocious development
DBS0348046dhkM-dhkMabolished autophagic vacuole formation | delayed development
DBS0348047dhkM-dhkMabolished autophagic vacuole formation | delayed development
DBS0235719dia1-/ [act6]: trap1dia1 | trap1aberrant aggregation | decreased fruiting body size
DBS0235895dimA-dimAthin fingers | long fingers | abolished prestalk cell differentiation | increased slug size | increased prespore cell differentiation | decreased prestalk O cell differentiation | aberrant fruiting body morphology
DBS0235899dimA-/ dimB-dimA | dimBthin fingers | long fingers | increased slug size
DBS0235901dimB-dimBabolished response to DIF
DBS0235903dimB-/ [act15]: dimA: GFPdimA | dimBabolished localization of protein to the nucleus
DBS0235904dimB-/ [act15]: dimB: GFPdimBwild type
DBS0235902dimB-/ [cotB]: lacZdimBincreased prespore cell differentiation
DBS0235906dimB-/ [ecmAO]: lacZdimBdecreased prestalk O cell differentiation
DBS0235907dimB-/ [ecmO]: lacZdimBaberrant prestalk cell differentiation
DBS0302609disgorgin(1-571: 581-733)DDB_G0280955aberrant contractile vacuole organization and biogenesis
DBS0302608disgorgin(1-571: 581-733)/ disgorgin-DDB_G0280955aberrant contractile vacuole organization and biogenesis | aberrant cellular localization
DBS0302597disgorgin-DDB_G0280955aberrant contractile vacuole organization and biogenesis | aberrant response to hypo-osmotic stress
DBS0302607disgorgin-/ [OE]: lvsADDB_G0280955 | lvsAaberrant contractile vacuole organization and biogenesis
DBS0302606disgorgin-/ [OE]: lvsDDDB_G0280955 | lvsDwild type
DBS0302678disgorgin-/ [OE]: rab8ADDB_G0280955 | rab8Aaberrant contractile vacuole organization and biogenesis
DBS0302604disgorgin-/ lvsA-DDB_G0280955 | lvsAwild type
DBS0302605disgorgin-/ lvsD-DDB_G0280955 | lvsDaberrant contractile vacuole organization and biogenesis
DBS0304919dlpA-dlpAaberrant cytokinesis
DBS0304920dlpB-dlpBaberrant cytokinesis
DBS0304921dlpC-dlpCaberrant cytokinesis
DBS0235913dmpA-dmpAaberrant streaming | translucent sorus | delayed development | decreased stalk cell differentiation | decreased sporulation | aberrant fruiting body morphology
HM1030dmtA-dmtAthin fingers | decreased outer basal disc size | abolished prestalk O cell differentation | abolished DIF production | delayed tip formation | decreased lower cup size | delayed development | decreased prestalk O cell differentiation | aberrant fruiting body morphology | decreased prestalk cell differentiation
HM1196dmtA-/ stlA-dmtA | stlBdecreased outer basal disc size | decreased prestalk O cell differentiation
DBS0235914dnapkcs-dnapkcsincreased sensitivity to DNA-damaging agents
DBS0266875dnapkcs-/ GFP: pcnadnapkcs | pcnaaberrant response to DNA damaging agents
DBS0235915dng1-dng1decreased growth rate | delayed aggregation
DBS0235917dnmA-dnmAdecreased cytosine methylation in genomic DNA
DBS0235916dnmA-dnmAaberrant culminant morphology | translucent sorus | decreased cytosine methylation in genomic DNA | decreased sporulation
DG2015docA-docAdevelopment arrests at mound stage
DBS0235920dokA-dokAaberrant response to hyperosmotic stress | translucent sorus | decreased sporulation
DBS0349789dotA-dotAdecreased growth rate | increased sensitivity to UV light | decreased spore size | delayed development | abolished histone H3-K79 methylation
HAD172dpoA-dpoAaberrant development
HAD200dpoA-dpoAaberrant development
HAD201dpoA-dpoAaberrant development
HAD202dpoA-dpoAaberrant development
HAD203dpoA-dpoAaberrant development
HAD205dpoA-/ gskA-dpoA | gskAaberrant development
DBS0238474drkC-drkCdecreased phagocytosis | decreased phagolysosome formation
DBS0238511drkC-/ [act15]: drkC(1-497): YFPdrkCdecreased phagocytosis
DBS0238513drkC-/ [act15]: drkC(K518R): YFPdrkCdecreased phagocytosis
DBS0238475drkC-/ [act15]: drkC: YFPdrkCwild type
DBS0235922drnA-drnA-1decreased gene expression
DBS0235924dscA-dscA-1 | dscA-2aberrant cell morphology
DBS0235925dstA-dstAabolished gene expression | increased gene expression | decreased gene expression | delayed aggregation | mislocalized gene expression | decreased cell motility | abolished stalk cell differentiation | abolished sorting to prestalk region | aberrant fruiting body morphology
DBS0235926dstA-dstAdelayed aggregation | mislocalized gene expression | decreased cell motility | abolished stalk cell differentiation | abolished sorting to prestalk region | aberrant fruiting body morphology
DBS0238237dstA-/ GFP: dstA(237-707): ORF+dstAabolished culmination | decreased stalk length
DBS0238236dstA-/ GFP: dstA(237-707): ORF+/ [OE]dutA(751-1322)dstA | dutAdecreased stalk length
DBS0252824dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 2C2C | dstAaberrant fruiting body morphology
DBS0252823dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 7E7E | dstA | hssBwild type
DBS0252826dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0276165DDB_G0276165 | dstAaberrant fruiting body morphology
DBS0252825dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0282325DDB_G0282325 | dstAaberrant fruiting body morphology
DBS0252816dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssAdstA | hssAwild type
DBS0252822dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssBdstA | hssBwild type
DBS0235928dstA-/ [act15]: dstAdstAwild type
DBS0235929dstA-/ [cprB]: dstAdstAwild type
DBS0235930dstA-/ [ecmAO]: dstAdstAwild type
DBS0235927dstA-/ dstB-dstA | dstBwild type
DBS0235931dstB-dstBdecreased gene expression | increased gene expression | decreased growth rate
DBS0235933dstB-/ [act15]: dstBdstBwild type
DBS0235934dstB-/ [act15]: dstB(L1025R)dstBwild type
DBS0235935dstB-/ [act15]: dstB(Y1143F)dstBwild type
DBS0235932dstB-/ dstC-dstB | dstCwild type
DBS0235937dtfA-dtfAdelayed tip formation | aberrant cytokinesis | aberrant fruiting body morphology
DBS0238234dutA-dutAwild type
DBS0235939dwwA-dwwAaberrant cytokinesis | aberrant F-actin organization | aberrant cell morphology
DBS0347874dymA-dymAdecreased pinocytosis | aberrant cell separation during cytokinesis | decreased cell polarity | aberrant mitochondrion morphology | increased cell size | increased basal disc size | decreased growth rate | aberrant stalk formation | aberrant nucleus morphology | aberrant endosome morphology | delayed development | aberrant pseudopod formation | increased phagocytosis | aberrant fruiting body morphology
DBS0349839dymA-/ [dymA]: dymAdymAwild type
HJW117ecmA-ecmAthin fingers | weak slime trail | long fingers
HJW01ecmB-ecmBwild type
HJW03ecmB-ecmBwild type
DBS0235944ecmF-ecmFwild type
DBS0235946egeB-egeBdevelopment arrests at mound stage
DBS0302590elmoA-elmoAdecreased culmination | increased pseudopod formation | increased localization of protein to the pseudopodium | increased F-actin polymerization | decreased cell motility | delayed development | abolished cell polarity | increased phagocytosis
DBS0302598elmoA-/ [act15]: elmoA(1-903/ 959-977): GFPelmoAdecreased cell motility | increased phagocytosis
DBS0302591elmoA-/ [act15]: elmoA: GFPelmoAwild type
DBS0302448epnA-epnAaberrant spore morphology | decreased spore viability | aberrant cytokinesis | abolished protein phosphorylation | aberrant protein localization
DBS0302457epnA-/ [act15]: GFP: epnA(253-677)epnAabolished localization of protein to the plasma membrane | aberrant spore morphology | abolished localization of protein to coated pits
DBS0302456epnA-/ [act15]: epnA(1-133): GFPepnAaberrant localization of a protein to coated pits
DBS0302474epnA-/ [act15]: epnA(R65A/ K78A): GFPepnAabolished localization of protein to the plasma membrane | aberrant spore morphology | abolished phosphatidylinositol-4,5-bisphosphate binding | abolished localization of protein to coated pits
DBS0302475epnA-/ [act15]: epnA(T107A): GFPepnAaberrant spore morphology
DBS0302454epnA-/ [act15]: epnA: GFPepnAwild type
DBS0235947eppA-eppAdecreased growth rate | delayed development | decreased chemotaxis to folate | decreased chemotaxis to cAMP | decreased intracellular cAMP level
DBS0235948eppA-/ [act6]: myc: eppAeppAwild type
HS174erkB-erkBdecreased cell motility | abolished aggregation | decreased chemotaxis to cAMP | decreased cAMP-induced cAMP pulse | decreased sporulation
AK240erkB-erkBabolished aggregation | decreased cAMP-induced cAMP pulse | decreased sporulation
DBS0235949erkB-/ regA-erkB | regAincreased cAMP-induced cAMP pulse | abolished aggregation
DBS0304864expl7-expl7wild type
DBS0235951fadA-fadAincreased resistance to heat shock
DBS0235952fadB-fadBwild type
DBS0236034fam45-fam45wild type
DBS0236040fam91-fam91wild type
DBS0235953fbxA-fbxAdecreased sporulation
DBS0235954fbxA-/ [ecmA]: GFP(S65T)fbxAincreased prespore cell differentiation
HR46fbxA-/ regA-fbxA | regAaberrant fruiting body morphology | decreased sporulation
HR48fbxA-/ regA-fbxA | regAaberrant fruiting body morphology | decreased sporulation
DBS0235956fbxA1-fbxAdevelopment arrests at slug stage | increased slug migration | aberrant fruiting body morphology | delayed culmination
DBS0235957fbxA2-fbxAdevelopment arrests at slug stage | increased slug migration | aberrant fruiting body morphology | delayed culmination
DBS0235958fbxA3-fbxAdevelopment arrests at slug stage | increased slug migration | aberrant fruiting body morphology | delayed culmination
DG1148fcpA-fcpAaberrant fruiting body morphology
DBS0235960fcsA-fcsAdecreased fatty acid level
DBS0235961fimA-fimAdecreased cell size
HM1253fncD2-fncD2increased sensitivity to cisplatin
HM1351 fncD2-/ rev3-fncD2 | rev3increased sensitivity to cisplatin
HM1405fncD2-/ xpf-fncD2 | xpfincreased sensitivity to cisplatin
HM1416fncE-fncEincreased sensitivity to cisplatin
HM1356fncI-fncIincreased sensitivity to cisplatin
HM1302fncL-fncLincreased sensitivity to cisplatin
HM1407fncM-fncMincreased sensitivity to cisplatin
DBS0235966forA-forAwild type
DBS0235967forA-/ forB-forA | forBwild type
DBS0235968forB-forBwild type
DBS0235969forC-forCaberrant culmination | development arrests at tipped mound stage | aberrant fruiting body morphology
DBS0304905forC-/ [act15]: GFP-forCforCwild type
DBS0235970forH-forHdecreased cell-substrate adhesion | decreased chemotaxis rate | increased cell motility | aberrant pseudopod formation | aberrant cell morphology | decreased filopodium formation
DBS0235971forH-/ [act15]: GFP: forHforHincreased filopodium formation | decreased cell motility | increased cell-substrate adhesion
DBS0302506frmA-frmAdelayed aggregation | decreased cell motility | increased cell-substrate adhesion | decreased aggregate size | aberrant cell morphology
DBS0304440frmA-/ [unk]: GFPfrmAdecreased gene expression | increased cell-cell adhesion | delayed development | aberrant development | abolished phototaxis
DBS0302507frmA-/ [unk]: frmA-HAfrmAwild type
DBS0235976fszA- fszAdecreased number of mitochondria | increased number of tubular mitochondria
DBS0235978fszA-/ fszB- fszA | fszBincreased number of tubular mitochondria
DBS0235980fszB- fszBdecreased number of mitochondria | increased number of tubular mitochondria | decreased growth rate
DG1066fut1-fut1aberrant fruiting body morphology
DBS0305025gabT-gabTprecocious development | decreased sporulation
DBS0305026gabT-[pkaC]: pkaCgabT | pkaCaberrant protein secretion
DG1094gacT-gacTaberrant fruiting body morphology
DBS0235989gadA-gadAabolished SDF production | decreased sporulation
TL198gbfA-gbfAabolished gene expression | development arrests at mound stage
DBS0305094gbfA-gbfAabolished autophagic cell death | abolished autophagic vacuole formation
DBS0235992gbpA-/ gbpB-pdeD | pdeEincreased myosin light chain kinase activation
DBS0235993gbpB-pdeEaberrant chemotaxis to cAMP
DBS0235994gbpC-gbpCdecreased myosin light chain kinase activation | decreased fruiting body size
DBS0235995gbpC-gbpCdecreased cell polarity | aberrant myosin II organization | decreased chemotaxis rate | aberrant cell morphology | decreased fruiting body size
DBS0302680gbpC-gbpCdecreased aggregate size | abolished aggregation
DBS0304912gbpC-/ [act15]: gbpCgbpCwild type
DBS0304917gbpC-/ [act15]: gbpC(1-1698: 2005-2631)gbpCdecreased chemotaxis to cAMP
DBS0304918gbpC-/ [act15]: gbpC(311-2631)gbpCdecreased chemotaxis to cAMP
DBS0304916gbpC-/ [act15]: gbpC(F1892A)gbpCdecreased chemotaxis to cAMP
DBS0304915gbpC-/ [act15]: gbpC(F2082A/ E2084A/ F2564A/ E2566A)gbpCdecreased chemotaxis to cAMP
DBS0304913gbpC-/ [act15]: gbpC(K342N)gbpCdecreased chemotaxis to cAMP
DBS0304914gbpC-/ [act15]: gbpC(K905W)gbpCdecreased chemotaxis to cAMP
DBS0235996gbpC-/ gbpD-gbpC | gbpDdecreased cell polarity | decreased chemotaxis rate
DBS0235997gbpD-gbpDdecreased lateral pseudopod formation | decreased cell-substrate adhesion | increased cell polarity | increased chemotaxis rate
DBS0235998gbpD-/ [act15]: gbpDgbpDaberrant F-actin organization | increased cell-substrate adhesion | increased lateral pseudopod formation | decreased chemotaxis rate | abolished aggregation
DG1120gbqA-gbqAaberrant fruiting body morphology
DBS0236000gca-/ sgcA-gcA | sgcAdecreased myosin light chain kinase activation
DBS0302679gca-/ sgcA-gcA | sgcAaberrant streaming | aberrant chemotaxis to cAMP | increased lateral pseudopod formation | decreased chemotaxis rate | decreased aggregate size | decreased fruiting body size
DBS0236002gcsA-gcsAabolished gene expression | development arrests at mound stage | inviable | cell cycle arrest | spores inviable
DBS0236003gcsA-/ [act15]: gcsAgcsAdecreased spore viability | development arrests at mound stage
DBS0236004gdt1-gdt1decreased growth rate in suspension | increased gene expression | precocious aggregation
DBS0237190gdt1-/ [act15]: pkaR(G135E/ G261A)gdt1 | pkaRincreased gene expression | abolished aggregation
DBS0236095gdt1-/ gpaB-gdt1 | gpaBincreased gene expression | abolished aggregation
DBS0236006gdt2-gdt2increased gene expression | precocious aggregation
DBS0252697gefA-gefAdecreased cell motility
RI19gefA-gefAdecreased chemoattractant-mediated F-actin polymerization | decreased cAMP-induced cGMP pulse | decreased chemotaxis rate | abolished activation of adenylate cyclase | abolished aggregation | decreased cAMP-induced cAMP pulse
JB10gefA-gefAabolished aggregation
DBS0236009gefB-gefBaberrant cytoskeleton organisation | abolished pinocytosis | increased basal F-actin level | abolished growth | delayed aggregation | decreased phagocytosis | decreased growth rate | decreased aggregate size | aberrant cell morphology | aberrant fruiting body morphology
DBS0236010gefB-/ rasS-gefB | rasSdecreased phagocytosis | increased cell motility
DBS0236868gefC-gefCwild type
DBS0236869 (DBS0235543)gefD-gefDwild type
DBS0236870gefE-gefEaberrant thermotaxis | aberrant phototaxis
DBS0236011gefG-gefGwild type
DBS0236012gefK-gefKwild type
DBS0236871gefL-gefLaberrant thermotaxis | aberrant phototaxis
HSB61gefM-gefMincreased cAMP-induced cGMP pulse | aberrant activation of adenylate cyclase activity | development arrests at mound stage | decreased chemotaxis rate | decreased lateral pseudopod suppression | decreased cAMP-induced cAMP pulse
DBS0304968gefQ-gefQabolished Ras guanyl-nucleotide exchange factor activity | increased myosin II assembly | increased lateral pseudopod formation | abolished sorting to prestalk region | decreased fruiting body size | abolished phototaxis | multiple tips in mound
DBS0304985gefQ-/ [act15]: GFP: gefQ(172-654)gefQabolished Ras guanyl-nucleotide exchange factor activity | decreased phototaxis
DBS0304986gefQ-/ [act15]: GFP: gefQ(910-1298)gefQdecreased phototaxis
DBS0236014gefR-gefRwild type
DG1109ggtA-ggtAaberrant fruiting body morphology
DBS0266723glcS-/ DH1glcSaberrant stalk morphogenesis | decreased spore size | decreased intracellular glycogen level | decreased fruiting body size
DBS0266765glcS-/ HMXglcSabolished cellulose biosynthesis | decreased autophagic vacuole formation | aberrant cell morphology
DBS0236078glpD-glpDaberrant glycogen metabolism
DBS0236079gmsA-gmsAdecreased sexual fusion
DBS0236080gmsA-gmsAdecreased sexual fusion
DBS0238384gnt14-gnt14wild type
DBS0238382gnt15-gnt15decreased gene expression | decreased growth rate | increased calcium-independent cell-cell adhesion | abolished aggregation | abolished culmination
DBS0238383gnt15-gnt15decreased gene expression | decreased growth rate | increased calcium-independent cell-cell adhesion | abolished aggregation | abolished culmination
DBS0238390gnt15-/ [act15]: FLAG: gnt15gnt15wild type
DBS0238391gnt15-/ [act15]: FLAG: gnt15gnt15wild type
DBS0236082gol-golincreased resistance to cisplatin
DBS0236087gpaA-gpaAincreased stalk length | decreased stalk width
JH131gpaA-gpaAwild type
DBS0236091gpaA-/ [ecmB]: lacZgpaAdecreased gene expression
DBS0236092gpaA-/ [gpaA]: gpaA(G45V)gpaAdelayed development
DBS0236093gpaA-/ [gpaA]: gpaA(Q206L)gpaAincreased basal disc size
DBS0238605gpaA-/ rpkA-gpaA | rpkAdelayed aggregation | abolished aggregation
DBS0236575gpaB-gpaBdecreased cAMP-induced cGMP pulse | decreased cAMP-induced cAMP pulse
JH104gpaB-gpaBdecreased gene expression | abolished activation of adenylate cyclase | abolished aggregation
DBS0236096gpaB-/ [act15]: gpaBgpaBabolished aggregation
DBS0266942gpaB-/ [act15]: gpaBgpaBdelayed aggregation
DBS0266939gpaB-/ [act15]: gpaB(1-345): gpaD(337-345)gpaB | gpaDabolished aggregation
DBS0237137gpaB-/ [act15]: gpaB(D154V)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237138gpaB-/ [act15]: gpaB(E190G)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased cAMP-induced cAMP pulse
DBS0237139gpaB-/ [act15]: gpaB(I104S)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237140gpaB-/ [act15]: gpaB(L110S)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237141gpaB-/ [act15]: gpaB(L76P)gpaBabolished aggregation
DBS0237142gpaB-/ [act15]: gpaB(N74D)gpaBdecreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | abolished aggregation | decreased cAMP-induced cAMP pulse
DBS0237143gpaB-/ [act15]: gpaB(R64G)gpaBdecreased chemotaxis rate | abolished aggregation
DBS0237144gpaB-/ [act15]: gpaB(S155P)gpaBdecreased chemotaxis rate | abolished aggregation
DBS0236097gpaB-/ [gpaA]: gpaBgpaBabolished aggregation
DBS0236099gpaB-/ [gpaB]: gpaBgpaBwild type
DBS0236098gpaB-/ [gpaB]: gpaB(Q208L)gpaBaberrant protein localization
DBS0235986gpaC-gpaCincreased protein kinase A activity | aberrant activation of adenylate cyclase activity | decreased gene expression | abolished aggregation
JH417gpaD-gpaDdecreased gene expression | abolished SDF production | decreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology | decreased sporulation
DBS0266944gpaD-/ [act15]: gpaBgpaB | gpaDdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266946gpaD-/ [act15]: gpaB(1-345): gpaD(337-345)gpaB | gpaDdecreased accumulation of cGMP | aberrant fruiting body morphology
DBS0266943gpaD-/ [act15]: gpaDgpaDwild type
DBS0266945gpaD-/ [act15]: gpaEgpaD | gpaEdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266947gpaD-/ [act15]: gpaE(1-339): gpaD(337-345)gpaD | gpaEdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0236101gpaE(G196T)gpaEwild type
DBS0236103gpaE(Q198L)gpaEwild type
JH257gpaE-gpaEdelayed tip formation | delayed gene expression
DBS0266941gpaE-/ [act15]: gpaEgpaEprecocious tip formation
DBS0266948gpaE-/ [act15]: gpaE(1-339): gpaD(337-345)gpaD | gpaEprecocious tip formation
LW1gpaG-gpaGwild type | aberrant gamma-aminobutyric acid signaling pathway | abolished SDF production
DBS0236107gpaH-gpaHwild type
DBS0236108gpaH-gpaHwild type
DBS0236109gpaI-gpaIprecocious aggregation | decreased aggregate size | increased number of aggregates | decreased fruiting body size
LW5gpbA-gpbAabolished aggregation
LW6gpbA-gpbAdecreased CRAC localization to the plasma membrane | decreased positive regulation of Ras GTPase activity | decreased cAMP-induced cGMP pulse | decreased chemotaxis to folate | decreased chemotaxis to cAMP | decreased cAMP-induced cAMP pulse | aberrant protein localization
DBS0304814grlA-grlAdecreased gene expression | abolished SDF production | decreased number of spores | delayed gene expression | delayed culmination
DBS0304815grlA-/ [act15]: grlA: GFPgrlAaberrant tip formation
DBS0236112grlE-grlEabolished SDF production | aberrant gamma-aminobutyric acid signaling pathway | decreased sporulation
DBS0236113grlE-grlEdelayed aggregation | aberrant gene expression | decreased chemotaxis to cAMP
DBS0238865grlJ-grlJaberrant spore morphology | decreased spore viability | increased slug size | precocious development | decreased fruiting body size | precocious gene expression
DBS0238866grlJ-/ [act15]: grlJ: GFPgrlJwild type
DBS0238686grpA-grpAdecreased spore germination | abolished protein secretion
DBS0238687grpA-/ [act15]: grpA-FLAGgrpAwild type
ARK200gskA-gskAincreased gene expression | decreased gene expression | decreased chemotaxis to cAMP | abolished streaming | decreased sporulation
DBS0236114gskA-gskAdecreased slug migration | aberrant sorus morphology | decreased stalk length
HM338gskA-gskAprecocious aggregation | decreased prespore cell differentiation | aberrant fruiting body morphology | increased prestalk cell differentiation | decreased sporulation
DBS0349800gskA-/ [ecmA]: LacZgskAaberrant gene expression
DBS0349801gskA-/ [ecmB]: LacZgskAaberrant gene expression
DBS0266891gtaC-gtaCabolished stalk cell differentiation in vitro | aberrant streaming | decreased aggregate size | aberrant prestalk B cell differentiation
DBS0236120gxcA-gxcAdecreased chemoattractant-mediated F-actin polymerization | delayed development | decreased positive regulation of Rac GTPase activity
DBS0236121gxcB-gxcBdecreased exocytosis | aberrant cytoskeleton organisation | delayed development
DBS0238825gxcDD-gxcDDaberrant streaming | delayed development
DBS0236129hbx2-hbx2wild type
DBS0236130hbx2-hbx2wild type
DBS0236131hbx2-/ warA-hbx2 | warAincreased basal disc size | development arrests at mound stage | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0236152hcpAΔC-GFPhcpAdecreased growth rate in suspension | abolished growth on bacterial plates
DBS0236153hcpA-hcpAdecreased growth rate in suspension at low temperature
DBS0236157hcpB-hcpBwild type
DBS0236159hcpBdeltaC: GFPhcpBdecreased growth rate in suspension
DBS0305109hdaB-hdaBdecreased sporulation | decreased histone deacetylase activity
HM1012helC-helCdecreased gene expression | delayed development | aberrant fruiting body morphology
HM444helC-helCdecreased gene expression | delayed development | aberrant fruiting body morphology
DG1059helE-helEincreased slug migration
DBS0236163helF-helFincreased stalk cell differentiation | increased slug size | delayed development | increased gene silencing by RNA interference
DBS0238583hipA-hipAaberrant spore morphology | decreased spore viability | aberrant spore coat morphology
DBS0305951hipA-/ epnA-epnA | hipAaberrant spore morphology | decreased spore viability
DBS0252818hssA-hssAwild type
DBS0349776htt-httdecreased growth rate in suspension | aberrant cell separation during cytokinesis | decreased chemotaxis rate | delayed development | delayed gene expression | decreased myosin II assembly
DBS0349788htt-httaberrant aggregation | development arrests at loose aggregate stage | aberrant spore morphology | decreased spore viability | aberrant response to hypo-osmotic stress | aberrant F-actin organization | decreased number of spores | aberrant response to starvation | abolished streaming | aberrant development | multiple tips in mound | aberrant prespore cell differentiation | abolished calcium-independent cell-cell adhesion
DBS0349786htt-/ [act15]: htt: GFPhttwild type
DBS0349794ibrA-ibrAaberrant stalk formation
DBS0252699icmA-icmA-1 | icmA-2abolished sporulation | aberrant signal transduction during aggregation | abolished growth | development arrests at mound stage | abolished cell polarity | abolished streaming | aberrant cAMP wave formation | delayed gene expression | aberrant fruiting body morphology | aberrant protein localization
DBS0252702icmA-/ [act15]: TAP: YFP: rasGicmA-1 | icmA-2 | rasGabolished C-terminal protein amino acid methylation
DBS0252701icmA-/ [act15]: hICMTicmA-1 | icmA-2wild type
DBS0252700icmA-/ [act15]: icmAicmA-1 | icmA-2wild type
DBS0236421icpA-icpAaberrant mitosis | aberrant cytokinesis | aberrant protein localization
DBS0238521icpA-/ [act15]: GFP: icpA(1-1013)icpAaberrant protein localization
BS153ifkA-ifkAincreased aggregate size | precocious aggregation | decreased extracellular counting factor component(s) level | precocious gene expression
BS161ifkA-/ ifkB-ifkA | ifkBincreased aggregate size | increased cell-cell adhesion | increased cell-substrate adhesion | aberrant fruiting body morphology | multiple tips in mound
BS160ifkB-ifkBincreased gene expression
DBS0236425ino1-ino1decreased intracellular myo-inositol level | abolished growth | decreased phagocytosis | increased intracellular 2,3-bisphosphoglycerate level | multiple tips in mound
DBS0266326iplA-iplAabolished cellulose biosynthesis | abolished autophagic vacuole formation | abolished autophagic cell death
HM1038iplA-iplAabolished cAMP-induced Ca2+ influx | precocious aggregation | delayed aggregation | increased chemotaxis to arachidonic acid
DBS0252878iptA-iptAdecreased spore viability
DBS0236031kctd9-kctd9wild type
DBS0236489kif12-kif12aberrant myosin II organization | aberrant cytokinesis | aberrant protein localization
DBS0236490kif12-/ [act15]: FLAG: kif12kif12wild type
DBS0302534kif13-kif13decreased spindle stabilization | precocious spindle elongation
DBS0236494kif7-kif7aberrant cell motility
DBS0236491kil1-kil1abolished resistance to pathogenic bacteria
DBS0236492krsA-krsAdecreased chemotaxis to cAMP
DBS0238720krsA-krsAaberrant response to hyperosmotic stress | precocious culmination | abolished activation of adenylate cyclase | decreased aggregate size | decreased intracellular cAMP level | precocious gene expression | abolished streaming | decreased cell size
DBS0236493krsA-/ [act15]: GFP: krsAkrsAwild type
DBS0238721krsA-/ [act15]: GFP: krsAkrsAwild type
DBS0238722krsA-/ [act15]: GFP: krsA(K49R)krsAaberrant streaming
DBS0238723krsA-/ [act15]: GFP: krsA(T173A)krsAabolished streaming
DBS0238725krsA-/ [act15]: GFP: krsA(deltaC)krsAaberrant streaming
DBS0238724krsA-/ [act15]: GFP: krsA(deltaKinase)krsAabolished streaming
DBS0238726krsA-/ [act15]: GFP: krsA(deltaNS)krsAabolished streaming
DBS0236495ku80-ku80increased sensitivity to DNA-damaging agents
AK127lagC-tgrC1development arrests at loose aggregate stage | aberrant aggregation | increased aggregate size
DBS0236498lagD-tgrD1aberrant aggregation | aberrant cAMP signaling during aggregation | abolished streaming
DBS0236499limB-limBdecreased cell polarity | decreased cell-substrate adhesion | decreased gene expression | development arrests at mound stage | aberrant F-actin organization | aberrant cell-cell adhesion | decreased chemotaxis rate | abolished sorting to prestalk region | delayed gene expression
DBS0236502limB-/ [act15]: paxB: GFPlimB | paxBdevelopment arrests at mound stage
DBS0236500limB-/ [cotC]: limBlimBdevelopment arrests at mound stage
DBS0236501limB-/ [ecmAO]: limBlimBwild type
DBS0236729limB-/ paxB-limB | paxBdevelopment arrests at mound stage
DBS0236503limE-limEaberrant cytokinesis
DBS0236506limF-limFdecreased phagocytosis
DBS0236511lipA-lipAwild type
DBS0236512lipA-lipAwild type
DG1006lipA-lipAabolished culmination
DG1056lipB-captCaberrant fruiting body morphology
DBS0236515lis1(D327H)lis1aberrant microtubule cytoskeleton organization | increased basal phosphorylated actin level | aberrant Golgi localization
DBS0236516lrrA-lrrAdecreased cell polarity | increased aggregate size | decreased cell-substrate adhesion | increased basal F-actin level | decreased spore viability | abolished chemotaxis | decreased gene expression | development arrests at mound stage | abolished aggregation | aberrant cell morphology | delayed gene expression
DBS0236517lst8-lst8decreased F-actin polymerization | aberrant activation of adenylate cyclase activity | decreased chemotaxis rate | abolished aggregation | decreased myosin II assembly
AD60lvsA-lvsAaberrant contractile vacuole organization and biogenesis | abolished cytokinesis | decreased pinocytosis | aberrant response to hypo-osmotic stress | decreased phagocytosis | increased cell-substrate adhesion
AD63lvsA-lvsAabolished cytokinesis | abolished cAMP-induced Ca2+ influx
DBS0236521lvsB-lvsBincreased secretion of lysosomal enzyme | increased lysosome size | increased exocytosis | aberrant post-lysosome organization and biogenesis | increased pinocytosis
DBS0236522lvsC-lvsCwild type
DBS0236523lvsD-lvsDwild type
DBS0236524lvsE-lvsEwild type
DBS0236525lvsF-lvsFwild type
DBS0236536malA-malAwild type
HMW404manA-manAabolished aggregation
DBS0236543mekA-mekAdecreased aggregate size | precocious development
DBS0238098mekA-/ ppp4C-mekA | ppp4cdecreased aggregate size
DBS0238109mekA-/ ppp4C-/ [act15]: FLAG: pppCppp4cdecreased aggregate size | precocious development
DBS0236542mekA-/ smkA-mekA | smkAdecreased aggregate size
DBS0266843mgp1-mgp1aberrant contractile vacuole organization and biogenesis | increased phototaxis | increased filopodium formation | decreased cell motility | decreased fruiting body size | abolished streaming | decreased stalk width | decreased stalk length
DBS0266846mgp1-/ mgp2-mgp1 | mgp2aberrant contractile vacuole organization and biogenesis | increased filopodium formation | aberrant culmination | decreased cell motility | decreased phototaxis | decreased stalk length
DBS0266844mgp2-mgp2increased aggregate size | increased slug size
HS1mhcA-mhcAaberrant protein localization
HS2207mhcA-mhcAabolished cytokinesis | development arrests at mound stage
HS2206mhcA-mhcAabolished bleb formation
HK323mhcA-mhcAdecreased cell motility
DBS0266674mhcA-/ [act15]: GFP: abpC(9-148)abpC | mhcAdecreased uropod retraction | decreased pseudopod retraction
DBS0237564mhcA-/ [act15]: GFP: ctxA/ [RNAi]enlActxA | enlA | mhcAaberrant cytokinesis, contractile ring contraction
DBS0266675mhcA-/ [act15]: GFP: mhcA(E476K)mhcAdecreased pseudopod retraction
DBS0236548mhcA-/ [act15]: GFP: pats1(2087-2351)mhcA | pats1aberrant cytokinesis
DBS0236549mhcA-/ [act15]: limE(1-145): GFPlimE | mhcAincreased F-actin polymerization
DBS0238158mhcA-/ [act15]: mhcA(81-2116)mhcAdecreased growth rate | development arrests at tipped mound stage
CW0401mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A)mhcAdecreased growth rate in suspension | increased myosin II assembly
DBS0236550mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A)mhcAdecreased filopodium formation
DBS0236551mhcA-/ [act15]: mhcA(T1823D/ T1833D/ T2029D)mhcAincreased filopodium formation
DBS0238399mhcA-/ [act15]: rapA(G12V)mhcA | rapAincreased basal F-actin level | aberrant myosin II organization | increased cell polarity
DBS0236552mhcA-/ [mhcA]: mhcA(1-1224)mhcAaberrant cytokinesis | development arrests at mound stage
DBS0238157mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R689H)mhcAdecreased actin filament sliding
DBS0236547mhcA-/ [unk]: GFP: icpAicpA | mhcAaberrant protein localization
CW0371mhkA-mhkAincreased myosin II assembly
DBS0236557mhkA-/ [act15]: mhkAmhkAdecreased growth rate in suspension | development arrests at mound stage | aberrant cytokinesis | decreased myosin II assembly
CW0431mhkA-/ mhkB-/ mhkC-mhkA | mhkB | mhkCdecreased growth rate in suspension | increased myosin II assembly | aberrant cytokinesis
DBS0236556mhkA-/ mhkC-mhkA | mhkCdecreased growth rate in suspension | increased myosin II assembly | aberrant cytokinesis
CW0394mhkA/ mhkBmhkA | mhkBdecreased growth rate in suspension | increased myosin II assembly | aberrant cytokinesis
CW0166mhkB-mhkBincreased myosin II assembly
CW0403mhkC-mhkCincreased myosin II assembly | aberrant cytokinesis
DG1069mhkC-mhkCaberrant fruiting body morphology
CW0435mhkD-mhkDincreased myosin II assembly
DBS0236559midA-midAdecreased growth rate in suspension | aberrant spore morphology | decreased thermotaxis | increased intracellular glutamate level | decreased intracellular glycogen level | increased extracellular ammonia level | increased slug migration | decreased growth rate on bacterial plates | decreased cell size | decreased phototaxis
DG1020migA-migAabolished slug migration | decreased fruiting body size | aberrant fruiting body morphology
DBS0266620mipp1-mipp1aberrant inositol phosphate metabolic process | increased response to lithium
DBS0309109mipp1-/ dpoA-dpoA | mipp1aberrant inositol phosphate metabolic process | increased response to lithium
DBS0236560mkcA-mkcAdecreased gene expression
DBS0236561mkcA-/ tagB-mkcA | tagBdecreased sporulation
DBS0236562mkcA-/ tagC-mkcA | tagCdecreased sporulation
DG1101mkcB-mkcBdecreased fruiting body size
DBS0236564mkkA-mkkAprecocious culmination | decreased sorus size | increased stalk length
DG1121mkpA-mkpAabolished aggregation
DBS0236566mlcE-mlcEdecreased growth rate in suspension | aberrant cytokinesis | delayed aggregation | decreased cell motility | mislocalized gene expression | aberrant development
DBS0238058mlcE-/ [act15]: myc: mlcEmlcEwild type
DBS0236567mlcR-mlcRaberrant myosin II organization | aberrant cytokinesis | development arrests at mound stage
HS183mlkA-mlkAaberrant cytokinesis
DG1033modA-modAaberrant fruiting body morphology
DBS0266903mpl1-mpl1decreased cell motility | decreased chemotaxis to cAMP | abolished streaming | abolished aggregation
DBS0266904mpl1-/ [act15]: flag: mpl1mpl1wild type
DBS0236569mrps4-mrps4delayed aggregation | aberrant fruiting body morphology
DBS0304881mrps4-mrps4delayed aggregation
DBS0304882mtDNA-DidioMp05 | DidioMp21 | DidioMp26 | DidioMp27 | DidioMp30 | DidioMp35 | DidioMp36 | ai2a | ai2b | ai3 | ai4 | atp1 | atp6 | atp9 | cox1/ 2 | cox3 | cytB | mrpl11 | mrpl14 | mrpl16 | mrpl2 | mrpl6 | mrps12 | mrps13 | mrps14 | mrps19 | mrps2 | mrps4 | mrps7 | mrps8 | nad1 | nad11 | nad2 | nad3 | nad4 | nad4L | nad5 | nad6 | nad7 | nad9 | rnlAabolished growth | abolished aggregation
HM1463mus81-mus81wild type
DBS0236570mybB-mybBdecreased cAMP-induced cGMP pulse | decreased gene expression | decreased activation of adenylate cyclase | abolished aggregation | decreased cAMP-induced cAMP pulse
DBS0236571mybB-mybBabolished aggregation
HM388mybC-mybCdecreased SDF production | decreased gene expression | abolished culmination
DBS0236572mybE-mybEincreased slug size | abolished outer basal disc formation
DBS0237709mybE-/ [mrrA]: lacZmrrA | mybEaberrant prestalk cell differentiation
DBS0236573mybE-/ mybE: GFPmybEwild type | aberrant prestalk cell differentiation
HDT1myoA-myoAdelayed aggregation | decreased cell motility | decreased chemotaxis rate | decreased lateral pseudopod suppression
HDT2myoA-myoAincreased secretion of lysosomal enzyme
HDT5myoA-/ myoBmyoA | myoBdecreased pinocytosis | decreased growth rate in suspension | aberrant cytoskeleton organisation | increased secretion of lysosomal enzyme | decreased cell motility | decreased fruiting body size
DBS0236579myoB-myoBincreased secretion of lysosomal enzyme
DBS0236580myoB-myoBdecreased phagocytosis | delayed aggregation | decreased cell motility | decreased lateral pseudopod suppression
DBS0236583myoB-/ [AS]myoDmyoB | myoDdecreased pinocytosis | aberrant aggregation | decreased growth rate | decreased phagocytosis | decreased cell motility | decreased aggregate size
DBS0236584myoB-/ [AS]myoD/ [KD]myoCmyoB | myoC | myoDsmall pinosomes | decreased pinocytosis | aberrant aggregation | decreased growth rate | decreased phagocytosis | decreased cell motility | increased number of pinosomes | decreased aggregate size
HDT6myoB-/ myoC-myoB | myoCincreased secretion of lysosomal enzyme | decreased growth rate in suspension | aberrant cytoskeleton organisation | decreased fruiting body size
DBS0236585myoC-myoCdecreased phagocytosis
DBS0236587myoD-myoDwild type
HDT8myoF-myoFwild type
DBS0236589myoI-myoIdecreased spore germination
DBS0236592myoI-myoIdecreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology
HDT15myoI-myoIdecreased phagocytosis
HDT17myoI-myoIdecreased cell-cell adhesion | decreased protein level | decreased cell-substrate adhesion | decreased phagocytosis | decreased filopodium formation
DBS0266889myoI-/ [act15]: GFP: myoImyoIwild type
DBS0266890myoI-/ [act15]: GFP: myoI(809-1154)myoIdecreased phagocytosis
DBS0237617myoI-/ [act15]: gbpDgbpD | myoIincreased pseudopod formation | increased cell-substrate adhesion | aberrant cell morphology
HTD7myoJ-myoJwild type
DBS0349844myoK-myoKaberrant cortical actin cytoskeleton stabilization | delayed aggregation | decreased phagocytosis | aberrant engulfment during phagocytosis | decreased chemotaxis rate | aberrant cell morphology
DBS0349846myoK-/ [act15]: YFP: myoK(1-121: 262-858)myoKdecreased phagocytosis
DBS0349850myoK-/ [act15]: myoKmyoKincreased phagocytosis
DBS0349854myoK-/ [act15]: pakB(1-337: 563-852)myoK | pakBwild type
DBS0236595myoM-myoMwild type
SB12napA-napAdecreased cell-cell adhesion | decreased cell polarity | decreased cell-substrate adhesion | decreased cell motility | decreased basal F-actin level | decreased cell size | decreased phototaxis
SB14napA-/ pirA-napA | pirAdecreased basal F-actin level
HC476ncsA-ncsAincreased intracellular cAMP level | precocious gene expression | precocious development
HC477ncsA-ncsAincreased intracellular cAMP level | precocious gene expression | precocious development
DBS0304633nfaA-nfaAaberrant localization of protein to the plasma membrane | increased pseudopod formation | increased chemoattractant-mediated F-actin polymerization | increased basal F-actin level | delayed aggregation | decreased cell motility | aberrant cAMP signaling during aggregation | aberrant regulation of Ras GTPase activity | aberrant regulation of protein kinase activity | decreased chemotaxis to cAMP
DBS0304634nfaA-/ rasG-nfaA | rasGdecreased cell polarity
DBS0236604nhe1-nhe1decreased intracellular pH level | decreased cell polarity | aberrant F-actin organization | decreased chemotaxis rate
DBS0349841nhe1-/ [act15]: mhcA: GFPmhcA | nhe1aberrant protein localization
DBS0236605nhe1-/ [act15]: nhe1: HAnhe1wild type
DBS0236606nosA null (15-S-12)nosAdevelopment arrests at mound stage
DBS0236607nosA null (2E4)nosAdevelopment arrests at mound stage
DBS0235950nosA-nosAdevelopment arrests at mound stage
DBS0236608noxA-noxAabolished sporulation | aberrant development
DBS0236611noxA-/ [act15]: noxA: myc2noxAaberrant fruiting body morphology
DBS0236610noxA-/ noxBnoxA | noxBabolished sporulation | decreased superoxide production | aberrant development
DBS0236612noxB-noxBabolished sporulation | decreased superoxide production | aberrant development
DBS0236613noxC-noxCabolished sporulation | aberrant development
DBS0238849npcA-npcAwild type
DBS0236695nramp1-nramp1increased infection rate by Mycobacterium avium | increased infection rate by Legionella pneumophila | abolished iron ion transport
DBS0236696nramp1-/ [act15]: nramp1: GFPnramp1decreased infection rate by Legionella pneumophila
DBS0236697nramp1-/ [act15]: nramp1: GFPnramp1decreased infection rate by Legionella pneumophila
HM1060nsfA(A1847G, A1939T, T1977C, T2005G, A2025T, A2366T)nsfAdecreased rate of endocytosis | decreased phagocytosis | decreased F-actin polymerization at the leading edge | abolished cell motility
HM1067nsfA(A1854T, T1984A, C2131A, A2398T, T2574A)nsfAdecreased rate of endocytosis | abolished cell motility | decreased F-actin polymerization at the leading edge | decreased cell motility | increased phagocytosis
DBS0236955nxnA-nxnAdecreased culmination | decreased growth rate | delayed development | decreased chemotaxis to cAMP | decreased lysosomal enzyme activity
DBS0236702nxnA-/ [act15]: GFP: nxnB nxnA | nxnBdevelopment arrests at mound stage
DBS0236704osbA-osbAincreased slug migration | precocious development
DBS0238357p2xA-p2xAaberrant response to hypo-osmotic stress
DBS0304487p2xA-p2xAwild type
DBS0238362p2xA-/ [act15]: p2xA: GFPp2xAwild type
DBS0306169p2xA-/ p2xB-/ p2xC-/ p2xD-/ p2xE-p2xA | p2xB | p2xC | p2xD | p2xEdelayed response to hypo-osmotic stress | decreased growth rate
DBS0306166p2xB-p2xBwild type
DBS0306167p2xC-p2xCwild type
DBS0306168p2xD-p2xDwild type
DBS0304486p2xE-p2xEwild type
DBS0304465padA(1-276)padAaberrant streaming | development arrests at slug stage | delayed aggregation | aberrant stalk cell differentiation | delayed development | aberrant fruiting body morphology
DBS0236705pakA-pakAaberrant cytokinesis | delayed development
DBS0236706pakA-pakAwild type
DBS0236707pakA-/ [act15]: pakApakAwild type
DBS0236709pakB-pakBdecreased growth rate
DBS0236712pakB-/ [act15]: GFP-pak(1-600)pakBabolished cytokinesis
DBS0236710pakB-/ [act15]: GFP-pakB(1-337: 563-851)pakBabolished cytokinesis | increased pinocytosis | increased phagocytosis
DBS0236715pakB-/ pakC-pakB | pakCdecreased chemotaxis rate
DBS0236719pakC(R34C)pakCdecreased chemotaxis rate | decreased lateral pseudopod suppression
DBS0236720pakC(S466A/ P470A)pakCdecreased chemotaxis rate | decreased lateral pseudopod suppression
HC392patB-patBabolished growth on bacterial plates | abolished growth in acidic medium
DBS0236726pats1-pats1aberrant cytokinesis
DBS0236727pats1-/ [act15]: GFP: pats1(2087-2351)pats1aberrant cytokinesis
DBS0236728paxB-paxBdecreased cell-substrate adhesion | decreased gene expression | abolished slug migration | development arrests at mound stage | decreased sorting to prestalk region | aberrant fruiting body morphology
DBS0304926paxB-paxBaberrant cell separation during cytokinesis | decreased cell-substrate adhesion | aberrant cytokinesis | decreased cell motility
DBS0304930paxB-/ [act15]: GFP: paxBpaxBwild type
DBS0236730paxB-/ [ecmA]: paxB: GFPpaxBdecreased sorting to prestalk region
DBS0236732paxB-/ [pspA]: paxB: GFPpaxBdecreased sorting to prestalk region
DBS0304929paxB-/ mhcA-mhcA | paxBaberrant cytokinesis
DBS0236733pcp-pcpwild type
DBS0236734pde4-pde4decreased culmination | delayed slug formation | delayed culmination
DBS0236735pde4-/ [act15]: pde4: GFPpde4wild type
DBS0236736pdeD-pdeDdecreased cAMP-induced Ca2+ influx | delayed cAMP-induced Ca2+ influx | decreased Ca2+-induced Ca2+ influx
UK7pdsA-pdsAdecreased 3',5'-cyclic-AMP phosphodiesterase activity | abolished aggregation
DBS0236741pefA-pefAwild type
DBS0236742pefA-/ pefB-pefA | pefBwild type
DBS0236744pefB-pefBwild type
DBS0236745pefB-/ cybA-cybA | pefBwild type
DBS0236746pefB-/ noxA-noxA | pefBwild type
DBS0236747pefB-/ noxA-/ [act15]: pefBnoxA | pefBaberrant development
DBS0236748pefB-/ noxB-noxB | pefBwild type
DBS0236749pefB-/ noxC-noxC | pefBabolished sporulation | aberrant development
HW260pgtA-pgtAincreased cell size
DBS0236752phdA-phdAdecreased basal F-actin level | decreased aggregate size | decreased chemotaxis rate | decreased fruiting body size
DBS0236753phdA-/ [act15]: phdAphdAwild type
DBS0236754phdA-/ [act15]: phdA: GFPphdAwild type
DBS0304869phg1A-/ [act15]: phg1a(1-276): phg1b(221-587)phg1a | phg1bdecreased phagocytosis
DBS0304868phg1A-/ [act15]: phg1bphg1a | phg1bincreased secretion of lysosomal enzyme | decreased cell-substrate adhesion | decreased phagocytosis
DBS0304870phg1A-/ [act15]: phg1b(1-220): phg1a(277-642)phg1a | phg1bdecreased phagocytosis
DBS0304872phg1A-/ phg1b-phg1a | phg1bincreased secretion of lysosomal enzyme | decreased cell-substrate adhesion | decreased phagocytosis | decreased growth rate | development arrests at tipped mound stage | abolished culmination
DBS0236755phg1a-phg1aincreased secretion of lysosomal enzyme | decreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | abolished resistance to pathogenic bacteria | decreased growth rate | development arrests at slug stage
DBS0236757phg1a-/ [act15]: kil1kil1 | phg1awild type
DBS0304866phg1b-phg1bincreased secretion of lysosomal enzyme | decreased phagocytosis | decreased growth rate | abolished culmination
DBS0236758phg2-phg2decreased cell-substrate adhesion | decreased phagocytosis | aberrant cytokinesis | aberrant F-actin organization | decreased cell motility | aberrant response to nutrients | aberrant cell morphology | precocious development | precocious gene expression
DBS0238400phg2-phg2increased filopodium formation | increased basal F-actin level | increased cell-substrate adhesion | decreased chemotaxis to cAMP | aberrant cell morphology | increased phagocytosis
DBS0236760phg2-/ [act15]: GFP: phg2(199-1389)phg2decreased phagocytosis
DBS0237615phg2-/ [act15]: gbpDgbpD | phg2increased pseudopod formation | aberrant cell morphology | abolished chemotaxis to cAMP
HG1648phgA-phgAaberrant contractile vacuole organization and biogenesis | aberrant response to hypo-osmotic stress
DBS0236761phgA-/ [act6]: GFP: lvsAlvsA | phgAaberrant protein localization
DBS0236762phlp1-phlp1decreased growth rate in suspension | decreased cAMP-induced cGMP pulse | aberrant regulation of protein modification | abolished chemotaxis | abolished aggregation | decreased growth rate on bacterial plates | decreased cAMP-induced cAMP pulse | aberrant protein localization
DBS0236763phlp1-/ [OE]: phpl1phlp1wild type
DBS0236764phlp3-phlp3wild type
HW288phyA-phyAabolished sporulation | decreased peptidyl-proline hydroxylation | abolished stalk formation | abolished culmination
DBS0266771phyA-/ [ecmA]: phyA(D132N): mycphyAdecreased peptidyl-proline hydroxylation
DBS0266770phyA-/ [ecmA]: phyA(R276A): mycphyAabolished peptidyl-proline hydroxylation | abolished culmination
DBS0236767pia-piaAaberrant activation of adenylate cyclase activity
DBS0236769piaA(G917D)/ [act15]: piaApiaAdelayed aggregation
DBS0236770piaA-piaAaberrant cytokinesis
DBS0236771piaA-piaAabolished aggregation | decreased myosin II assembly
DBS0304637piaA-piaAdecreased cell polarity | decreased cell motility | decreased chemotaxis rate | aberrant protein tyrosine phosphorylation
HSB1piaA-piaAdecreased activation of adenylate cyclase | abolished aggregation
DBS0236772pikA-pikAwild type
DBS0236766pikA-/ pikB-pikA | pikBaberrant negative chemotaxis | decreased cell motility | decreased chemotaxis to folate | decreased cAMP-induced cAMP pulse
DBS0236773pikA-/ pikB-pikA | pikBabolished CRAC localization to the plasma membrane | increased intracellular cAMP level | aberrant adaptation of adenylate cyclase | abolished SDF production | delayed aggregation | abolished growth in suspension | multiple tips | abolished streaming | decreased cAMP-induced cAMP pulse
HM1141pikA-/ pikB-pikA | pikBdecreased cell motility
DBS0252703pikA-/ pikB-/ pikC-pikA | pikB | pikCincreased cell motility
HM1200pikA-/ pikB-/ pikC-/ pikF-/ pikG-pikA | pikB | pikC | pikF | pikGaberrant aggregation | decreased growth rate in bacterial suspension | decreased protein tyrosine phosphorylation | decreased cell motility
HM1284pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pikH-pikA | pikB | pikC | pikF | pikG | pikHdecreased cell motility
HM1295pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pten-pikA | pikB | pikC | pikF | pikG | ptenaberrant aggregation | decreased growth rate | decreased cell motility
DBS0238073pikA-/ pikB-/ plaA-pikA | pikB | plaAdecreased chemoattractant-mediated F-actin polymerization | abolished chemotaxis | delayed aggregation
DBS0236774pikB-pikBwild type
DBS0236776pikC-pikCwild type
DBS0236777pikD1pikDabolished slug migration | delayed aggregation | decreased number of spores | decreased aggregate size | aberrant fruiting body morphology
DBS0236778pikE-pikEwild type
SB16pirA-pirAincreased cell motility | decreased cell size
SB3pirA-pirAincreased pseudopod formation | increased basal F-actin level | increased cell size | decreased cell motility
DBS0236782pkaC-/ gdt1-gdt1 | pkaCincreased gene expression | abolished aggregation
HTY217pkaR(A31T)pkaRprecocious development
DBS0235411pkaR-pkaRaberrant response to lithium | aberrant response to valproic acid | decreased fruiting body size
DBS0236785pkbA-/ pkgB-pkbA | pkgBabolished growth | decreased chemotaxis rate | abolished aggregation
DBS0304640pkbA-/ pkgB-pkbA | pkgBabolished growth
DBS0236786pkgB-pkgBabolished SDF production | development arrests at mound stage
DBS0304638pkgB-pkgBdecreased cell-substrate adhesion | development arrests at mound stage | decreased chemotaxis rate | increased cell motility
DBS0236787pkgB-/ [act15]: pkbApkbA | pkgBwild type
DBS0236789pkgB-/ [act15]: pkgB(K182M)pkgBdevelopment arrests at mound stage
DBS0236790pkgB-/ [gbfA]: pkbApkbA | pkgBwild type
DBS0236791pkgB-/ [gbfA]: pkgBpkgBwild type
DBS0238068plaA-plaAabolished aggregation
DBS0238067plaA-plaAabolished aggregation
DG1067plbG-plbGdecreased stalk width | decreased stalk length
HAD236plc-plcdecreased activation of protein kinase B | decreased CRAC localization to the plasma membrane | aberrant chemotaxis to cAMP | abolished aggregation | decreased localization of protein to the cytoplasm
HD1.19plc-plcaberrant negative chemotaxis
HD10plc-plcwild type
DBS0267125plc-/ [OE]: dagA(PH): GFP/ [OE]: plcdagA | plcincreased CRAC localization to the plasma membrane | decreased chemotaxis to cAMP | aberrant protein localization
DBS0236796pldB-pldBprecocious aggregation
DBS0236797pldB-/ [act15]: pldB: GFPpldBabolished aggregation
DBS0236799plip-plipdelayed aggregation
DBS0236820ponA-ponAprecocious aggregation | decreased lateral pseudopod traction | decreased actin nucleation on plasma membranes | aberrant development
DBS0236821ponA-ponAprecocious aggregation | decreased lateral pseudopod traction | decreased actin nucleation on plasma membranes | aberrant development
DG1057potA-potAaberrant fruiting body morphology
DBS0236824ppk1-ppk1decreased phagocytosis | decreased fruiting body size | decreased growth rate on bacterial plates | delayed culmination | decreased sporulation
DBS0236825ppk1-/ [act15]: ppk1ppk1wild type
DBS0238099ppp4C-ppp4cdevelopment arrests at mound stage | delayed development
DBS0238110ppp4C-/ [act15]: smkAppp4c | smkAdevelopment arrests at mound stage | delayed development
DBS0238033proC-proCdecreased cell polarity | increased lateral pseudopod formation | decreased chemotaxis rate
DBS0238034proC-/ [unk]: FLAG: proCproCwild type
DBS0266716pscA-pscAwild type
HOK2psiA-psiAabolished prespore cell division
DBS0236021psiM-psiMwild type
DBS0236022psiM-psiMwild type
DBS0236828pslA-pslAabolished gene expression | abolished sporulation | abolished stalk cell differentiation in vitro | decreased sorus size | increased aggregate size | increased stalk length | mislocalized gene expression
DBS0236829psmC1-psmC1curly fingers | increased resistance to spectinomycin | abolished slug migration | increased cell size
DBS0302352psrA-psrAdecreased culmination | increased protein phosphorylation | delayed development | delayed gene expression | increased protein kinase activation
DBS0302356psrA-/ [act15]: FLAG: gskAgskA | psrAincreased protein kinase activation
DBS0302353psrA-/ [act15]: ecmA: lacZpsrAaberrant gene expression
DBS0302354psrA-/ [act15]: ecmB: lacZpsrAaberrant gene expression
DBS0302357psrA-/ [act15]: gskA(K84M/ K85M)gskA | psrAdecreased culmination | decreased gene expression | delayed development
DBS0302355psrA-/ [act15]: psrApsrAwild type
HM1289pten-ptendecreased cell motility
DBS0236830pten-ptenabolished CRAC localization to the plasma membrane | decreased F-actin polymerization | increased pseudopod formation | decreased growth rate | increased F-actin polymerization | increased lateral pseudopod formation | decreased cell motility | increased CRAC localization to the plasma membrane | decreased chemotaxis to cAMP | abolished aggregation | decreased lateral pseudopod suppression
DBS0236831pten-/ [act15]: GFP: pten-ptenwild type
DBS0236832ptpA1-ptpA1-1decreased prespore cell differentiation | precocious development | increased prestalk O cell differentiation
DBS0236833ptpB-ptpBincreased slug size
DBS0236834ptpC+/ -ptpCaberrant cytokinesis | decreased growth rate
DBS0236835pufA-pufAprecocious development | aberrant fruiting body morphology
DBS0304391pyk3-pyk3increased gene expression | decreased gene expression | increased prespore cell differentiation | delayed culmination
DBS0304393pyk3-/ [act15]: T7: pyk3pyk3wild type
DBS0236836pykA-pykAdecreased growth rate | abolished aggregation
DBS0236837pyr56-pyr56uracil auxotroph | increased resistance to 5-fluoroorotic acid (5-FOA)
DBS0236838pyr56-pyr56uracil auxotroph | increased resistance to 5-fluoroorotic acid (5-FOA)
DBS0236839qkgA-qkgA-1 | qkgA-2increased aggregate size | delayed aggregation | increased growth rate
DBS0236841racB-racBdecreased chemoattractant-mediated F-actin polymerization | delayed aggregation | decreased basal F-actin level | decreased chemotaxis rate | aberrant fruiting body morphology | decreased myosin II assembly
DBS0236842racC-racCdecreased chemotaxis rate | aberrant cell morphology | aberrant protein localization
DBS0237191racC-/ [act15]: CFP: racCracCincreased chemoattractant-mediated F-actin polymerization
DBS0236843racF2-racF2increased aggregate size | increased cell-cell adhesion | decreased sexual fusion
DBS0236849racG-racGdecreased cell motility
DBS0236850racH-racHdecreased exocytosis | aberrant protein localization
DBS0266936rapgap1-rapgap1decreased positive regulation of Rap GTPase activity | increased basal F-actin level | increased cell-substrate adhesion | decreased cell motility | decreased myosin II assembly
DBS0266937rapgap1-/ [act15]: GFP: rapgap1rapgap1decreased cell-substrate adhesion | increased myosin II assembly | increased basal F-actin level | increased lateral pseudopod formation | increased cell motility | increased positive regulation of Rap GTPase activity
DBS0236852rasB-rasBdecreased growth rate
DBS0236853rasC-/ AX2rasCdecreased activation of protein kinase B | decreased cell motility | abolished aggregation
DBS0236854rasC-/ JH10rasCdecreased activation of protein kinase B | aberrant gene expression | abolished aggregation | abolished chemotaxis to cAMP
DBS0237614rasC-/ [act15]: gbpDgbpD | rasCincreased cell-substrate adhesion | aberrant cell morphology
DBS0236855rasC-/ dmpA-dmpA | rasCabolished streaming
DBS0236856rasC-/ pikD1pikD | rasCdecreased activation of protein kinase B | increased chemotaxis to cAMP | aberrant gene expression | abolished aggregation | increased cell polarity | aberrant fruiting body morphology
DBS0236857rasC-/ rasD-rasC | rasDabolished aggregation
DBS0236858rasC-/ rasG-rasC | rasGdecreased gene expression | abolished growth | abolished protein kinase B activation | decreased growth rate | decreased activation of adenylate cyclase | decreased cell motility | abolished aggregation | delayed gene expression | abolished chemotaxis to cAMP | abolished GTP-gamma-S-stimulated guanylyl cyclase activity
DBS0266697rasC-/ rasG-/ [act15]: carAcarA-1 | carA-2 | rasC | rasGabolished activation of Rap GTPase activity | abolished growth | decreased growth rate | abolished protein kinase B activation | decreased activation of adenylate cyclase | abolished cAMP-induced cGMP pulse | abolished chemotaxis to cAMP
DBS0236859rasD(G12T)rasDdevelopment arrests at mound stage | development arrests at tipped mound stage
DBS0236860rasD-rasDaberrant thermotaxis | aberrant phototaxis
DBS0236862rasG-/ AX2rasGdecreased activation of protein kinase B | decreased cAMP-induced cGMP pulse | decreased gene expression | delayed aggregation | delayed gene expression
IR15rasG-/ AX2rasGincreased cell size | decreased growth rate
IR17rasG-/ AX3rasGaberrant cytokinesis | increased cell size | decreased cell motility
DBS0236863rasG-/ JH10rasGdecreased activation of protein kinase B | decreased cAMP-induced cGMP pulse | decreased gene expression | abolished activation of Rap GTPase activity | delayed aggregation | delayed gene expression
DBS0236864rasG-/ [rasG]: rasBrasB | rasGdecreased growth rate in suspension
DBS0236872rasS-rasSdecreased cell polarity
DBS0236873rasS-rasSdecreased growth rate in liquid medium on solid sufaces | aberrant cytoskeleton organisation | decreased rate of endocytosis | increased basal F-actin level | abolished growth in suspension | increased cell motility
DBS0236874rasZ-rasZwild type
DBS0236877rblA-rblAincreased sorting to prestalk region | precocious development | increased prestalk cell differentiation in response to DIF-1 | decreased cell size
DBS0236878rbrA-rbrAincreased gene expression | decreased gene expression | development arrests at slug stage | mislocalized gene expression | decreased sorting to prestalk region | decreased phototaxis | decreased sporulation
DBS0236879rbrA-/ [unk]: rbrArbrAwild type
DBS0236880rckA-rckAdelayed slug formation | increased aggregate size | precocious aggregation | delayed gene expression | increased chemotaxis rate
DBS0236885rckA-/ [act15]: myc: rckArckAdelayed development | decreased chemotaxis rate
DBS0236881rckA-/ [act15]: myc: rckA(C551A)rckAdelayed slug formation | decreased chemotaxis rate
DBS0236882rckA-/ [act15]: myc: rckA(E510G)rckAwild type | decreased chemotaxis rate
DBS0236883rckA-/ [act15]: myc: rckA(E510G/ N511A)rckAdelayed slug formation | decreased chemotaxis rate
DBS0236884rckA-/ [act15]: myc: rckA(K867A)rckAdevelopment arrests at mound stage | decreased chemotaxis rate
FR17rdeA-rdeAprecocious aggregation | decreased aggregate size | precocious development | precocious gene expression | aberrant fruiting body morphology
FR17rdeA-rdeAprecocious aggregation | decreased aggregate size | precocious development | precocious gene expression | aberrant fruiting body morphology
DBS0236886rdeA-/ [act15]: rdeArdeAwild type
DBS0236887recA-recAincreased sensitivity to mitomycin C (MMC) | increased sensitivity to UV light | increased sensitivity to H2O2 (peroxide)
DBS0266664redA-redAdevelopment arrests at mound stage | aberrant mound color
DG1047redA-redAdevelopment arrests at mound stage | aberrant mound color
DBS0236889regA-regAincreased resistance to cisplatin | aberrant chemotaxis to cAMP | aberrant fruiting body morphology
HM332regA-regAdecreased lateral pseudopod suppression
HR45regA-regAaberrant fruiting body morphology
DBS0235706regA-/ [act15]: dhkK(D1125N)dhkK | regAprecocious development | aberrant fruiting body morphology
DBS0235708regA-/ [act15]: dhkK(H825Q)dhkK | regAprecocious development | aberrant fruiting body morphology
DBS0236891regA-/ tagB-regA | tagBdecreased sporulation
DBS0236892regA-/ tagC-regA | tagCdecreased sporulation
DBS0266818repB(1-754)repBincreased sensitivity to DNA-damaging agents
HM1351rev3-rev3increased sensitivity to cisplatin
HM1451rev3-/ xpf-rev3 | xpfincreased sensitivity to cisplatin
DBS0236893rgaA-rgaAaberrant cytokinesis | abolished sorting to prestalk region | abolished stalk cell differentiation | abolished culmination | decreased sporulation
DBS0236894rhgA-rhgAwild type
DBS0236902ripA-/ [unk]: ripA(K680E/ R681E)ripAdecreased chemotaxis rate | aberrant development
DBS0236901ripA-/ [unk]ripAripAwild type
DBS0236903rnpA-rnpAincreased gene expression
DBS0238225rpkA-rpkAdevelopment arrests at loose aggregate stage | aberrant response to conditioned medium factor | decreased cell polarity | decreased cell motility | abolished aggregation
DBS0236875rtoA-rtoAdecreased rate of endocytosis | decreased infection rate by Legionella pneumophila | increased prestalk cell differentiation | delayed culmination
DBS0236911rtoA-rtoAdelayed development
DBS0236914rzpA-rzpAaberrant aggregation | decreased slug migration | increased aggregate size | increased gene expression | decreased gene expression | delayed development
DBS0236915rzpA-OErzpAincreased gene expression | decreased gene expression | delayed culmination
DBS0236921sadA-sadAabolished cell-substrate adhesion | decreased phagocytosis | aberrant cytokinesis | aberrant F-actin organization | increased growth rate | aberrant cell morphology
DBS0349790sadA-/ [act15]: sadA(1-923): GFPsadAdecreased cell-substrate adhesion
DBS0349792sadA-/ [act15]: sadA(S924A/ S925A): GFPsadAwild type
DBS0349791sadA-/ [act15]: sadA(S924E/ S925E): GFPsadAdecreased cell-substrate adhesion
DBS0236922sadA-/ [act15]: sadA: GFPsadAwild type
DBS0236924scrA-scrAdecreased basal F-actin level | increased lateral pseudopod formation | multiple tips | decreased fruiting body size | precocious development | decreased cell size
IR46scrA-scrAdecreased cell motility | decreased cell size
IR48scrA-scrAdecreased growth rate | aberrant cytokinesis
DBS0236925scrA-scrAincreased filopodium formation
DBS0237774scrA-/ [unk]: scrA(97-443): GFPscrAaberrant cytoskeleton organisation | increased cell size | aberrant cytokinesis | decreased chemotaxis to cAMP
DBS0237779scrA-/ [unk]: scrA: GFPscrAwild type
SB18scrA-/ napA-napA | scrAdecreased cell motility | decreased basal F-actin level
SB7scrA-/ pirA-pirA | scrAdecreased cell size
HM1163sec1(M213K, E258G, M427V, K527I, T541N, F558S, N581D)sec1abolished cell motility
DBS0306234secG-secGdecreased cell-substrate adhesion | decreased chemotaxis rate
DBS0236928set1-set1precocious aggregation | abolished histone H3-K4 methylation | precocious gene expression
HG1132sevA-sevAwild type
DG1008sfbA-sfbAdecreased fruiting body size
SA576sgkA-sgkAincreased sensitivity to cisplatin | increased sensitivity to carboplatin | decreased growth rate
HM1093sgkA-/ sgkB-sgkA | sgkBincreased sensitivity to cisplatin | increased sensitivity to carboplatin | decreased growth rate
HM1091sgkB-sgkBincreased sensitivity to cisplatin | increased sensitivity to carboplatin | decreased growth rate
SA555sglA-sglAaberrant cytoskeleton organisation | increased stalk width | increased resistance to cisplatin | increased aggregate size | decreased gene expression | abolished slug migration | decreased cell motility | decreased chemotaxis rate | decreased fruiting body size | decreased lateral pseudopod suppression | decreased sporulation
SA554sglA-sglAdelayed aggregation | decreased aggregate size
DBS0236934shkA-shkAaberrant aggregation | decreased cell polarity | aberrant F-actin organization | decreased phagocytosis | aberrant cytokinesis | decreased chemotaxis rate | decreased fruiting body size
DBS0236935sibA-sibAdecreased cell-substrate adhesion | decreased phagocytosis
DBS0302653sibC-sibCdecreased phagocytosis
DBS0236936sigB-sigBwild type
DBS0236937sigD-sigDwild type
DBS0236938smkA-smkAaberrant cytokinesis | delayed development | decreased chemotaxis rate | decreased myosin II assembly
HDB7YAsmlA-smlAdecreased secretion of lysosomal enzyme | decreased cell-cell adhesion | decreased cAMP-induced cGMP pulse | decreased GTP-gamma-S-stimulated guanylyl cyclase activity | increased cAMP-induced cAMP pulse | increased resistance to cisplatin | decreased protein level | increased basal F-actin level | increased myosin II assembly | increased protein level | increased extracellular counting factor component(s) level | increased cell motility | decreased fruiting body size | increased intracellular counting factor component(s) level
DBS0302657smlA-/ cnrN-cnrN | smlAdecreased fruiting body size
DBS0236940smlA-/ ctnA-ctnA | smlAincreased cell-cell adhesion
DBS0304496smlA-/ sslA1(CR11)smlA | sslA1increased fruiting body size
DBS0302523sodC-sodCaberrant cytokinesis
DBS0302524sodC-sodCdecreased positive regulation of Ras GTPase activity | decreased chemoattractant-mediated F-actin polymerization | aberrant aggregation | increased localization of protein to the plasma membrane | aberrant localization of protein to the plasma membrane | increased basal F-actin level | decreased chemotaxis rate | aberrant cell morphology
HL351spiA-spiAdecreased spore viability
DBS0236943spkA-1-/ spkA-2-spkA-1 | spkA-2decreased cell polarity | decreased cell-substrate adhesion | aberrant cytokinesis | decreased chemotaxis rate | decreased aggregate size | aberrant cell morphology | decreased fruiting body size
DBS0236944spkA-1-/ spkA-2-/ [act15]: spkA: FLAGspkA-1 | spkA-2aberrant aggregation | decreased cell polarity | aberrant F-actin organization | decreased chemotaxis rate
DBS0236945splA-splAaberrant spore morphology | increased sorus size | translucent sorus | spores inviable | decreased stalk length
DBS0236947spnA-spnAabolished prespore cell differentiation | development arrests at mound stage | abolished prestalk cell differentiation | aberrant development
DBS0236948spnA-/ arkA-arkA | spnAdecreased gene expression | increased sorus size | decreased stalk length | delayed gene expression
DBS0236949sr-srdecreased intracellular pteridine level | decreased spore viability | decreased cytochrome C oxidase activity | decreased growth rate
DBS0236950srfA(1-8): lacZsrfAdecreased slug migration | aberrant fruiting body morphology | delayed culmination
DBS0236951srfA-srfAaberrant spore morphology | aberrant spore coat morphology | decreased spore viability | decreased gene expression
DBS0266691srfB-srfBaberrant cAMP signaling | precocious aggregation | decreased growth rate | increased pinocytosis | aberrant cytokinesis | increased lateral pseudopod formation | abolished streaming | precocious gene expression
DBS0304409srsA-srsAdecreased gene expression | increased gene expression | increased aggregate size | delayed aggregation
DBS0304497sslA1-/ sslA1(CR11)sslA1decreased cAMP-induced cGMP pulse | increased fruiting body size | decreased cAMP-induced cAMP pulse
DBS0236952stkA-stkAincreased gene expression | decreased gene expression | increased prestalk cell differentiation | aberrant fruiting body morphology | delayed gene expression
HM1157stlA-stlAwild type
HM1154stlB-stlBabolished prestalk B cell differentation | abolished DIF production | decreased prestalk O cell differentiation | abolished lower cup formation | abolished outer basal disc formation | decreased prestalk cell differentiation | aberrant fruiting body morphology
DBS0304547svkA-svkAdelayed cell separation during cytokinesis | aberrant cytokinesis | aberrant fruiting body morphology
DBS0236958t96AregAdecreased spore germination | precocious sporulation
AK1200tagA-tagAabolished SDF production | aberrant fruiting body morphology
AK859tagA-tagAdecreased spore viability | abolished SDF production | multiple tips in mound | increased prestalk A cell differentiation
AK1201tagA-/ [ecmA]: GFPtagAabolished sorting to prestalk region
AK228tagB-tagBdevelopment arrests at mound stage | abolished DIF production | aberrant prestalk A cell differentiation
DBS0236974tagB-/ psmA1-psmA1 | tagBabolished sporulation
DBS0236975tagC-tagCdevelopment arrests at mound stage | spores inviable
DBS0236976talA-talAdecreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology
HG1666talA-talAdecreased cell-cell adhesion | decreased cell-substrate adhesion | aberrant cytokinesis | decreased growth rate | decreased phagocytosis
HG1663talA-talAdecreased cell-substrate adhesion
HG1664talA-talAdecreased growth rate | decreased phagocytosis
HG1665talA-talAdecreased cell-cell adhesion | aberrant cytokinesis
DBS0304585talA-/ [act15]: FLAG: talBtalA | talBdecreased cell-substrate adhesion
DBS0237616talA-/ [act15]: gbpDgbpD | talAincreased pseudopod formation | increased cell-substrate adhesion | aberrant cell morphology
DBS0238395talA-/ [act15]: rapA(G12V)rapA | talAincreased cell-substrate adhesion
DBS0304581talA-/ talB-talA | talBdevelopment arrests at loose aggregate stage | abolished cell-substrate adhesion | aberrant cytokinesis | abolished cell motility
DBS0304582talA-/ talB-/ [act15]: FLAG: talBtalA | talBwild type
HKT104talB-talBdecreased slug migration | decreased cell motility | development arrests at tipped mound stage | increased protein level
DBS0302472talB-talBabolished autophagic vacuole formation | abolished autophagic cell death
DBS0304586talB-/ [act15]: talA: GFPtalA | talBaberrant fruiting body morphology
DBS0304820tgrB1-tgrB1development arrests at loose aggregate stage | delayed sporulation | decreased sporulation
DBS0304821tgrC1-tgrC1abolished sporulation | development arrests at loose aggregate stage in the presence of EGTA
AK244tipA-tipAincreased aggregate size | decreased gene expression | development arrests at mound stage | multiple tips
JS64tipA-/ tipB-/ [act15]: lacZtipA | tipBincreased aggregate size | development arrests at mound stage | multiple tips in mound
JS98tipA-/ tipC-/ [ecmA]: lacZtipA | tipCdevelopment arrests at loose aggregate stage
JS128tipA-/ tipD-/ [ecmA]: lacZtipA | tipDdevelopment arrests at loose aggregate stage
JS56tipB-tipBincreased aggregate size | development arrests at mound stage | multiple tips | multiple tips in mound
JS99tipB-/ tipC-/ [ecmA]: lacZtipB | tipCdevelopment arrests at tipped mound stage | multiple tips in mound
JS129tipB-/ tipD-/ [ecmA]: lacZtipB | tipDdevelopment arrests at tipped mound stage | multiple tips in mound
JS55tipC-tipCincreased aggregate size | development arrests at mound stage | multiple tips
JS130tipC-/ tipD-/ [ecmA]: lacZtipC | tipDdevelopment arrests at loose aggregate stage
JS93tipD-tipDincreased aggregate size | development arrests at mound stage | multiple tips
DBS0304519tirA-tirAdecreased growth rate | increased infection rate by Legionella pneumophila
DBS0237017torA-torAdelayed aggregation | decreased growth rate | decreased cell motility | decreased chemotaxis rate
DBS0237018torA-/ [act15]: torA: GFPtorAabolished growth
DBS0237924triA-triAdecreased cell-cell adhesion | aberrant streaming | increased stalk width | aberrant upper cup formation | decreased spore viability | aberrant culminant morphology | decreased spore size | decreased cell fate determination | increased number of aggregates | decreased cell fate commitment
DBS0237996triA-triAaberrant culminant morphology
DBS0237997triA-triAaberrant culminant morphology
DBS0237998triA-/ [act15]: GFPtriAaberrant culminant morphology
DBS0237999triA-/ [ecmAO]: lacZ: [ecmAO]: gustriAincreased prestalk O cell differentiation
DBS0238001triA-/ [psA]: lacZ: [psA]: gustriAincreased prespore cell differentiation
DBS0237022tsg101-tsg101decreased fruiting body size
DBS0302370tsuA-tsuAincreased period of cAMP wave formation | aberrant chemotaxis to folate | aberrant chemotaxis to cAMP | delayed aggregation | decreased aggregate size | abolished cell polarity | decreased fruiting body size
DBS0302383tsuA-/ [unk]: tsuA(1-1774): YFPtsuAabolished localization of protein to the microtubule organizing center | decreased aggregate size | abolished localization of protein to microtubules | decreased fruiting body size
DBS0302385tsuA-/ [unk]: tsuA(1-260): YFPtsuAabolished localization of protein to the microtubule organizing center | abolished localization of protein to microtubules | decreased aggregate size | decreased fruiting body size
DBS0302384tsuA-/ [unk]: tsuA(1774-2247): YFPtsuAabolished localization of protein to the microtubule organizing center | abolished localization of protein to microtubules | decreased aggregate size | decreased fruiting body size
DBS0302382tsuA-/ [unk]: tsuA(K34R): YFPtsuAdecreased aggregate size | decreased fruiting body size
DBS0302381tsuA-/ [unk]: tsuA: YFPtsuAwild type
DBS0237024ubcB-ubcBdevelopment arrests at mound stage | multiple tips
DBS0306165ube2t-ube2tincreased sensitivity to cisplatin
DBS0237025ubpA-ubpAdecreased gene expression | decreased chemotaxis rate | abolished aggregation | decreased cAMP-induced cAMP pulse
DBS0237026ubpB-ubpBaberrant sorus morphology | increased gene expression | decreased gene expression | precocious development
DBS0237027ufc1-ufc1wild type
DBS0266763ugpB-/ DH1ugpBdecreased stalk length
DBS0266764ugpB-/ HMXugpBabolished cellulose biosynthesis | decreased autophagic vacuole formation | aberrant cell morphology
DBS0237031vacA-vacAwild type
DBS0237032vacB-vacBdecreased exocytosis
DBS0237034vasP-vasPabolished filopodium formation
DBS0237035vasP-vasPdecreased cell-substrate adhesion | aberrant F-actin organization | decreased chemotaxis rate | decreased lateral pseudopod suppression | decreased cell size | abolished filopodium formation | decreased filopodium formation
DBS0237033vasP-/ [act15]: GFP: vasP(1-264/ 285-380)vasPabolished filopodium formation
DBS0237836vasP-/ [act15]: YFP: wipAvasP | wipAdecreased filopodium formation
DBS0237842vasP-/ [act15]: YFP: wipA/ [act15]: vasP: FLAGvasP | wipAincreased filopodium formation
DBS0237036vasP-/ [act15]: myr: vasPvasPincreased filopodium formation | increased basal F-actin level | aberrant cytokinesis
DBS0237040vasP-/ [act15]: vasPvasPdecreased filopodium formation
DBS0237840vasP-/ [act15]: vasPvasPincreased filopodium formation | increased basal F-actin level
DBS0237037vasP-/ [act15]: vasP(1-110: 231-380)vasPincreased basal F-actin level | aberrant cytokinesis | decreased filopodium formation
DBS0237038vasP-/ [act15]: vasP(1-228)vasPdecreased filopodium formation
DBS0237039vasP-/ [act15]: vasP(111-380)vasPincreased filopodium formation | increased basal F-actin level
DBS0236058vmp1-vmp1aberrant aggregation | decreased exocytosis | decreased pinocytosis | aberrant response to hypo-osmotic stress | decreased gene expression | decreased growth rate
DG1118vps46-vps46increased sorus size
DBS0237046vwkA-vwkAdecreased growth rate in suspension | increased myosin II assembly | aberrant cytokinesis | delayed development | increased protein level | aberrant fruiting body morphology
TL61wacA-wacAwild type
TL99wacA-wacAwild type
DBS0237048warA-warAdevelopment arrests at slug stage | increased basal disc size | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0237049warA-warAdevelopment arrests at slug stage | increased basal disc size | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0237050warA-/ hbx2-hbx2 | warAincreased basal disc size | development arrests at mound stage | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0237051wasA1-wasAaberrant F-actin organization | decreased cell motility | delayed development
DBS0237052wasA1-/ [tet]: YFP: wasA2wasAdecreased F-actin polymerization | abolished chemotaxis | aberrant F-actin organization | abolished aggregation
DBS0237812wasA1-/ [tet]: YFP: wasA2/ [act15]: wasAwasAincreased F-actin polymerization at the leading edge
DBS0237811wasA1-/ [tet]: YFP: wasA2/ [act15]: wasA(Y33A/ W39A/ F90A/ F91A)wasAdecreased F-actin polymerization | decreased F-actin polymerization at the leading edge
DBS0237820wasA1-/ [tet]: YFP: wasA2/ [act15]: wipAwasA | wipAabolished chemotaxis
DG1053wimA-wimAaberrant fruiting body morphology
DG1064wimA-wimAaberrant fruiting body morphology
HM1458xpc-xpcwild type
HM1403xpf-xpfincreased sensitivity to cisplatin | decreased double-strand break repair via homologous recombination
AK235yakA-yakAabolished aggregation
AK800yakA-yakAabolished aggregation
DBS0237091yakA-/ [crlA]: crlAcrlA | yakAabolished growth
AK804yakA-/ pufA-pufA | yakAincreased growth rate
DG1014yelA-yelAdecreased spore viability | precocious sporulation | development arrests at mound stage | aberrant mound color
DBS0349797zak2-zak2decreased gene expression | decreased protein kinase activation | decreased sporulation | aberrant fruiting body morphology
DBS0349798zak2-/ [ecmA]: LacZzak2aberrant gene expression
ARK100-110zakA-zakAdecreased glycogen synthase kinase 3 activity | increased gene expression | decreased gene expression | abolished streaming | decreased chemotaxis to cAMP | delayed culmination | aberrant fruiting body morphology | decreased sporulation
DBS0238142zakA-zakAdevelopment arrests at tipped mound stage
DBS0349803zakA-/ [ecmB]: LacZzakAaberrant gene expression
DG1050zipA-zipAdecreased fruiting body size

Last updated January 28, 2012

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