Dictyostelium Mutants

Phenotypes for Dictyostelium mutants

View other mutant types: All mutant strains - Null - Overexpression - Multiple - Other - Developmental

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Systematic Name Strain Descriptor Associated gene(s) Phenotypes
DBS02354121C7gp130decreased cell-substrate adhesion | delayed development | increased growth rate
DBS02354142F5gp130decreased cell-substrate adhesion | delayed development | increased growth rate
DBS02386015NT-5NTmultiple tips in culminant | delayed tip formation | multiple tips in mound
DBS0235584CF45-1-cf45-1increased aggregate size | decreased cell motility | increased cell-cell adhesion | decreased aggregate size | increased intracellular glucose level
DBS0235585CF50-cf50-1increased aggregate size | increased gene expression | increased cell-cell adhesion | decreased extracellular counting factor component(s) level | increased protein level
DBS0235594CHE10cbpCdecreased slug migration | precocious aggregation | decreased aggregate size | decreased fruiting body size | delayed culmination
DBS0235595CHI2cbpCincreased slug migration
DBS0235612CMFR1-cmfBdecreased gene expression | abolished aggregation
DBS0235659DD3-3-DD3-3decreased gene expression | precocious aggregation
DG1007DDB_G0269232-DDB_G0269232abolished culmination
DG1003DDB_G0291992-DDB_G0291992aberrant culminant morphology
DG1039DG1039-DDB_G0284037aberrant fruiting body morphology
DG1040DG1040-DDB_G0276029aberrant fruiting body morphology
DG1041DG1041-DDB_G0269126aberrant fruiting body morphology
DG1054DG1054-DDB_G0277719aberrant fruiting body morphology
DG1060DG1060-DDB_G0281953aberrant fruiting body morphology
DG1062DG1062-DDB_G0286351aberrant fruiting body morphology
DG1074DG1074-DDB_G0272108aberrant fruiting body morphology
DG1080DG1080-DDB_G0281559aberrant fruiting body morphology
DG1091DG1091-DG1091decreased fruiting body size
DG1098DG1098-DG1098decreased fruiting body size
DG1104DG1104-DDB_G0283535abolished aggregation
DG1105DG1105-DG1105abolished aggregation
DG1106DG1106-DG1106abolished aggregation
DG1110DG1110-DDB_G0269128aberrant fruiting body morphology
DG1112DG1112-DG1112decreased stalk width
DG1113DG1113-DG1113increased stalk length
DG1122DG1122-DG1122aberrant fruiting body morphology
DG1124DG1124-DG1124development arrests at loose aggregate stage
DG2033DG2033-DG2033development arrests at mound stage
DG2044DG2044-DG2044development arrests at loose aggregate stage
DBS0266692Dd5P4-Dd5P4decreased growth rate | decreased phagocytosis | decreased engulfment during phagocytosis | multiple tips in mound
DBS0266695Dd5P4-/ [act15]: GAP5P4Dd5P4decreased growth rate | multiple tips in mound
DBS0266694Dd5P4-/ [act15]: cat5P4Dd5P4decreased growth rate | multiple tips in mound
CW0391FLAG-VwkAvwkAdecreased growth rate in suspension | increased myosin II assembly | aberrant cytokinesis | development arrests at mound stage | increased protein level
DBS0236015GEG04K11 (tmcB- in KAX3)tmcBsmall macrocysts | increased number of peripheral cells during sexual reproduction | aberrant aggregation during macrocyst formation
DBS0236016GEG04V12 (tmcB- in V12)tmcBsmall macrocysts | increased number of peripheral cells during sexual reproduction | aberrant aggregation during macrocyst formation
DBS0236017GEG10K23 (tmcC- in KAX3)tmcCincreased number of peripheral cells during sexual reproduction | aberrant aggregation during macrocyst formation
DBS0236018GEG10V03 (tmcC- in V12)tmcCincreased number of peripheral cells during sexual reproduction | aberrant aggregation during macrocyst formation
DBS0236358HR42fbxAabolished culmination | decreased sporulation
HTY506HTY506pkaRaberrant spore morphology | decreased spore viability | decreased phosphorylation of actin | increased sporulation | precocious development | aberrant fruiting body morphology
DBS0236444JH.DcbfAabolished gene expression | decreased gene expression | decreased growth rate | increased pinocytosis | increased cell size | decreased fruiting body size | decreased stalk width | abolished aggregation | increased phagocytosis
DBS0236779PIPkinA-pik6decreased gene expression | abolished aggregation
DBS0236783PKAcat-pkaCabolished aggregation
DBS0236840R7nosAdevelopment arrests at mound stage
DBS0236900RIP3ripAdecreased cell polarity | abolished activation of adenylate cyclase | decreased chemotaxis rate | abolished aggregation | decreased myosin II assembly
DBS0236982TL114csbAdecreased cell-cell adhesion | abolished aggregation
DBS0236996TL26cotBaberrant spore coat morphology
DBS0264065V00262dagAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264066V00347DDB_G0281917abolished culmination
DBS0264073V10108DDB_G0292162abolished slug migration | aberrant vegetative growth | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264075V10113yakAabolished slug migration | aberrant vegetative growth | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation | aberrant cAMP wave formation
DBS0264078V10116tipBaberrant aggregation | abolished slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264079V10117DDB_G0285083aberrant slug migration | abolished culmination
DBS0264087V10125DDB_G0293302aberrant slug migration | aberrant cAMP wave formation
DBS0264088V10126tipCaberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264089V10127DG1037abolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation | aberrant cAMP wave formation
DBS0264098V10136DDB_G0293590wild type | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264099V10137yelAaberrant aggregation | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0264106V10144comHaberrant aggregation | abolished slug migration | abolished culmination
DBS0264108V10146yakAabolished slug migration | aberrant vegetative growth | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264109V10147tipAaberrant streaming | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264116V10155DDB_G0282093aberrant streaming | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant slug migration | abolished streaming | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264118V10157usp12aberrant streaming | aberrant culmination | aberrant slug migration | abolished culmination
DBS0264125V10164comEaberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished culmination
DBS0264126V10165comDaberrant aggregation | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0264128V10167DG1098wild type | aberrant cAMP wave formation
DBS0264129V10168prsCwild type | aberrant slug migration
DBS0264131V10170DDB_G0283015aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264135V10174DDB_G0288581aberrant streaming | aberrant vegetative growth | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264145V10185abcA5wild type | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0264150V10190yelAaberrant aggregation | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0264151V10191sfbAaberrant culmination | aberrant slug migration | abolished culmination
DBS0264152V10192tipDaberrant aggregation | abolished slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264154V10194modAaberrant culmination | aberrant slug migration
DBS0264155V10195migAaberrant streaming | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264157V10197yelAabolished slug migration | aberrant culmination | aberrant slug migration
DBS0264158V10198splAaberrant streaming | aberrant aggregation | aberrant culmination | aberrant cAMP wave formation
DBS0264159V10199DG1037aberrant streaming | abolished slug migration | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264160V10200DDB_G0289377aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264161V10201rgaAaberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264163V10203modAwild type | aberrant vegetative growth | aberrant culmination
DBS0264164V10204DG1124aberrant streaming | aberrant aggregation | aberrant cAMP wave formation
DBS0264169V10209dcsAabolished culmination
DBS0264170V10210mkpAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264171V10211migAaberrant streaming | aberrant culmination | aberrant cAMP wave formation
DBS0264172V10212tipCaberrant aggregation | abolished slug migration | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0264173V10213DG1098aberrant streaming | aberrant cAMP wave formation
DBS0264181V10221tipDaberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264183V10223erkAaberrant streaming | aberrant cAMP wave formation
DBS0264184V10224DG1091aberrant cAMP wave formation
DBS0264185V10225acrAaberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264186V10226ggtAaberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished aggregation | abolished culmination
DBS0264187V10227piaAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264188V10228comGaberrant aggregation | aberrant streaming | abolished slug migration | aberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264189V10229dcsAabolished culmination | aberrant cAMP wave formation
DBS0264190V10230ctrAaberrant aggregation | aberrant culmination | aberrant slug migration
DBS0264193V10233piaAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264196V10236DDB_G0270872_psaberrant streaming
DBS0264198V10238DDB_G0269128aberrant culmination | aberrant slug migration
DBS0264199V10239kif12wild type | aberrant culmination
DBS0264201V10241lvsBaberrant culmination
DBS0264202V10242tagBaberrant aggregation | abolished slug migration | abolished culmination
DBS0264204V10244gbfAaberrant culmination | aberrant slug migration
DBS0264205V10245gefAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264206V10246dicBaberrant streaming | aberrant cAMP wave formation
DBS0264207V10247yelAaberrant aggregation | abolished slug migration | aberrant culmination | abolished culmination | aberrant cAMP wave formation
DBS0264212V10252tagBaberrant aggregation | abolished slug migration | abolished culmination
DBS0264216V10256DDB_G0293302aberrant streaming | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0264218V10258rdeAaberrant streaming | aberrant aggregation | abolished slug migration | aberrant culmination | abolished culmination | aberrant cAMP wave formation
DBS0264220V10260gacTaberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264224V10264DDB_G0282787_RTEaberrant streaming | aberrant aggregation | wild type | abolished slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264225V10265lvsDaberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0264227V10267DDB_G0292260_RTEaberrant streaming | aberrant aggregation
DBS0264228V10268dhkAaberrant streaming | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264229V10269helCwild type | aberrant culmination | aberrant slug migration | abolished culmination
DBS0264230V10270mekAaberrant streaming | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0264231V10271lvsBabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264232V10272modAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264234V10274DG1113aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0264235V10275DG1122aberrant streaming | wild type | abolished slug migration | aberrant vegetative growth | abolished streaming | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264237V10277lvsEaberrant cAMP wave formation
DBS0264238V10278modAaberrant streaming | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264240V10280mekAaberrant streaming | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264241V10281DDB_G0268266aberrant slug migration | aberrant cAMP wave formation
DBS0264242V10282phdAaberrant streaming | abolished slug migration | aberrant culmination
DBS0264245V10285DG1105abolished slug migration | aberrant vegetative growth | abolished streaming | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0264246V10286amdAwild type | aberrant culmination
DBS0264247V10287helCwild type | aberrant culmination | aberrant slug migration
DBS0264251V10300DDB_G0278333aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264268V10321adprt1Bwild type | aberrant cAMP wave formation
DBS0264269V10322roco5aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264272V10326DG1113wild type | aberrant cAMP wave formation
DBS0264281V10356DDB_G0275747aberrant slug migration
DBS0264284V10367DDB_G0282463aberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264287V10431kcnma1wild type | aberrant culmination | aberrant slug migration
DBS0264290V10435gefLabolished slug migration | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264297V10445DDB_G0290835aberrant slug migration
DBS0264303V10460abcC9aberrant slug migration
DBS0264316V10483yod1aberrant aggregation | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264318V10490gefVaberrant culmination | aberrant cAMP wave formation
DBS0264319V10492med23aberrant culmination | aberrant cAMP wave formation
DBS0264320V10495DDB_G0269128wild type | aberrant culmination | aberrant slug migration
DBS0264324V10514adprt3aberrant streaming | aberrant cAMP wave formation
DBS0264330V10529cyp508B1aberrant streaming | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264331V10530DDB_G0270344wild type | aberrant slug migration | aberrant cAMP wave formation
DBS0264334V10534DDB_G0291812wild type | aberrant culmination
DBS0264335V10535DDB_G0277165aberrant streaming | aberrant cAMP wave formation
DBS0264337V10537gbpCaberrant streaming | wild type | abolished streaming | aberrant cAMP wave formation
DBS0264347V10567dagAabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264349V10570DDB_G0281115aberrant streaming | wild type | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264356V10588dhkCaberrant streaming | wild type | aberrant cAMP wave formation
DBS0264373V10633gtaGabolished slug migration | aberrant culmination | aberrant slug migration | abolished culmination
DBS0264390V10682clcDabolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation | aberrant cAMP wave formation
DBS0264425V11033nfaAaberrant streaming | aberrant aggregation | wild type | aberrant cAMP wave formation
DBS0264432V11040DDB_G0274177abolished slug migration | abolished streaming | abolished aggregation | abolished culmination | abolished cAMP wave formation
DBS0264446V11055ku80aberrant vegetative growth | aberrant culmination
DBS0264464V11075cinCwild type | aberrant culmination
DBS0264489V11105DDB_G0270350_psaberrant streaming | wild type | aberrant cAMP wave formation
DBS0264512V11128DDB_G0278945aberrant streaming | aberrant vegetative growth | aberrant cAMP wave formation
DBS0264575V30069DDB_G0284619aberrant streaming | aberrant cAMP wave formation
DBS0264607V30110alg9wild type | aberrant vegetative growth | aberrant cAMP wave formation
DBS0264630V30133DDB_G0272953aberrant streaming | wild type | aberrant cAMP wave formation
DBS0264662V30165alg9aberrant streaming | wild type | aberrant culmination | aberrant cAMP wave formation
DBS0264668V30171DDB_G0285261aberrant streaming | wild type | aberrant vegetative growth | aberrant cAMP wave formation
DBS0264677V30180gpaFaberrant streaming | wild type | aberrant cAMP wave formation
DBS0264684V30188DDB_G0287723aberrant streaming | wild type | aberrant cAMP wave formation
DBS0264700V30213act9wild type | aberrant culmination
DBS0264715V30229dhx35wild type | aberrant cAMP wave formation
DBS0264716V30230regAaberrant streaming | aberrant aggregation | abolished slug migration | abolished culmination | aberrant cAMP wave formation
DBS0264731V30245DDB_G0279461wild type | aberrant culmination
DBS0264773V30288DDB_G0293300aberrant streaming | wild type | aberrant cAMP wave formation
DBS0264785V30303pakEaberrant cAMP wave formation
DBS0264823V30341frmBaberrant streaming | wild type | aberrant culmination
DBS0264853V30371abpCaberrant aggregation | abolished slug migration | aberrant culmination | abolished culmination
DBS0264905V30427DDB_G0291926aberrant streaming | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0264924V30448DDB_G0269680wild type | aberrant cAMP wave formation
DBS0264941V30466dtfAwild type | aberrant cAMP wave formation
DBS0264992V30522DDB_G0288007aberrant streaming | wild type | aberrant cAMP wave formation
DBS0264994V30524prmt5aberrant streaming | aberrant culmination | aberrant slug migration | abolished culmination | aberrant cAMP wave formation
DBS0265002V30532lvsAwild type | abolished slug migration | abolished aggregation | abolished culmination | aberrant cAMP wave formation
DBS0265017V30547DDB_G0279105aberrant streaming | wild type | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0265029V30561DDB_G0277355wild type | aberrant culmination
DBS0265045V30578DDB_G0277165aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0265064V30604DDB_G0279461aberrant streaming | abolished slug migration | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0265099V30642tipCaberrant aggregation | abolished slug migration | abolished culmination | aberrant cAMP wave formation
DBS0265126V30673dicBaberrant aggregation | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0265140V30688DDB_G0279727wild type | aberrant culmination
DBS0265303V30870gxcJJwild type | aberrant cAMP wave formation
DBS0265309V30876DDB_G0268248aberrant streaming | wild type | aberrant cAMP wave formation
DBS0265311V30879exoc2aberrant streaming | wild type | aberrant cAMP wave formation
DBS0265339V30912DDB_G0283821wild type | aberrant cAMP wave formation
DBS0265348V30921snpCwild type | aberrant culmination
DBS0265466V31043DDB_G0275917aberrant aggregation | wild type | aberrant vegetative growth | aberrant slug migration | abolished culmination
DBS0265497V31075DDB_G0282985aberrant streaming | wild type | abolished slug migration | aberrant culmination | abolished aggregation | aberrant cAMP wave formation
DBS0265529V31111vps13Eaberrant streaming | wild type | aberrant culmination | aberrant cAMP wave formation
DBS0265539V31121DDB_G0270912wild type | aberrant vegetative growth | aberrant cAMP wave formation
DBS0265567V31151DDB_G0275539wild type | aberrant vegetative growth | abolished culmination
DBS0265588V31173ggtAaberrant streaming | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0265662V31255psiNaberrant streaming | wild type | aberrant culmination | aberrant cAMP wave formation
DBS0265688V31281DDB_G0286417aberrant streaming | wild type | aberrant culmination | aberrant cAMP wave formation
DBS0265873V31480DDB_G0284177aberrant culmination
DBS0265890V31501DDB_G0282985wild type | aberrant culmination | aberrant cAMP wave formation
DBS0265908V31523tmem184Cwild type | aberrant culmination
DBS0265911V31528DDB_G0279945aberrant culmination
DBS0265938V31568rsc12aberrant culmination
DBS0266000V31649DDB_G0290383wild type | aberrant culmination
DBS0266022V31671dhkAaberrant culmination | aberrant slug migration
DBS0266036V31685tipCaberrant streaming | aberrant aggregation | wild type | abolished slug migration | aberrant culmination | aberrant cAMP wave formation
DBS0266084V31738dcsAwild type | aberrant culmination | abolished culmination
DBS0266088V31742dstAaberrant culmination | aberrant slug migration | abolished culmination
DBS0266089V31743DDB_G0273459aberrant streaming | aberrant aggregation | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0266098V31752oplahwild type | aberrant cAMP wave formation
DBS0266153V31811gpt1wild type | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0266190V31853chlAaberrant aggregation | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0266195V31858DDB_G0286341aberrant streaming | wild type | aberrant cAMP wave formation
DBS0266246V31916psiFwild type | aberrant vegetative growth | aberrant culmination | aberrant cAMP wave formation
DBS0266249V31919DDB_G0276251aberrant streaming | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0266253V31923DDB_G0268314wild type | aberrant culmination
DBS0266271V31941manAaberrant streaming | aberrant aggregation | aberrant culmination | aberrant slug migration | aberrant cAMP wave formation
DBS0266299V31970DDB_G0280581aberrant streaming | wild type | aberrant cAMP wave formation
DBS0266309V31982DDB_G0286341aberrant streaming | wild type | abolished streaming | aberrant cAMP wave formation
DBS0266316V31989DDB_G0270342wild type | abolished slug migration | aberrant culmination | abolished streaming | aberrant cAMP wave formation
DBS0237236[AS]: [tet]: trrAtrrAdecreased growth rate | delayed development | abolished aggregation
DBS0237228[AS]GP138A/ [AS]GP138BcfrAdecreased sexual fusion
DBS0237228[AS]GP138A/ [AS]GP138BcfrBdecreased sexual fusion
DBS0237222[AS]cf60cf60increased aggregate size | decreased number of aggregates
DBS0237223[AS]chcAchcAdecreased pinocytosis | delayed response to hypo-osmotic stress | decreased number of vacuoles | aberrant vacuole organization and biogenesis | abolished aggregation | decreased cell size
DBS0237224[AS]cmfAcmfAabolished aggregation
DBS0237225[AS]cupBcupBabolished aggregation
DBS0237226[AS]dia1dia1decreased gene expression | precocious aggregation
HPF414[AS]hspAhspAdecreased growth rate | aberrant fruiting body morphology
DBS0304425[AS]mppA1mppA1delayed development
DBS0237504[AS]pikEpikEaberrant stalk morphogenesis | decreased growth rate
DBS0237231[AS]ppiAppiAincreased stalk length
DBS0236827[AS]proA/ proB-proAincreased basal F-actin level | abolished growth | development arrests at slug stage | aberrant cytokinesis | decreased cell motility
DBS0236827[AS]proA/ proB-proBincreased basal F-actin level | abolished growth | development arrests at slug stage | aberrant cytokinesis | decreased cell motility
DBS0236904[AS]rps4mrps4delayed aggregation | aberrant fruiting body morphology
DBS0237234[AS]smlAsmlAdecreased fruiting body size
DBS0238748[AS]snfAsnfAdecreased number of mitochondria | aberrant mitochondrion organization and biogenesis | decreased intracellular ATP level | increased growth rate | decreased fruiting body size
DBS0304498[AS]sslA1sslA1decreased fruiting body size
DBS0237235[AS]tcp1tcp1decreased growth rate | development arrests at mound stage | aberrant fruiting body morphology
DBS0306102[AS]vatPvatPdecreased extracellular Ca2+ uptake | decreased growth rate | delayed development
DBS0266892[KD]gtaCgtaCabolished stalk cell differentiation
DBS0237276[OE]: GFP: gxcAgxcAabolished aggregation
DBS0237277[OE]: gpaDgpaDaberrant fruiting body morphology | decreased sporulation
JH258[OE]: gpaEgpaEprecocious tip formation | precocious gene expression
DBS0302682[OE]: sgcA(N1106A): GFP/ gca-/ sgcA-gcAaberrant streaming | increased lateral pseudopod formation | decreased chemotaxis rate
DBS0302682[OE]: sgcA(N1106A): GFP/ gca-/ sgcA-sgcAaberrant streaming | increased lateral pseudopod formation | decreased chemotaxis rate
DBS0237284[OE]GFP: gxcA(1-750: 764-1217)gxcAdevelopment arrests at loose aggregate stage
DBS0237285[OE]GFP: gxcA(1-750: 764-984)gxcAdevelopment arrests at loose aggregate stage
DBS0235409[RNAi]cnbAcnbAmultiple tips in culminant | decreased gene expression | aberrant stalk cell differentiation | decreased stalk length
DBS0349787[RNAi]ctnnActnnAaberrant protein secretion | aberrant tip formation | aberrant Golgi localization | abolished stalk formation | aberrant centrosome localization | abolished culmination | abolished cell polarity | aberrant protein localization
DBS0237308[RNAi]gmsAgmsAdecreased sexual fusion
DBS0237309[RNAi]gsrgsrprecocious culmination | decreased sorting to prestalk region | precocious gene expression
DBS0238734[RNAi]sdhAsdhAabolished aggregation | decreased phototaxis
DBS0237313[RNAi]tmcBtmcBaberrant macrocyst differentiation
DBS0237314[RNAi]tmcCtmcCaberrant macrocyst differentiation
DBS0237315[RNAi]trap1trap1decreased gene expression | delayed development
DBS0238108[act15]: FLAG: ppp4C(H113Q)ppp4cdevelopment arrests at mound stage | delayed development
DBS0237117[act15]: GFP: krsAkrsAdecreased slug migration
DBS0238111[act15]: HA: smkAsmkAdecreased cell polarity | delayed development | decreased fruiting body size | decreased chemotaxis to cAMP
DBS0237227[act15]: [AS]dia2dia2decreased extracellular cAMP level | aberrant cAMP signaling during aggregation | abolished aggregation
DBS0237096[act15]: abpEabpE-1aberrant aggregation | increased lateral pseudopod formation | decreased cell motility | delayed development | decreased fruiting body size
DBS0237096[act15]: abpEabpE-2aberrant aggregation | increased lateral pseudopod formation | decreased cell motility | delayed development | decreased fruiting body size
DBS0238088[act15]: atg1(K36A)atg1abolished macroautophagy | increased number of autophagosomes | aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0252740[act15]: carA(I104D)carA-1increased cAMP binding | delayed aggregation | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0252740[act15]: carA(I104D)carA-2increased cAMP binding | delayed aggregation | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0252744[act15]: carA(I104E)carA-1increased cAMP binding | delayed aggregation | aberrant cAMP wave formation
DBS0252744[act15]: carA(I104E)carA-2increased cAMP binding | delayed aggregation | aberrant cAMP wave formation
DBS0252747[act15]: carA(I104H)carA-1development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252747[act15]: carA(I104H)carA-2development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252749[act15]: carA(I104K)carA-1increased cAMP binding | decreased MAP kinase activation | abolished aggregation | abolished cAMP wave formation
DBS0252749[act15]: carA(I104K)carA-2increased cAMP binding | decreased MAP kinase activation | abolished aggregation | abolished cAMP wave formation
DBS0252746[act15]: carA(I104N)carA-1development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252746[act15]: carA(I104N)carA-2development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252745[act15]: carA(I104Q)carA-1development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252745[act15]: carA(I104Q)carA-2development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252750[act15]: carA(I104R)carA-1development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252750[act15]: carA(I104R)carA-2development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252743[act15]: carA(I104S)carA-1increased cAMP binding | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0252743[act15]: carA(I104S)carA-2increased cAMP binding | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0252735[act15]: carA(I104T)carA-1increased cAMP binding | aberrant cAMP wave formation
DBS0252735[act15]: carA(I104T)carA-2increased cAMP binding | aberrant cAMP wave formation
DBS0252748[act15]: carA(I104Y)carA-1development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0252748[act15]: carA(I104Y)carA-2development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0237098[act15]: cdk5(D144N)cdk5decreased pinocytosis | increased aggregate size | delayed aggregation | decreased phagocytosis | decreased growth rate | decreased extracellular counting factor component(s) level | increased extracellular counting factor component(s) level | decreased sporulation | increased intracellular counting factor component(s) level
DBS0237099[act15]: cf60cf60aberrant regulation of aggregate size | increased number of aggregates
DBS0302445[act15]: cfaDcfaDdecreased growth rate | aberrant fruiting body morphology
DBS0302658[act15]: cnrN/ smlA-cnrNdecreased fruiting body size
DBS0302658[act15]: cnrN/ smlA-smlAdecreased fruiting body size
DBS0237105[act15]: dgkAdgkAdevelopment arrests at loose aggregate stage | decreased chemotaxis rate | decreased myosin II assembly
DBS0237106[act15]: dhkC(394-661)dhkCincreased slug migration
DBS0235716[act15]: dhkKdhkKprecocious aggregation | development arrests at mound stage
DBS0235705[act15]: dhkK(D1125N)dhkKaberrant cAMP signaling during aggregation | delayed development
DBS0235707[act15]: dhkK(H825Q)dhkKprecocious development | decreased fruiting body size
DBS0235709[act15]: dhkK(H825Q/ D1125N)dhkKaberrant slug migration | delayed culmination
DBS0237107[act15]: dng1dng1decreased growth rate | precocious aggregation | aberrant cAMP signaling during aggregation
DBS0237108[act15]: fbxA: FLAGfbxAdecreased prespore cell differentiation
DBS0237136[act15]: gpaAgpaAincreased stalk length | aberrant cytokinesis | aberrant fruiting body morphology
DBS0237145[act15]: gpaGgpaGaberrant fruiting body morphology
DBS0237147[act15]: gpaI(G38V): FLAGgpaIincreased aggregate size | delayed aggregation | decreased number of aggregates | aberrant fruiting body morphology
DBS0237148[act15]: gpaI(Q196L): FLAGgpaIincreased aggregate size | delayed aggregation | decreased number of aggregates | aberrant fruiting body morphology
DBS0237149[act15]: grxAgrxAdecreased gene expression | delayed culmination
DBS0237152[act15]: grxA/ [act15]: lacZgrxAincreased sorting to prestalk region
DBS0237153[act15]: gsrgsrincreased sorting to prestalk region | delayed culmination
DBS0237157[act15]: mkkAmkkAdevelopment arrests at mound stage | delayed development
DBS0237158[act15]: mkkA(K199A)mkkAprecocious development | decreased sporulation
DBS0237159[act15]: mkkA{deltaWD40}mkkAdevelopment arrests at mound stage | delayed development | aberrant fruiting body morphology
DBS0237162[act15]: myc-cdk8cdk8multiple tips
DBS0266837[act15]: myc: ptpCptpCaberrant signal transduction during aggregation | aberrant response to hyperosmotic stress | aberrant protein localization
DBS0238396[act15]: myc: rapA(G12V)rapAdelayed aggregation | increased cell-substrate adhesion | decreased cell motility
DBS0237167[act15]: myc: rckArckAdelayed development
DBS0237163[act15]: myc: rckA(C551A)rckAdelayed slug formation | decreased chemotaxis rate
DBS0237164[act15]: myc: rckA(E510G)rckAdelayed slug formation | decreased chemotaxis rate
DBS0237165[act15]: myc: rckA(E510G/ N511A)rckAdelayed slug formation | decreased chemotaxis rate
DBS0237166[act15]: myc: rckA(K867A)rckAdelayed slug formation | precocious aggregation | decreased chemotaxis rate
DBS0237175[act15]: myoMmyoMaberrant streaming | delayed development | increased pseudopod size
DBS0237178[act15]: myoM-MtailmyoMaberrant streaming | aberrant response to hyperosmotic stress | aberrant response to hypo-osmotic stress | decreased growth rate | delayed development | increased pseudopod size
DBS0237179[act15]: myr: rckArckAdelayed development | decreased chemotaxis rate
DBS0237183[act15]: pakA(K394A)pakAdevelopment arrests at mound stage | delayed development
DBS0237184[act15]: pakA[CA]pakAabolished aggregation
DBS0237188[act15]: pkaR(1-497)pkaRprecocious development | decreased intracellular cAMP level | decreased fruiting body size
DBS0235442[act15]: pldB: GFPpldBabolished aggregation
DBS0238735[act15]: snfA(1-379): GFPsnfAincreased stalk width | increased intracellular ATP level | decreased growth rate | increased number of mitochondria | aberrant mitochondrion organization and biogenesis | decreased phototaxis | decreased stalk length
DBS0237194[act15]: sodA: mycsodAdecreased gene expression | abolished aggregation
DBS0237195[act15]: spkA: FLAGspkA-1aberrant aggregation | decreased cell polarity | aberrant F-actin organization | decreased chemotaxis rate
DBS0237195[act15]: spkA: FLAGspkA-2aberrant aggregation | decreased cell polarity | aberrant F-actin organization | decreased chemotaxis rate
AK1209[act15]: tagA(1-890)tagAmultiple tips in mound
DBS0237199[act15]: trrAtrrAaberrant aggregation | decreased growth rate | decreased phagocytosis | delayed culmination
DBS0237205[act6]: dia1dia1delayed aggregation
DBS0236905[act6]: mrps4mrps4precocious aggregation
DBS0235444[act6]: myc: eppA(S250A)eppAdecreased growth rate | delayed development | decreased intracellular cAMP level
DBS0266836[act6]: ptpBptpBdelayed aggregation | decreased fruiting body size
DBS0237218[act6]: ptpCptpCincreased aggregate size | decreased growth rate
DBS0237219[act6]: ptpC(C649S)ptpCincreased aggregate size | decreased growth rate
DBS0304410[act6]: srsAsrsAincreased aggregate size | decreased gene expression | increased slug size | delayed aggregation | decreased sporulation | aberrant fruiting body morphology
DBS0237220[act6]: trap1trap1development arrests at loose aggregate stage | aberrant aggregation | abolished pinocytosis | increased gene expression | decreased gene expression | decreased growth rate
DBS0237221[arkA]: arkA: myc2arkAaberrant aggregation
DBS0237239[dscB]: GFP: rab8A(N128I)rab8Aincreased aggregate size | increased cell-cell adhesion | decreased fruiting body size
DBS0237240[dscB]: GFP: rab8A(Q74L)rab8Aaberrant cytoskeleton organisation | abolished aggregation
DBS0237241[dscB]: GFP: rab8Brab8Bincreased aggregate size
DBS0237242[dscB]: GFP: rab8B(Q74L)rab8Bincreased aggregate size
DBS0237243[dscB]: myc: rac1Brac1Bdecreased growth rate in suspension | increased rate of endocytosis | aberrant cytokinesis | delayed development
DBS0237244[dscB]: myc: rac1B(G12V)rac1Bdecreased rate of endocytosis | decreased growth rate in suspension | abolished aggregation | aberrant cell morphology
DBS0237245[dscB]: myc: rac1B(Q61L)rac1Bdecreased rate of endocytosis | decreased growth rate in suspension | abolished aggregation | aberrant cell morphology
DBS0237246[dscB]: myc: rac1B(T17N)rac1Bdecreased rate of endocytosis | decreased growth rate in suspension | abolished aggregation
DBS0304865[expl7]: expl7: GFPexpl7aberrant culminant morphology
DBS0237252[gpaA]: gpaA(G45V)gpaAdelayed development
DBS0237253[gpaA]: gpaA(Q206L)gpaAincreased basal disc size
DBS0236484[pkaC]: pkaCpkaCdecreased intracellular cAMP level | precocious development | aberrant fruiting body morphology
DBS0237289[psmC1]: psmC1psmC1aberrant cytokinesis | delayed tip formation | delayed gene expression
DBS0237290[ptpA1]ptpA1ptpA1-1delayed aggregation | decreased growth rate | aberrant fruiting body morphology
DBS0237291[ptpB]ptpBptpBdecreased growth rate | development arrests at mound stage
DBS0238351[tet]: [RNAi]cinCcinCdecreased translation | precocious aggregation | decreased growth rate
DBS0304911[tre]: paxBpaxBabolished sporulation | aberrant endocytosis | decreased cell-substrate adhesion | aberrant chemotaxis to folate | development arrests at mound stage | decreased cell motility | increased cell-cell adhesion
DBS0304636[unk]: rasG(Q61L)/ rasG-rasGaberrant cAMP signaling during aggregation
DBS0237288[unk]skp1fpaAaberrant fruiting body morphology
DBS0237288[unk]skp1fpaB-1aberrant fruiting body morphology
HAD186aarA-aarAaberrant tip formation | aberrant establishment and/ or maintenance of cell polarity | aberrant stalk formation | aberrant Golgi localization | aberrant centrosome localization | decreased sporulation | aberrant fruiting body morphology
DBS0235425abpB-/ fimA-abpBdecreased fruiting body size | decreased sporulation | decreased cell size
DBS0235425abpB-/ fimA-fimAdecreased fruiting body size | decreased sporulation | decreased cell size
DBS0235427abpD-abpDdecreased cell-cell adhesion | decreased spore viability | delayed development | aberrant development
DBS0235562acaA-acaAabolished aggregation | decreased adenylate cyclase activity | abolished cell polarity | abolished streaming
DBS0306126acapA-/ acapB-acapAdecreased sporulation
DBS0306126acapA-/ acapB-acapBdecreased sporulation
TL177acbA-acbAincreased sensitivity to cisplatin | abolished SDF production | decreased spore viability | abolished sorting to prestalk region
AK1211acbA-/ tagA-acbAincreased prestalk B cell differentiation
AK1211acbA-/ tagA-tagAincreased prestalk B cell differentiation
DBS0235440acgA-acgAprecocious spore germination
DBS0237788acgA-acgAdecreased gene expression | decreased prespore cell differentiation
DG1100acrA-acrAdecreased gene expression | increased stalk length | spores inviable | decreased sporulation
DBS0237786acrA-/ [act15]: acgA(1-401)acgAdecreased gene expression | decreased prespore cell differentiation | decreased sporulation
DBS0237786acrA-/ [act15]: acgA(1-401)acrAdecreased gene expression | decreased prespore cell differentiation | decreased sporulation
DBS0238203adrm1-adrm1-1aberrant response to nutrients | precocious gene expression | precocious development
DBS0235457ahhA-ahhAaberrant culminant morphology
DBS0235513alrA-alrAincreased aggregate size | decreased intracellular glucose level | decreased cell motility | decreased extracellular counting factor component(s) level
DBS0235474alxA-alxAdevelopment arrests at loose aggregate stage | decreased growth rate | aberrant fruiting body morphology
DBS0235475alxA-alxAabolished sporulation | decreased gene expression | development arrests at mound stage | aberrant fruiting body morphology
DBS0235488alxA-/ [act15]: FLAG: alxAalxAdelayed development
DBS0235478alxA-/ [act15]: alxA(155-697): myc2alxAaberrant fruiting body morphology
DBS0235479alxA-/ [act15]: alxA(293-697): myc2alxAaberrant fruiting body morphology
DBS0235480alxA-/ [act15]: alxA(460-794): myc2alxAaberrant fruiting body morphology
DG1114amdA-amdAdecreased spore viability | translucent sorus | increased prestalk A cell differentiation
HM1158amdA-amdAdecreased fruiting body size | decreased sporulation | increased aspidocyte differentiation
DBS0235490amiB-amiBabolished aggregation
DBS0235491amiB-amiBdecreased cAMP-induced cGMP pulse | abolished down-regulation of growth phase genes | decreased gene expression | abolished aggregation | decreased chemotaxis to cAMP | decreased cAMP-induced cAMP pulse
DBS0235493ampA-ampAdelayed tip formation | increased cell-cell adhesion | increased cell-substrate adhesion | mislocalized gene expression | delayed development | precocious gene expression | decreased prestalk cell differentiation | delayed gene expression
BS155amtA-amtAdecreased slug migration | decreased aggregate size | decreased fruiting body size | increased growth rate
DBS0267100amtA-amtAdecreased spore viability | decreased aggregate size | increased number of aggregates | decreased extracellular ammonia level | increased intracellular glucose level | decreased stalk length | increased intracellular ammonia level
BS165amtA-/ amtC-amtAaberrant slug migration | decreased localization of protein to the nucleus | delayed gene expression
BS165amtA-/ amtC-amtCaberrant slug migration | decreased localization of protein to the nucleus | delayed gene expression
BS154amtC-amtCdecreased gene expression | development arrests at slug stage | mislocalized gene expression | delayed culmination | aberrant protein localization | aberrant fruiting body morphology
DBS0235501amtC-/ [act15]: cudAamtCdelayed culmination
DBS0235501amtC-/ [act15]: cudAcudAdelayed culmination
DBS0235502amtC-/ [ecmA]: cudAamtCdelayed culmination
DBS0235502amtC-/ [ecmA]: cudAcudAdelayed culmination
DBS0235503amtC-/ [pspA]: cudAamtCdevelopment arrests at slug stage
DBS0235503amtC-/ [pspA]: cudAcudAdevelopment arrests at slug stage
DBS0236890amtC-/ regA-amtCprecocious sporulation
DBS0236890amtC-/ regA-regAprecocious sporulation
DBS0235505apm1-apm1aberrant contractile vacuole organization and biogenesis | decreased spore germination | aberrant response to hypo-osmotic stress | decreased growth rate | aberrant endosome morphology | delayed development | decreased stalk width
DBS0235509aprA-aprAincreased aggregate size | decreased spore viability | aberrant cytokinesis | increased growth rate | aberrant fruiting body morphology | decreased sporulation
DBS0235510aprA-/ actin15: : aprAaprAdecreased growth rate | aberrant fruiting body morphology
DBS0238124aqpA-aqpAdecreased spore viability
DBS0235511arkA-arkAincreased gene expression | aberrant fruiting body morphology
DBS0235512arkA-/ [arkA]: arkA: myc2arkAaberrant aggregation
HR131atg1-atg1abolished sporulation | decreased growth rate in suspension | abolished macroautophagy | increased number of autophagosomes | aberrant cellular response to nitrogen starvation | abolished stalk cell differentiation | abolished aggregation | decreased growth rate on bacterial plates
DBS0238092atg1-/ [act15]: atg1(1-628)atg1aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238087atg1-/ [act15]: atg1(K36A)atg1aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238089atg1-/ [act15]: atg1(K36A/ 1-628)atg1aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238093atg1-/ [act15]: atg1(P138S)atg1abolished aggregation
DBS0266655atg1-/ iplA-atg1decreased necrotic cell death
DBS0266655atg1-/ iplA-iplAdecreased necrotic cell death
HR75atg5-atg5aberrant macroautophagy | abolished sporulation | aberrant cellular response to nitrogen starvation | multiple tips | abolished aggregation
HR174 atg6-atg6Aaberrant macroautophagy | aberrant cellular response to nitrogen starvation | multiple tips | decreased fruiting body size | decreased stalk length | decreased sporulation
HR79atg7-atg7aberrant macroautophagy | abolished sporulation | aberrant cellular response to nitrogen starvation | multiple tips
HR141atg8-atg8aberrant macroautophagy | aberrant spore morphology | increased sensitivity to cisplatin | aberrant cellular response to nitrogen starvation | multiple tips | decreased fruiting body size | decreased sporulation
DBS0305977atg9-atg9increased stalk width | aberrant sorus morphology | decreased phagocytosis | decreased growth rate | aberrant slug migration | aberrant fruiting body morphology | aberrant slug formation | multiple tips in mound
TL97cadA-cadAmultiple tips | decreased sporulation | delayed culmination | increased prestalk cell differentiation
DBS0235563capB-truncatedcapBdecreased growth rate | delayed development
DBS0235568car4-carDincreased gene expression | decreased gene expression | aberrant fruiting body morphology
RI4carA-/ carC-carA-1decreased chemoattractant-mediated F-actin polymerization | decreased cAMP-induced cGMP pulse | abolished aggregation
RI4carA-/ carC-carA-2decreased chemoattractant-mediated F-actin polymerization | decreased cAMP-induced cGMP pulse | abolished aggregation
RI4carA-/ carC-carCdecreased chemoattractant-mediated F-actin polymerization | decreased cAMP-induced cGMP pulse | abolished aggregation
DBS0235570carB-carBdevelopment arrests at mound stage
DBS0235573carmil-carmildecreased pinocytosis | decreased growth rate | decreased basal F-actin level | decreased aggregate size
DBS0235574catB-catBspores hypersensitive to H2O2 (peroxide) | delayed development
DBS0304455cblA-cblA-1abolished basal disc formation | aberrant slug formation | aberrant signal transduction
DBS0304455cblA-cblA-2abolished basal disc formation | aberrant slug formation | aberrant signal transduction
DBS0235661cdk8-cdk8decreased gene expression | mislocalized gene expression | abolished aggregation
DBS0302444cfaD-cfaDincreased growth rate | aberrant fruiting body morphology
HO103chcA-chcAabolished sporulation | abolished cytokinesis | abolished gene expression | delayed aggregation | abolished growth in suspension | aberrant fruiting body morphology
DBS0235601clc-clcabolished cytokinesis | aberrant response to hypo-osmotic stress | abolished growth | aberrant fruiting body morphology
DBS0235604clc-/ [act15]: GFP-clc(146-194)clcabolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0235605clc-/ [act15]: GFP-clc(85-124)clcabolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0235607clc-/ [act15]GFP: clc(1-124)clcabolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0302655cnrN-cnrNaberrant streaming | increased cAMP-induced cAMP pulse | increased F-actin polymerization | increased number of aggregates
HG1770cnxA-cnxAdecreased extracellular Ca2+ uptake | increased cytosolic Ca2+ response
DBS0235617comB-comBabolished culmination
DG1016comB-comBabolished culmination
DBS0235618comC-comCaberrant streaming | aberrant aggregation
DBS0235619comD-comDabolished culmination
DBS0235620comE-comEtranslucent sorus | aberrant fruiting body morphology
DBS0235621comF-comF-1abolished aggregation
DBS0235621comF-comF-2abolished aggregation
DBS0235622comG-comGdevelopment arrests at mound stage | multiple tips
DBS0235623comH-comHdevelopment arrests at mound stage
TL55cotA-cotAaberrant spore coat morphology
TL53cotA-/ cotB-cotAaberrant spore coat morphology
TL53cotA-/ cotB-cotBaberrant spore coat morphology
TL56cotA-/ cotB-/ cotC-cotAaberrant spore coat morphology
TL56cotA-/ cotB-/ cotC-cotBaberrant spore coat morphology
TL56cotA-/ cotB-/ cotC-cotCaberrant spore coat morphology
TL57cotA-/ cotB-/ cotC-cotAaberrant spore coat morphology
TL57cotA-/ cotB-/ cotC-cotBaberrant spore coat morphology
TL57cotA-/ cotB-/ cotC-cotCaberrant spore coat morphology
TL54cotB-/ cotC-cotBaberrant spore coat morphology
TL54cotB-/ cotC-cotCaberrant spore coat morphology
TL52cotC-cotCaberrant spore coat morphology
HW07cotE(1-235)cotEaberrant spore coat morphology
DBS0238297cpnA-cpnAdelayed response to hypo-osmotic stress | decreased culmination | decreased growth rate | aberrant cytokinesis | delayed development | aberrant fruiting body morphology
DBS0238320cpnA-/ [act15]: GFP: cpnAcpnAdelayed response to hypo-osmotic stress | decreased culmination | delayed development
DBS0235627crlA-crlAincreased aggregate size | delayed tip formation | decreased sorting to prestalk region | increased growth rate
DBS0235628crlA-/ [crlA]: crlAcrlAincreased aggregate size
HG1768crtA-crtAdecreased extracellular Ca2+ uptake | increased cytosolic Ca2+ response
HG1772crtA-/ cnxA-cnxAdecreased growth rate in suspension | delayed response to cAMP | decreased extracellular Ca2+ uptake | decreased phagocytosis | increased cytosolic Ca2+ response | decreased growth rate on bacterial plates
HG1772crtA-/ cnxA-crtAdecreased growth rate in suspension | delayed response to cAMP | decreased extracellular Ca2+ uptake | decreased phagocytosis | increased cytosolic Ca2+ response | decreased growth rate on bacterial plates
DBS0235633crtf-crtfabolished sporulation | decreased gene expression | abolished aggregation
TL73csaA-/ csbA-/ csbC-/ csbC-csaAaberrant culminant morphology
TL73csaA-/ csbA-/ csbC-/ csbC-csbAaberrant culminant morphology
TL73csaA-/ csbA-/ csbC-/ csbC-csbBaberrant culminant morphology
TL73csaA-/ csbA-/ csbC-/ csbC-csbCaberrant culminant morphology
TL72csbA-/ csbB-/ csbC-csbAincreased resistance to cisplatin | aberrant culminant morphology
TL72csbA-/ csbB-/ csbC-csbBincreased resistance to cisplatin | aberrant culminant morphology
TL72csbA-/ csbB-/ csbC-csbCincreased resistance to cisplatin | aberrant culminant morphology
WTC127cshA-cshAdevelopment arrests at loose aggregate stage | decreased phagocytosis | decreased growth rate | delayed aggregation
DBS0235624ctnA-ctnAdecreased protein level | increased cAMP-induced cGMP pulse | increased aggregate size | decreased basal F-actin level | increased cell-cell adhesion | increased GTP-gamma-S-stimulated guanylyl cyclase activity | increased protein level | increased cell motility | increased intracellular glucose level | decreased cAMP-induced cAMP pulse | decreased myosin II assembly
DBS0235636ctnB-ctnBdecreased gene expression | increased number of aggregates | decreased fruiting body size
DG1071ctr9-ctr9aberrant fruiting body morphology
DG1058ctrA-ctrAdecreased fruiting body size
DBS0235639cudA-cudAabolished sporulation | decreased gene expression | development arrests at slug stage | abolished stalk cell differentiation
DBS0235640culA-culAmultiple tips | development arrests at tipped mound stage
DBS0235641culA-/ [cotC]: culAculAincreased sorus size | decreased stalk length | decreased sporulation
DBS0235642culA-/ [ecmA]: culAculAincreased sorus size | decreased stalk length
DBS0266745culB-culBdecreased fruiting body size | precocious gene expression | aberrant slug formation | decreased sporulation | multiple tips in mound
DBS0266761culB-/ [act15]: pkaCculBabolished gene expression | abolished sporulation | precocious gene expression | abolished aggregation
DBS0266761culB-/ [act15]: pkaCpkaCabolished gene expression | abolished sporulation | precocious gene expression | abolished aggregation
DBS0266760culB-/ pkaR-culBabolished gene expression | abolished sporulation | precocious gene expression | abolished aggregation
DBS0266760culB-/ pkaR-pkaRabolished gene expression | abolished sporulation | precocious gene expression | abolished aggregation
DBS0235651cybA-cybAabolished sporulation | aberrant development
AK108dagA-dagAabolished gene expression | decreased gene expression | abolished activation of adenylate cyclase | abolished aggregation
DBS0235653darA-darAdecreased cell polarity | decreased cell motility | decreased aggregate size | abolished aggregation
DG1099dcsA-dcsAabolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | abolished stalk formation | abolished stalk cell differentiation
DG1128dcsA-dcsAabolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | abolished stalk formation
TL127dcsA-dcsAabolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | aberrant stalk formation | abolished stalk formation | abolished stalk cell differentiation
DBS0349804detA-detAincreased aggregate size | decreased growth rate | delayed development
DBS0349813detA-/ [cotB]: GFPdetAdecreased prespore cell differentiation
DBS0349811detA-/ [ecm0]: lacZdetAaberrant prestalk O cell differentiation
DBS0349812detA-/ [ecmA0]: GFPdetAincreased prestalk cell differentiation
DBS0349808detA-/ [ecmA0]: lacZdetAincreased prestalk cell differentiation
DBS0349809detA-/ [ecmA]: lacZdetAincreased prestalk A cell differentiation
DBS0349810detA-/ [ecmB]: lacZdetAdelayed development
DBS0235695dgkA-dgkAdecreased spore viability | increased myosin II assembly | decreased chemotaxis rate | aberrant development
AK299dhkA-dhkAaberrant stalk morphogenesis | increased sporulation in the presence of 8-Br-cAMP | increased gene expression | mislocalized gene expression | decreased sporulation | aberrant fruiting body morphology
TL134dhkA-/ dhkB-dhkAabolished sporulation | increased stalk length | decreased stalk width
TL134dhkA-/ dhkB-dhkBabolished sporulation | increased stalk length | decreased stalk width
HR49dhkA-/ fbxA-dhkAdecreased intracellular cAMP level | aberrant fruiting body morphology | decreased sporulation
HR49dhkA-/ fbxA-fbxAdecreased intracellular cAMP level | aberrant fruiting body morphology | decreased sporulation
HR51dhkA-/ fbxA-dhkAaberrant fruiting body morphology | decreased sporulation
HR51dhkA-/ fbxA-fbxAaberrant fruiting body morphology | decreased sporulation
HR50dhkA-/ fbxA-dhkAabolished culmination | decreased sporulation
HR50dhkA-/ fbxA-fbxAabolished culmination | decreased sporulation
DBS0235704dhkB-dhkBprecocious spore germination
TL135dhkC-dhkCprecocious culmination | decreased spore germination | precocious aggregation | precocious development
DBS0235710dhkK-dhkKaberrant slug migration | delayed culmination | delayed gene expression
DBS0235712dhkK-/ [act15]: dhkK(D1125N)dhkKaberrant fruiting body morphology
DBS0235714dhkK-/ regA-dhkKprecocious development
DBS0235714dhkK-/ regA-regAprecocious development
DBS0348046dhkM-dhkMabolished autophagic vacuole formation | delayed development
DBS0348047dhkM-dhkMabolished autophagic vacuole formation | delayed development
DBS0235719dia1-/ [act6]: trap1dia1aberrant aggregation | decreased fruiting body size
DBS0235719dia1-/ [act6]: trap1trap1aberrant aggregation | decreased fruiting body size
DBS0235895dimA-dimAthin fingers | long fingers | abolished prestalk cell differentiation | increased slug size | increased prespore cell differentiation | decreased prestalk O cell differentiation | aberrant fruiting body morphology
DBS0235899dimA-/ dimB-dimAthin fingers | long fingers | increased slug size
DBS0235899dimA-/ dimB-dimBthin fingers | long fingers | increased slug size
DBS0235902dimB-/ [cotB]: lacZdimBincreased prespore cell differentiation
DBS0235906dimB-/ [ecmAO]: lacZdimBdecreased prestalk O cell differentiation
DBS0235907dimB-/ [ecmO]: lacZdimBaberrant prestalk cell differentiation
DBS0235913dmpA-dmpAaberrant streaming | translucent sorus | delayed development | decreased stalk cell differentiation | decreased sporulation | aberrant fruiting body morphology
HM1030dmtA-dmtAthin fingers | decreased outer basal disc size | abolished prestalk O cell differentation | abolished DIF production | delayed tip formation | decreased lower cup size | delayed development | decreased prestalk O cell differentiation | aberrant fruiting body morphology | decreased prestalk cell differentiation
HM1196dmtA-/ stlA-dmtAdecreased outer basal disc size | decreased prestalk O cell differentiation
HM1196dmtA-/ stlA-stlBdecreased outer basal disc size | decreased prestalk O cell differentiation
DBS0235915dng1-dng1decreased growth rate | delayed aggregation
DBS0235916dnmA-dnmAaberrant culminant morphology | translucent sorus | decreased cytosine methylation in genomic DNA | decreased sporulation
DG2015docA-docAdevelopment arrests at mound stage
DBS0235920dokA-dokAaberrant response to hyperosmotic stress | translucent sorus | decreased sporulation
DBS0349789dotA-dotAdecreased growth rate | increased sensitivity to UV light | decreased spore size | delayed development | abolished histone H3-K79 methylation
DBS0235925dstA-dstAabolished gene expression | increased gene expression | decreased gene expression | delayed aggregation | mislocalized gene expression | decreased cell motility | abolished stalk cell differentiation | abolished sorting to prestalk region | aberrant fruiting body morphology
DBS0235926dstA-dstAdelayed aggregation | mislocalized gene expression | decreased cell motility | abolished stalk cell differentiation | abolished sorting to prestalk region | aberrant fruiting body morphology
DBS0238237dstA-/ GFP: dstA(237-707): ORF+dstAabolished culmination | decreased stalk length
DBS0238236dstA-/ GFP: dstA(237-707): ORF+/ [OE]dutA(751-1322)dstAdecreased stalk length
DBS0238236dstA-/ GFP: dstA(237-707): ORF+/ [OE]dutA(751-1322)dutAdecreased stalk length
DBS0252824dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 2C2Caberrant fruiting body morphology
DBS0252824dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 2CdstAaberrant fruiting body morphology
DBS0252826dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0276165DDB_G0276165aberrant fruiting body morphology
DBS0252826dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0276165dstAaberrant fruiting body morphology
DBS0252825dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0282325DDB_G0282325aberrant fruiting body morphology
DBS0252825dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0282325dstAaberrant fruiting body morphology
DBS0235937dtfA-dtfAdelayed tip formation | aberrant cytokinesis | aberrant fruiting body morphology
DBS0347874dymA-dymAdecreased pinocytosis | aberrant cell separation during cytokinesis | decreased cell polarity | aberrant mitochondrion morphology | increased cell size | increased basal disc size | decreased growth rate | aberrant stalk formation | aberrant nucleus morphology | aberrant endosome morphology | delayed development | aberrant pseudopod formation | increased phagocytosis | aberrant fruiting body morphology
HJW117ecmA-ecmAthin fingers | weak slime trail | long fingers
DBS0235946egeB-egeBdevelopment arrests at mound stage
DBS0302590elmoA-elmoAdecreased culmination | increased pseudopod formation | increased localization of protein to the pseudopodium | increased F-actin polymerization | decreased cell motility | delayed development | abolished cell polarity | increased phagocytosis
DBS0302448epnA-epnAaberrant spore morphology | decreased spore viability | aberrant cytokinesis | abolished protein phosphorylation | aberrant protein localization
DBS0302457epnA-/ [act15]: GFP: epnA(253-677)epnAabolished localization of protein to the plasma membrane | aberrant spore morphology | abolished localization of protein to coated pits
DBS0302474epnA-/ [act15]: epnA(R65A/ K78A): GFPepnAabolished localization of protein to the plasma membrane | aberrant spore morphology | abolished phosphatidylinositol-4,5-bisphosphate binding | abolished localization of protein to coated pits
DBS0302475epnA-/ [act15]: epnA(T107A): GFPepnAaberrant spore morphology
DBS0235947eppA-eppAdecreased growth rate | delayed development | decreased chemotaxis to folate | decreased chemotaxis to cAMP | decreased intracellular cAMP level
HS174erkB-erkBdecreased cell motility | abolished aggregation | decreased chemotaxis to cAMP | decreased cAMP-induced cAMP pulse | decreased sporulation
AK240erkB-erkBabolished aggregation | decreased cAMP-induced cAMP pulse | decreased sporulation
DBS0235949erkB-/ regA-erkBincreased cAMP-induced cAMP pulse | abolished aggregation
DBS0235949erkB-/ regA-regAincreased cAMP-induced cAMP pulse | abolished aggregation
DBS0235953fbxA-fbxAdecreased sporulation
DBS0235954fbxA-/ [ecmA]: GFP(S65T)fbxAincreased prespore cell differentiation
HR46fbxA-/ regA-fbxAaberrant fruiting body morphology | decreased sporulation
HR46fbxA-/ regA-regAaberrant fruiting body morphology | decreased sporulation
HR48fbxA-/ regA-fbxAaberrant fruiting body morphology | decreased sporulation
HR48fbxA-/ regA-regAaberrant fruiting body morphology | decreased sporulation
DBS0235956fbxA1-fbxAdevelopment arrests at slug stage | increased slug migration | aberrant fruiting body morphology | delayed culmination
DBS0235957fbxA2-fbxAdevelopment arrests at slug stage | increased slug migration | aberrant fruiting body morphology | delayed culmination
DBS0235958fbxA3-fbxAdevelopment arrests at slug stage | increased slug migration | aberrant fruiting body morphology | delayed culmination
DG1148fcpA-fcpAaberrant fruiting body morphology
DBS0235969forC-forCaberrant culmination | development arrests at tipped mound stage | aberrant fruiting body morphology
DBS0302506frmA-frmAdelayed aggregation | decreased cell motility | increased cell-substrate adhesion | decreased aggregate size | aberrant cell morphology
DBS0304440frmA-/ [unk]: GFPfrmAdecreased gene expression | increased cell-cell adhesion | delayed development | aberrant development | abolished phototaxis
DG1066fut1-fut1aberrant fruiting body morphology
DBS0305025gabT-gabTprecocious development | decreased sporulation
DG1094gacT-gacTaberrant fruiting body morphology
DBS0235989gadA-gadAabolished SDF production | decreased sporulation
TL198gbfA-gbfAabolished gene expression | development arrests at mound stage
DBS0305094gbfA-gbfAabolished autophagic cell death | abolished autophagic vacuole formation
DBS0235994gbpC-gbpCdecreased myosin light chain kinase activation | decreased fruiting body size
DBS0235995gbpC-gbpCdecreased cell polarity | aberrant myosin II organization | decreased chemotaxis rate | aberrant cell morphology | decreased fruiting body size
DBS0302680gbpC-gbpCdecreased aggregate size | abolished aggregation
DBS0235998gbpD-/ [act15]: gbpDgbpDaberrant F-actin organization | increased cell-substrate adhesion | increased lateral pseudopod formation | decreased chemotaxis rate | abolished aggregation
DG1120gbqA-gbqAaberrant fruiting body morphology
DBS0302679gca-/ sgcA-gcAaberrant streaming | aberrant chemotaxis to cAMP | increased lateral pseudopod formation | decreased chemotaxis rate | decreased aggregate size | decreased fruiting body size
DBS0302679gca-/ sgcA-sgcAaberrant streaming | aberrant chemotaxis to cAMP | increased lateral pseudopod formation | decreased chemotaxis rate | decreased aggregate size | decreased fruiting body size
DBS0236002gcsA-gcsAabolished gene expression | development arrests at mound stage | inviable | cell cycle arrest | spores inviable
DBS0236003gcsA-/ [act15]: gcsAgcsAdecreased spore viability | development arrests at mound stage
DBS0236004gdt1-gdt1decreased growth rate in suspension | increased gene expression | precocious aggregation
DBS0237190gdt1-/ [act15]: pkaR(G135E/ G261A)gdt1increased gene expression | abolished aggregation
DBS0237190gdt1-/ [act15]: pkaR(G135E/ G261A)pkaRincreased gene expression | abolished aggregation
DBS0236095gdt1-/ gpaB-gdt1increased gene expression | abolished aggregation
DBS0236095gdt1-/ gpaB-gpaBincreased gene expression | abolished aggregation
DBS0236006gdt2-gdt2increased gene expression | precocious aggregation
RI19gefA-gefAdecreased chemoattractant-mediated F-actin polymerization | decreased cAMP-induced cGMP pulse | decreased chemotaxis rate | abolished activation of adenylate cyclase | abolished aggregation | decreased cAMP-induced cAMP pulse
JB10gefA-gefAabolished aggregation
DBS0236009gefB-gefBaberrant cytoskeleton organisation | abolished pinocytosis | increased basal F-actin level | abolished growth | delayed aggregation | decreased phagocytosis | decreased growth rate | decreased aggregate size | aberrant cell morphology | aberrant fruiting body morphology
HSB61gefM-gefMincreased cAMP-induced cGMP pulse | aberrant activation of adenylate cyclase activity | development arrests at mound stage | decreased chemotaxis rate | decreased lateral pseudopod suppression | decreased cAMP-induced cAMP pulse
DBS0304968gefQ-gefQabolished Ras guanyl-nucleotide exchange factor activity | increased myosin II assembly | increased lateral pseudopod formation | abolished sorting to prestalk region | decreased fruiting body size | abolished phototaxis | multiple tips in mound
DG1109ggtA-ggtAaberrant fruiting body morphology
DBS0266723glcS-/ DH1glcSaberrant stalk morphogenesis | decreased spore size | decreased intracellular glycogen level | decreased fruiting body size
DBS0236079gmsA-gmsAdecreased sexual fusion
DBS0236080gmsA-gmsAdecreased sexual fusion
DBS0238382gnt15-gnt15decreased gene expression | decreased growth rate | increased calcium-independent cell-cell adhesion | abolished aggregation | abolished culmination
DBS0238383gnt15-gnt15decreased gene expression | decreased growth rate | increased calcium-independent cell-cell adhesion | abolished aggregation | abolished culmination
DBS0236087gpaA-gpaAincreased stalk length | decreased stalk width
DBS0236092gpaA-/ [gpaA]: gpaA(G45V)gpaAdelayed development
DBS0236093gpaA-/ [gpaA]: gpaA(Q206L)gpaAincreased basal disc size
DBS0238605gpaA-/ rpkA-gpaAdelayed aggregation | abolished aggregation
DBS0238605gpaA-/ rpkA-rpkAdelayed aggregation | abolished aggregation
DBS0236575gpaB-gpaBdecreased cAMP-induced cGMP pulse | decreased cAMP-induced cAMP pulse
JH104gpaB-gpaBdecreased gene expression | abolished activation of adenylate cyclase | abolished aggregation
DBS0236096gpaB-/ [act15]: gpaBgpaBabolished aggregation
DBS0266942gpaB-/ [act15]: gpaBgpaBdelayed aggregation
DBS0266939gpaB-/ [act15]: gpaB(1-345): gpaD(337-345)gpaBabolished aggregation
DBS0266939gpaB-/ [act15]: gpaB(1-345): gpaD(337-345)gpaDabolished aggregation
DBS0237137gpaB-/ [act15]: gpaB(D154V)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237138gpaB-/ [act15]: gpaB(E190G)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased cAMP-induced cAMP pulse
DBS0237139gpaB-/ [act15]: gpaB(I104S)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237140gpaB-/ [act15]: gpaB(L110S)gpaBaberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237141gpaB-/ [act15]: gpaB(L76P)gpaBabolished aggregation
DBS0237142gpaB-/ [act15]: gpaB(N74D)gpaBdecreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | abolished aggregation | decreased cAMP-induced cAMP pulse
DBS0237143gpaB-/ [act15]: gpaB(R64G)gpaBdecreased chemotaxis rate | abolished aggregation
DBS0237144gpaB-/ [act15]: gpaB(S155P)gpaBdecreased chemotaxis rate | abolished aggregation
DBS0236097gpaB-/ [gpaA]: gpaBgpaBabolished aggregation
DBS0235986gpaC-gpaCincreased protein kinase A activity | aberrant activation of adenylate cyclase activity | decreased gene expression | abolished aggregation
JH417gpaD-gpaDdecreased gene expression | abolished SDF production | decreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology | decreased sporulation
DBS0266944gpaD-/ [act15]: gpaBgpaBdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266944gpaD-/ [act15]: gpaBgpaDdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266946gpaD-/ [act15]: gpaB(1-345): gpaD(337-345)gpaBdecreased accumulation of cGMP | aberrant fruiting body morphology
DBS0266946gpaD-/ [act15]: gpaB(1-345): gpaD(337-345)gpaDdecreased accumulation of cGMP | aberrant fruiting body morphology
DBS0266945gpaD-/ [act15]: gpaEgpaDdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266945gpaD-/ [act15]: gpaEgpaEdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266947gpaD-/ [act15]: gpaE(1-339): gpaD(337-345)gpaDdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266947gpaD-/ [act15]: gpaE(1-339): gpaD(337-345)gpaEdecreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
JH257gpaE-gpaEdelayed tip formation | delayed gene expression
DBS0266941gpaE-/ [act15]: gpaEgpaEprecocious tip formation
DBS0266948gpaE-/ [act15]: gpaE(1-339): gpaD(337-345)gpaDprecocious tip formation
DBS0266948gpaE-/ [act15]: gpaE(1-339): gpaD(337-345)gpaEprecocious tip formation
DBS0236109gpaI-gpaIprecocious aggregation | decreased aggregate size | increased number of aggregates | decreased fruiting body size
LW5gpbA-gpbAabolished aggregation
LW6gpbA-gpbAdecreased CRAC localization to the plasma membrane | decreased positive regulation of Ras GTPase activity | decreased cAMP-induced cGMP pulse | decreased chemotaxis to folate | decreased chemotaxis to cAMP | decreased cAMP-induced cAMP pulse | aberrant protein localization
DBS0304814grlA-grlAdecreased gene expression | abolished SDF production | decreased number of spores | delayed gene expression | delayed culmination
DBS0304815grlA-/ [act15]: grlA: GFPgrlAaberrant tip formation
DBS0236112grlE-grlEabolished SDF production | aberrant gamma-aminobutyric acid signaling pathway | decreased sporulation
DBS0236113grlE-grlEdelayed aggregation | aberrant gene expression | decreased chemotaxis to cAMP
DBS0238865grlJ-grlJaberrant spore morphology | decreased spore viability | increased slug size | precocious development | decreased fruiting body size | precocious gene expression
DBS0238686grpA-grpAdecreased spore germination | abolished protein secretion
ARK200gskA-gskAincreased gene expression | decreased gene expression | decreased chemotaxis to cAMP | abolished streaming | decreased sporulation
DBS0236114gskA-gskAdecreased slug migration | aberrant sorus morphology | decreased stalk length
HM338gskA-gskAprecocious aggregation | decreased prespore cell differentiation | aberrant fruiting body morphology | increased prestalk cell differentiation | decreased sporulation
DBS0266891gtaC-gtaCabolished stalk cell differentiation in vitro | aberrant streaming | decreased aggregate size | aberrant prestalk B cell differentiation
DBS0236120gxcA-gxcAdecreased chemoattractant-mediated F-actin polymerization | delayed development | decreased positive regulation of Rac GTPase activity
DBS0236121gxcB-gxcBdecreased exocytosis | aberrant cytoskeleton organisation | delayed development
DBS0238825gxcDD-gxcDDaberrant streaming | delayed development
DBS0236131hbx2-/ warA-hbx2increased basal disc size | development arrests at mound stage | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0236131hbx2-/ warA-warAincreased basal disc size | development arrests at mound stage | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0305109hdaB-hdaBdecreased sporulation | decreased histone deacetylase activity
HM1012helC-helCdecreased gene expression | delayed development | aberrant fruiting body morphology
HM444helC-helCdecreased gene expression | delayed development | aberrant fruiting body morphology
DG1059helE-helEincreased slug migration
DBS0236163helF-helFincreased stalk cell differentiation | increased slug size | delayed development | increased gene silencing by RNA interference
DBS0238583hipA-hipAaberrant spore morphology | decreased spore viability | aberrant spore coat morphology
DBS0305951hipA-/ epnA-epnAaberrant spore morphology | decreased spore viability
DBS0305951hipA-/ epnA-hipAaberrant spore morphology | decreased spore viability
DBS0349776htt-httdecreased growth rate in suspension | aberrant cell separation during cytokinesis | decreased chemotaxis rate | delayed development | delayed gene expression | decreased myosin II assembly
DBS0349788htt-httaberrant aggregation | development arrests at loose aggregate stage | aberrant spore morphology | decreased spore viability | aberrant response to hypo-osmotic stress | aberrant F-actin organization | decreased number of spores | aberrant response to starvation | abolished streaming | aberrant development | multiple tips in mound | aberrant prespore cell differentiation | abolished calcium-independent cell-cell adhesion
DBS0349794ibrA-ibrAaberrant stalk formation
DBS0252699icmA-icmA-1abolished sporulation | aberrant signal transduction during aggregation | abolished growth | development arrests at mound stage | abolished cell polarity | abolished streaming | aberrant cAMP wave formation | delayed gene expression | aberrant fruiting body morphology | aberrant protein localization
DBS0252699icmA-icmA-2abolished sporulation | aberrant signal transduction during aggregation | abolished growth | development arrests at mound stage | abolished cell polarity | abolished streaming | aberrant cAMP wave formation | delayed gene expression | aberrant fruiting body morphology | aberrant protein localization
BS153ifkA-ifkAincreased aggregate size | precocious aggregation | decreased extracellular counting factor component(s) level | precocious gene expression
BS161ifkA-/ ifkB-ifkAincreased aggregate size | increased cell-cell adhesion | increased cell-substrate adhesion | aberrant fruiting body morphology | multiple tips in mound
BS161ifkA-/ ifkB-ifkBincreased aggregate size | increased cell-cell adhesion | increased cell-substrate adhesion | aberrant fruiting body morphology | multiple tips in mound
DBS0236425ino1-ino1decreased intracellular myo-inositol level | abolished growth | decreased phagocytosis | increased intracellular 2,3-bisphosphoglycerate level | multiple tips in mound
DBS0266326iplA-iplAabolished cellulose biosynthesis | abolished autophagic vacuole formation | abolished autophagic cell death
HM1038iplA-iplAabolished cAMP-induced Ca2+ influx | precocious aggregation | delayed aggregation | increased chemotaxis to arachidonic acid
DBS0252878iptA-iptAdecreased spore viability
DBS0238720krsA-krsAaberrant response to hyperosmotic stress | precocious culmination | abolished activation of adenylate cyclase | decreased aggregate size | decreased intracellular cAMP level | precocious gene expression | abolished streaming | decreased cell size
DBS0238722krsA-/ [act15]: GFP: krsA(K49R)krsAaberrant streaming
DBS0238723krsA-/ [act15]: GFP: krsA(T173A)krsAabolished streaming
DBS0238725krsA-/ [act15]: GFP: krsA(deltaC)krsAaberrant streaming
DBS0238724krsA-/ [act15]: GFP: krsA(deltaKinase)krsAabolished streaming
DBS0238726krsA-/ [act15]: GFP: krsA(deltaNS)krsAabolished streaming
AK127lagC-tgrC1development arrests at loose aggregate stage | aberrant aggregation | increased aggregate size
DBS0236498lagD-tgrD1aberrant aggregation | aberrant cAMP signaling during aggregation | abolished streaming
DBS0236499limB-limBdecreased cell polarity | decreased cell-substrate adhesion | decreased gene expression | development arrests at mound stage | aberrant F-actin organization | aberrant cell-cell adhesion | decreased chemotaxis rate | abolished sorting to prestalk region | delayed gene expression
DBS0236502limB-/ [act15]: paxB: GFPlimBdevelopment arrests at mound stage
DBS0236502limB-/ [act15]: paxB: GFPpaxBdevelopment arrests at mound stage
DBS0236500limB-/ [cotC]: limBlimBdevelopment arrests at mound stage
DBS0236729limB-/ paxB-limBdevelopment arrests at mound stage
DBS0236729limB-/ paxB-paxBdevelopment arrests at mound stage
DG1006lipA-lipAabolished culmination
DG1056lipB-captCaberrant fruiting body morphology
DBS0236516lrrA-lrrAdecreased cell polarity | increased aggregate size | decreased cell-substrate adhesion | increased basal F-actin level | decreased spore viability | abolished chemotaxis | decreased gene expression | development arrests at mound stage | abolished aggregation | aberrant cell morphology | delayed gene expression
DBS0236517lst8-lst8decreased F-actin polymerization | aberrant activation of adenylate cyclase activity | decreased chemotaxis rate | abolished aggregation | decreased myosin II assembly
AD63lvsA-lvsAabolished cytokinesis | abolished cAMP-induced Ca2+ influx
HMW404manA-manAabolished aggregation
DBS0236543mekA-mekAdecreased aggregate size | precocious development
DBS0238098mekA-/ ppp4C-mekAdecreased aggregate size
DBS0238098mekA-/ ppp4C-ppp4cdecreased aggregate size
DBS0238109mekA-/ ppp4C-/ [act15]: FLAG: pppCppp4cdecreased aggregate size | precocious development
DBS0236542mekA-/ smkA-mekAdecreased aggregate size
DBS0236542mekA-/ smkA-smkAdecreased aggregate size
DBS0266843mgp1-mgp1aberrant contractile vacuole organization and biogenesis | increased phototaxis | increased filopodium formation | decreased cell motility | decreased fruiting body size | abolished streaming | decreased stalk width | decreased stalk length
DBS0266846mgp1-/ mgp2-mgp1aberrant contractile vacuole organization and biogenesis | increased filopodium formation | aberrant culmination | decreased cell motility | decreased phototaxis | decreased stalk length
DBS0266846mgp1-/ mgp2-mgp2aberrant contractile vacuole organization and biogenesis | increased filopodium formation | aberrant culmination | decreased cell motility | decreased phototaxis | decreased stalk length
DBS0266844mgp2-mgp2increased aggregate size | increased slug size
HS2207mhcA-mhcAabolished cytokinesis | development arrests at mound stage
DBS0238158mhcA-/ [act15]: mhcA(81-2116)mhcAdecreased growth rate | development arrests at tipped mound stage
DBS0236552mhcA-/ [mhcA]: mhcA(1-1224)mhcAaberrant cytokinesis | development arrests at mound stage
DBS0236557mhkA-/ [act15]: mhkAmhkAdecreased growth rate in suspension | development arrests at mound stage | aberrant cytokinesis | decreased myosin II assembly
DG1069mhkC-mhkCaberrant fruiting body morphology
DBS0236559midA-midAdecreased growth rate in suspension | aberrant spore morphology | decreased thermotaxis | increased intracellular glutamate level | decreased intracellular glycogen level | increased extracellular ammonia level | increased slug migration | decreased growth rate on bacterial plates | decreased cell size | decreased phototaxis
DG1020migA-migAabolished slug migration | decreased fruiting body size | aberrant fruiting body morphology
DBS0236561mkcA-/ tagB-mkcAdecreased sporulation
DBS0236561mkcA-/ tagB-tagBdecreased sporulation
DBS0236562mkcA-/ tagC-mkcAdecreased sporulation
DBS0236562mkcA-/ tagC-tagCdecreased sporulation
DG1101mkcB-mkcBdecreased fruiting body size
DBS0236564mkkA-mkkAprecocious culmination | decreased sorus size | increased stalk length
DG1121mkpA-mkpAabolished aggregation
DBS0236566mlcE-mlcEdecreased growth rate in suspension | aberrant cytokinesis | delayed aggregation | decreased cell motility | mislocalized gene expression | aberrant development
DBS0236567mlcR-mlcRaberrant myosin II organization | aberrant cytokinesis | development arrests at mound stage
DG1033modA-modAaberrant fruiting body morphology
DBS0266903mpl1-mpl1decreased cell motility | decreased chemotaxis to cAMP | abolished streaming | abolished aggregation
DBS0236569mrps4-mrps4delayed aggregation | aberrant fruiting body morphology
DBS0304881mrps4-mrps4delayed aggregation
DBS0304882mtDNA-DidioMp05abolished growth | abolished aggregation
DBS0304882mtDNA-DidioMp21abolished growth | abolished aggregation
DBS0304882mtDNA-DidioMp26abolished growth | abolished aggregation
DBS0304882mtDNA-DidioMp27abolished growth | abolished aggregation
DBS0304882mtDNA-DidioMp30abolished growth | abolished aggregation
DBS0304882mtDNA-DidioMp35abolished growth | abolished aggregation
DBS0304882mtDNA-DidioMp36abolished growth | abolished aggregation
DBS0304882mtDNA-ai2aabolished growth | abolished aggregation
DBS0304882mtDNA-ai2babolished growth | abolished aggregation
DBS0304882mtDNA-ai3abolished growth | abolished aggregation
DBS0304882mtDNA-ai4abolished growth | abolished aggregation
DBS0304882mtDNA-atp1abolished growth | abolished aggregation
DBS0304882mtDNA-atp6abolished growth | abolished aggregation
DBS0304882mtDNA-atp9abolished growth | abolished aggregation
DBS0304882mtDNA-cox1/ 2abolished growth | abolished aggregation
DBS0304882mtDNA-cox3abolished growth | abolished aggregation
DBS0304882mtDNA-cytBabolished growth | abolished aggregation
DBS0304882mtDNA-mrpl11abolished growth | abolished aggregation
DBS0304882mtDNA-mrpl14abolished growth | abolished aggregation
DBS0304882mtDNA-mrpl16abolished growth | abolished aggregation
DBS0304882mtDNA-mrpl2abolished growth | abolished aggregation
DBS0304882mtDNA-mrpl6abolished growth | abolished aggregation
DBS0304882mtDNA-mrps12abolished growth | abolished aggregation
DBS0304882mtDNA-mrps13abolished growth | abolished aggregation
DBS0304882mtDNA-mrps14abolished growth | abolished aggregation
DBS0304882mtDNA-mrps19abolished growth | abolished aggregation
DBS0304882mtDNA-mrps2abolished growth | abolished aggregation
DBS0304882mtDNA-mrps4abolished growth | abolished aggregation
DBS0304882mtDNA-mrps7abolished growth | abolished aggregation
DBS0304882mtDNA-mrps8abolished growth | abolished aggregation
DBS0304882mtDNA-nad1abolished growth | abolished aggregation
DBS0304882mtDNA-nad11abolished growth | abolished aggregation
DBS0304882mtDNA-nad2abolished growth | abolished aggregation
DBS0304882mtDNA-nad3abolished growth | abolished aggregation
DBS0304882mtDNA-nad4abolished growth | abolished aggregation
DBS0304882mtDNA-nad4Labolished growth | abolished aggregation
DBS0304882mtDNA-nad5abolished growth | abolished aggregation
DBS0304882mtDNA-nad6abolished growth | abolished aggregation
DBS0304882mtDNA-nad7abolished growth | abolished aggregation
DBS0304882mtDNA-nad9abolished growth | abolished aggregation
DBS0304882mtDNA-rnlAabolished growth | abolished aggregation
DBS0236570mybB-mybBdecreased cAMP-induced cGMP pulse | decreased gene expression | decreased activation of adenylate cyclase | abolished aggregation | decreased cAMP-induced cAMP pulse
DBS0236571mybB-mybBabolished aggregation
HM388mybC-mybCdecreased SDF production | decreased gene expression | abolished culmination
DBS0236572mybE-mybEincreased slug size | abolished outer basal disc formation
DBS0237709mybE-/ [mrrA]: lacZmrrAaberrant prestalk cell differentiation
DBS0237709mybE-/ [mrrA]: lacZmybEaberrant prestalk cell differentiation
DBS0236573mybE-/ mybE: GFPmybEwild type | aberrant prestalk cell differentiation
HDT1myoA-myoAdelayed aggregation | decreased cell motility | decreased chemotaxis rate | decreased lateral pseudopod suppression
HDT5myoA-/ myoBmyoAdecreased pinocytosis | decreased growth rate in suspension | aberrant cytoskeleton organisation | increased secretion of lysosomal enzyme | decreased cell motility | decreased fruiting body size
HDT5myoA-/ myoBmyoBdecreased pinocytosis | decreased growth rate in suspension | aberrant cytoskeleton organisation | increased secretion of lysosomal enzyme | decreased cell motility | decreased fruiting body size
DBS0236580myoB-myoBdecreased phagocytosis | delayed aggregation | decreased cell motility | decreased lateral pseudopod suppression
DBS0236583myoB-/ [AS]myoDmyoBdecreased pinocytosis | aberrant aggregation | decreased growth rate | decreased phagocytosis | decreased cell motility | decreased aggregate size
DBS0236583myoB-/ [AS]myoDmyoDdecreased pinocytosis | aberrant aggregation | decreased growth rate | decreased phagocytosis | decreased cell motility | decreased aggregate size
DBS0236584myoB-/ [AS]myoD/ [KD]myoCmyoBsmall pinosomes | decreased pinocytosis | aberrant aggregation | decreased growth rate | decreased phagocytosis | decreased cell motility | increased number of pinosomes | decreased aggregate size
DBS0236584myoB-/ [AS]myoD/ [KD]myoCmyoCsmall pinosomes | decreased pinocytosis | aberrant aggregation | decreased growth rate | decreased phagocytosis | decreased cell motility | increased number of pinosomes | decreased aggregate size
DBS0236584myoB-/ [AS]myoD/ [KD]myoCmyoDsmall pinosomes | decreased pinocytosis | aberrant aggregation | decreased growth rate | decreased phagocytosis | decreased cell motility | increased number of pinosomes | decreased aggregate size
HDT6myoB-/ myoC-myoBincreased secretion of lysosomal enzyme | decreased growth rate in suspension | aberrant cytoskeleton organisation | decreased fruiting body size
HDT6myoB-/ myoC-myoCincreased secretion of lysosomal enzyme | decreased growth rate in suspension | aberrant cytoskeleton organisation | decreased fruiting body size
DBS0236589myoI-myoIdecreased spore germination
DBS0349844myoK-myoKaberrant cortical actin cytoskeleton stabilization | delayed aggregation | decreased phagocytosis | aberrant engulfment during phagocytosis | decreased chemotaxis rate | aberrant cell morphology
HC476ncsA-ncsAincreased intracellular cAMP level | precocious gene expression | precocious development
HC477ncsA-ncsAincreased intracellular cAMP level | precocious gene expression | precocious development
DBS0304633nfaA-nfaAaberrant localization of protein to the plasma membrane | increased pseudopod formation | increased chemoattractant-mediated F-actin polymerization | increased basal F-actin level | delayed aggregation | decreased cell motility | aberrant cAMP signaling during aggregation | aberrant regulation of Ras GTPase activity | aberrant regulation of protein kinase activity | decreased chemotaxis to cAMP
DBS0236606nosA null (15-S-12)nosAdevelopment arrests at mound stage
DBS0236607nosA null (2E4)nosAdevelopment arrests at mound stage
DBS0235950nosA-nosAdevelopment arrests at mound stage
DBS0236608noxA-noxAabolished sporulation | aberrant development
DBS0236611noxA-/ [act15]: noxA: myc2noxAaberrant fruiting body morphology
DBS0236610noxA-/ noxBnoxAabolished sporulation | decreased superoxide production | aberrant development
DBS0236610noxA-/ noxBnoxBabolished sporulation | decreased superoxide production | aberrant development
DBS0236612noxB-noxBabolished sporulation | decreased superoxide production | aberrant development
DBS0236613noxC-noxCabolished sporulation | aberrant development
DBS0236955nxnA-nxnAdecreased culmination | decreased growth rate | delayed development | decreased chemotaxis to cAMP | decreased lysosomal enzyme activity
DBS0236702nxnA-/ [act15]: GFP: nxnB nxnAdevelopment arrests at mound stage
DBS0236702nxnA-/ [act15]: GFP: nxnB nxnBdevelopment arrests at mound stage
DBS0236704osbA-osbAincreased slug migration | precocious development
DBS0304465padA(1-276)padAaberrant streaming | development arrests at slug stage | delayed aggregation | aberrant stalk cell differentiation | delayed development | aberrant fruiting body morphology
DBS0236705pakA-pakAaberrant cytokinesis | delayed development
DBS0236728paxB-paxBdecreased cell-substrate adhesion | decreased gene expression | abolished slug migration | development arrests at mound stage | decreased sorting to prestalk region | aberrant fruiting body morphology
DBS0236730paxB-/ [ecmA]: paxB: GFPpaxBdecreased sorting to prestalk region
DBS0236732paxB-/ [pspA]: paxB: GFPpaxBdecreased sorting to prestalk region
DBS0236734pde4-pde4decreased culmination | delayed slug formation | delayed culmination
DBS0236736pdeD-pdeDdecreased cAMP-induced Ca2+ influx | delayed cAMP-induced Ca2+ influx | decreased Ca2+-induced Ca2+ influx
UK7pdsA-pdsAdecreased 3',5'-cyclic-AMP phosphodiesterase activity | abolished aggregation
DBS0236749pefB-/ noxC-noxCabolished sporulation | aberrant development
DBS0236749pefB-/ noxC-pefBabolished sporulation | aberrant development
DBS0236752phdA-phdAdecreased basal F-actin level | decreased aggregate size | decreased chemotaxis rate | decreased fruiting body size
DBS0304872phg1A-/ phg1b-phg1aincreased secretion of lysosomal enzyme | decreased cell-substrate adhesion | decreased phagocytosis | decreased growth rate | development arrests at tipped mound stage | abolished culmination
DBS0304872phg1A-/ phg1b-phg1bincreased secretion of lysosomal enzyme | decreased cell-substrate adhesion | decreased phagocytosis | decreased growth rate | development arrests at tipped mound stage | abolished culmination
DBS0236755phg1a-phg1aincreased secretion of lysosomal enzyme | decreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | abolished resistance to pathogenic bacteria | decreased growth rate | development arrests at slug stage
DBS0304866phg1b-phg1bincreased secretion of lysosomal enzyme | decreased phagocytosis | decreased growth rate | abolished culmination
DBS0236758phg2-phg2decreased cell-substrate adhesion | decreased phagocytosis | aberrant cytokinesis | aberrant F-actin organization | decreased cell motility | aberrant response to nutrients | aberrant cell morphology | precocious development | precocious gene expression
DBS0236762phlp1-phlp1decreased growth rate in suspension | decreased cAMP-induced cGMP pulse | aberrant regulation of protein modification | abolished chemotaxis | abolished aggregation | decreased growth rate on bacterial plates | decreased cAMP-induced cAMP pulse | aberrant protein localization
HW288phyA-phyAabolished sporulation | decreased peptidyl-proline hydroxylation | abolished stalk formation | abolished culmination
DBS0266770phyA-/ [ecmA]: phyA(R276A): mycphyAabolished peptidyl-proline hydroxylation | abolished culmination
DBS0236767pia-piaAaberrant activation of adenylate cyclase activity
DBS0236769piaA(G917D)/ [act15]: piaApiaAdelayed aggregation
DBS0236771piaA-piaAabolished aggregation | decreased myosin II assembly
HSB1piaA-piaAdecreased activation of adenylate cyclase | abolished aggregation
DBS0236766pikA-/ pikB-pikAaberrant negative chemotaxis | decreased cell motility | decreased chemotaxis to folate | decreased cAMP-induced cAMP pulse
DBS0236766pikA-/ pikB-pikBaberrant negative chemotaxis | decreased cell motility | decreased chemotaxis to folate | decreased cAMP-induced cAMP pulse
DBS0236773pikA-/ pikB-pikAabolished CRAC localization to the plasma membrane | increased intracellular cAMP level | aberrant adaptation of adenylate cyclase | abolished SDF production | delayed aggregation | abolished growth in suspension | multiple tips | abolished streaming | decreased cAMP-induced cAMP pulse
DBS0236773pikA-/ pikB-pikBabolished CRAC localization to the plasma membrane | increased intracellular cAMP level | aberrant adaptation of adenylate cyclase | abolished SDF production | delayed aggregation | abolished growth in suspension | multiple tips | abolished streaming | decreased cAMP-induced cAMP pulse
HM1200pikA-/ pikB-/ pikC-/ pikF-/ pikG-pikAaberrant aggregation | decreased growth rate in bacterial suspension | decreased protein tyrosine phosphorylation | decreased cell motility
HM1200pikA-/ pikB-/ pikC-/ pikF-/ pikG-pikBaberrant aggregation | decreased growth rate in bacterial suspension | decreased protein tyrosine phosphorylation | decreased cell motility
HM1200pikA-/ pikB-/ pikC-/ pikF-/ pikG-pikCaberrant aggregation | decreased growth rate in bacterial suspension | decreased protein tyrosine phosphorylation | decreased cell motility
HM1200pikA-/ pikB-/ pikC-/ pikF-/ pikG-pikFaberrant aggregation | decreased growth rate in bacterial suspension | decreased protein tyrosine phosphorylation | decreased cell motility
HM1200pikA-/ pikB-/ pikC-/ pikF-/ pikG-pikGaberrant aggregation | decreased growth rate in bacterial suspension | decreased protein tyrosine phosphorylation | decreased cell motility
HM1295pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pten-pikAaberrant aggregation | decreased growth rate | decreased cell motility
HM1295pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pten-pikBaberrant aggregation | decreased growth rate | decreased cell motility
HM1295pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pten-pikCaberrant aggregation | decreased growth rate | decreased cell motility
HM1295pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pten-pikFaberrant aggregation | decreased growth rate | decreased cell motility
HM1295pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pten-pikGaberrant aggregation | decreased growth rate | decreased cell motility
HM1295pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pten-ptenaberrant aggregation | decreased growth rate | decreased cell motility
DBS0238073pikA-/ pikB-/ plaA-pikAdecreased chemoattractant-mediated F-actin polymerization | abolished chemotaxis | delayed aggregation
DBS0238073pikA-/ pikB-/ plaA-pikBdecreased chemoattractant-mediated F-actin polymerization | abolished chemotaxis | delayed aggregation
DBS0238073pikA-/ pikB-/ plaA-plaAdecreased chemoattractant-mediated F-actin polymerization | abolished chemotaxis | delayed aggregation
DBS0236777pikD1pikDabolished slug migration | delayed aggregation | decreased number of spores | decreased aggregate size | aberrant fruiting body morphology
DBS0236782pkaC-/ gdt1-gdt1increased gene expression | abolished aggregation
DBS0236782pkaC-/ gdt1-pkaCincreased gene expression | abolished aggregation
HTY217pkaR(A31T)pkaRprecocious development
DBS0235411pkaR-pkaRaberrant response to lithium | aberrant response to valproic acid | decreased fruiting body size
DBS0236785pkbA-/ pkgB-pkbAabolished growth | decreased chemotaxis rate | abolished aggregation
DBS0236785pkbA-/ pkgB-pkgBabolished growth | decreased chemotaxis rate | abolished aggregation
DBS0236786pkgB-pkgBabolished SDF production | development arrests at mound stage
DBS0304638pkgB-pkgBdecreased cell-substrate adhesion | development arrests at mound stage | decreased chemotaxis rate | increased cell motility
DBS0236789pkgB-/ [act15]: pkgB(K182M)pkgBdevelopment arrests at mound stage
DBS0238068plaA-plaAabolished aggregation
DBS0238067plaA-plaAabolished aggregation
DG1067plbG-plbGdecreased stalk width | decreased stalk length
HAD236plc-plcdecreased activation of protein kinase B | decreased CRAC localization to the plasma membrane | aberrant chemotaxis to cAMP | abolished aggregation | decreased localization of protein to the cytoplasm
DBS0236796pldB-pldBprecocious aggregation
DBS0236797pldB-/ [act15]: pldB: GFPpldBabolished aggregation
DBS0236799plip-plipdelayed aggregation
DBS0236820ponA-ponAprecocious aggregation | decreased lateral pseudopod traction | decreased actin nucleation on plasma membranes | aberrant development
DBS0236821ponA-ponAprecocious aggregation | decreased lateral pseudopod traction | decreased actin nucleation on plasma membranes | aberrant development
DG1057potA-potAaberrant fruiting body morphology
DBS0236824ppk1-ppk1decreased phagocytosis | decreased fruiting body size | decreased growth rate on bacterial plates | delayed culmination | decreased sporulation
DBS0238099ppp4C-ppp4cdevelopment arrests at mound stage | delayed development
DBS0238110ppp4C-/ [act15]: smkAppp4cdevelopment arrests at mound stage | delayed development
DBS0238110ppp4C-/ [act15]: smkAsmkAdevelopment arrests at mound stage | delayed development
HOK2psiA-psiAabolished prespore cell division
DBS0236828pslA-pslAabolished gene expression | abolished sporulation | abolished stalk cell differentiation in vitro | decreased sorus size | increased aggregate size | increased stalk length | mislocalized gene expression
DBS0236829psmC1-psmC1curly fingers | increased resistance to spectinomycin | abolished slug migration | increased cell size
DBS0302352psrA-psrAdecreased culmination | increased protein phosphorylation | delayed development | delayed gene expression | increased protein kinase activation
DBS0302357psrA-/ [act15]: gskA(K84M/ K85M)gskAdecreased culmination | decreased gene expression | delayed development
DBS0302357psrA-/ [act15]: gskA(K84M/ K85M)psrAdecreased culmination | decreased gene expression | delayed development
DBS0236830pten-ptenabolished CRAC localization to the plasma membrane | decreased F-actin polymerization | increased pseudopod formation | decreased growth rate | increased F-actin polymerization | increased lateral pseudopod formation | decreased cell motility | increased CRAC localization to the plasma membrane | decreased chemotaxis to cAMP | abolished aggregation | decreased lateral pseudopod suppression
DBS0236832ptpA1-ptpA1-1decreased prespore cell differentiation | precocious development | increased prestalk O cell differentiation
DBS0236833ptpB-ptpBincreased slug size
DBS0236835pufA-pufAprecocious development | aberrant fruiting body morphology
DBS0304391pyk3-pyk3increased gene expression | decreased gene expression | increased prespore cell differentiation | delayed culmination
DBS0236836pykA-pykAdecreased growth rate | abolished aggregation
DBS0236839qkgA-qkgA-1increased aggregate size | delayed aggregation | increased growth rate
DBS0236839qkgA-qkgA-2increased aggregate size | delayed aggregation | increased growth rate
DBS0236841racB-racBdecreased chemoattractant-mediated F-actin polymerization | delayed aggregation | decreased basal F-actin level | decreased chemotaxis rate | aberrant fruiting body morphology | decreased myosin II assembly
DBS0236843racF2-racF2increased aggregate size | increased cell-cell adhesion | decreased sexual fusion
DBS0236853rasC-/ AX2rasCdecreased activation of protein kinase B | decreased cell motility | abolished aggregation
DBS0236854rasC-/ JH10rasCdecreased activation of protein kinase B | aberrant gene expression | abolished aggregation | abolished chemotaxis to cAMP
DBS0236855rasC-/ dmpA-dmpAabolished streaming
DBS0236855rasC-/ dmpA-rasCabolished streaming
DBS0236856rasC-/ pikD1pikDdecreased activation of protein kinase B | increased chemotaxis to cAMP | aberrant gene expression | abolished aggregation | increased cell polarity | aberrant fruiting body morphology
DBS0236856rasC-/ pikD1rasCdecreased activation of protein kinase B | increased chemotaxis to cAMP | aberrant gene expression | abolished aggregation | increased cell polarity | aberrant fruiting body morphology
DBS0236857rasC-/ rasD-rasCabolished aggregation
DBS0236857rasC-/ rasD-rasDabolished aggregation
DBS0236858rasC-/ rasG-rasCdecreased gene expression | abolished growth | abolished protein kinase B activation | decreased growth rate | decreased activation of adenylate cyclase | decreased cell motility | abolished aggregation | delayed gene expression | abolished chemotaxis to cAMP | abolished GTP-gamma-S-stimulated guanylyl cyclase activity
DBS0236858rasC-/ rasG-rasGdecreased gene expression | abolished growth | abolished protein kinase B activation | decreased growth rate | decreased activation of adenylate cyclase | decreased cell motility | abolished aggregation | delayed gene expression | abolished chemotaxis to cAMP | abolished GTP-gamma-S-stimulated guanylyl cyclase activity
DBS0266697rasC-/ rasG-/ [act15]: carAcarA-1abolished activation of Rap GTPase activity | abolished growth | decreased growth rate | abolished protein kinase B activation | decreased activation of adenylate cyclase | abolished cAMP-induced cGMP pulse | abolished chemotaxis to cAMP
DBS0266697rasC-/ rasG-/ [act15]: carAcarA-2abolished activation of Rap GTPase activity | abolished growth | decreased growth rate | abolished protein kinase B activation | decreased activation of adenylate cyclase | abolished cAMP-induced cGMP pulse | abolished chemotaxis to cAMP
DBS0266697rasC-/ rasG-/ [act15]: carArasCabolished activation of Rap GTPase activity | abolished growth | decreased growth rate | abolished protein kinase B activation | decreased activation of adenylate cyclase | abolished cAMP-induced cGMP pulse | abolished chemotaxis to cAMP
DBS0266697rasC-/ rasG-/ [act15]: carArasGabolished activation of Rap GTPase activity | abolished growth | decreased growth rate | abolished protein kinase B activation | decreased activation of adenylate cyclase | abolished cAMP-induced cGMP pulse | abolished chemotaxis to cAMP
DBS0236859rasD(G12T)rasDdevelopment arrests at mound stage | development arrests at tipped mound stage
DBS0236862rasG-/ AX2rasGdecreased activation of protein kinase B | decreased cAMP-induced cGMP pulse | decreased gene expression | delayed aggregation | delayed gene expression
DBS0236863rasG-/ JH10rasGdecreased activation of protein kinase B | decreased cAMP-induced cGMP pulse | decreased gene expression | abolished activation of Rap GTPase activity | delayed aggregation | delayed gene expression
DBS0236877rblA-rblAincreased sorting to prestalk region | precocious development | increased prestalk cell differentiation in response to DIF-1 | decreased cell size
DBS0236878rbrA-rbrAincreased gene expression | decreased gene expression | development arrests at slug stage | mislocalized gene expression | decreased sorting to prestalk region | decreased phototaxis | decreased sporulation
DBS0236880rckA-rckAdelayed slug formation | increased aggregate size | precocious aggregation | delayed gene expression | increased chemotaxis rate
DBS0236885rckA-/ [act15]: myc: rckArckAdelayed development | decreased chemotaxis rate
DBS0236881rckA-/ [act15]: myc: rckA(C551A)rckAdelayed slug formation | decreased chemotaxis rate
DBS0236883rckA-/ [act15]: myc: rckA(E510G/ N511A)rckAdelayed slug formation | decreased chemotaxis rate
DBS0236884rckA-/ [act15]: myc: rckA(K867A)rckAdevelopment arrests at mound stage | decreased chemotaxis rate
FR17rdeA-rdeAprecocious aggregation | decreased aggregate size | precocious development | precocious gene expression | aberrant fruiting body morphology
FR17rdeA-rdeAprecocious aggregation | decreased aggregate size | precocious development | precocious gene expression | aberrant fruiting body morphology
DBS0266664redA-redAdevelopment arrests at mound stage | aberrant mound color
DG1047redA-redAdevelopment arrests at mound stage | aberrant mound color
DBS0236889regA-regAincreased resistance to cisplatin | aberrant chemotaxis to cAMP | aberrant fruiting body morphology
HR45regA-regAaberrant fruiting body morphology
DBS0235706regA-/ [act15]: dhkK(D1125N)dhkKprecocious development | aberrant fruiting body morphology
DBS0235706regA-/ [act15]: dhkK(D1125N)regAprecocious development | aberrant fruiting body morphology
DBS0235708regA-/ [act15]: dhkK(H825Q)dhkKprecocious development | aberrant fruiting body morphology
DBS0235708regA-/ [act15]: dhkK(H825Q)regAprecocious development | aberrant fruiting body morphology
DBS0236891regA-/ tagB-regAdecreased sporulation
DBS0236891regA-/ tagB-tagBdecreased sporulation
DBS0236892regA-/ tagC-regAdecreased sporulation
DBS0236892regA-/ tagC-tagCdecreased sporulation
DBS0236893rgaA-rgaAaberrant cytokinesis | abolished sorting to prestalk region | abolished stalk cell differentiation | abolished culmination | decreased sporulation
DBS0238225rpkA-rpkAdevelopment arrests at loose aggregate stage | aberrant response to conditioned medium factor | decreased cell polarity | decreased cell motility | abolished aggregation
DBS0236875rtoA-rtoAdecreased rate of endocytosis | decreased infection rate by Legionella pneumophila | increased prestalk cell differentiation | delayed culmination
DBS0236911rtoA-rtoAdelayed development
DBS0236914rzpA-rzpAaberrant aggregation | decreased slug migration | increased aggregate size | increased gene expression | decreased gene expression | delayed development
DBS0236915rzpA-OErzpAincreased gene expression | decreased gene expression | delayed culmination
DBS0236924scrA-scrAdecreased basal F-actin level | increased lateral pseudopod formation | multiple tips | decreased fruiting body size | precocious development | decreased cell size
DBS0236928set1-set1precocious aggregation | abolished histone H3-K4 methylation | precocious gene expression
DG1008sfbA-sfbAdecreased fruiting body size
SA555sglA-sglAaberrant cytoskeleton organisation | increased stalk width | increased resistance to cisplatin | increased aggregate size | decreased gene expression | abolished slug migration | decreased cell motility | decreased chemotaxis rate | decreased fruiting body size | decreased lateral pseudopod suppression | decreased sporulation
SA554sglA-sglAdelayed aggregation | decreased aggregate size
DBS0236934shkA-shkAaberrant aggregation | decreased cell polarity | aberrant F-actin organization | decreased phagocytosis | aberrant cytokinesis | decreased chemotaxis rate | decreased fruiting body size
DBS0236938smkA-smkAaberrant cytokinesis | delayed development | decreased chemotaxis rate | decreased myosin II assembly
HDB7YAsmlA-smlAdecreased secretion of lysosomal enzyme | decreased cell-cell adhesion | decreased cAMP-induced cGMP pulse | decreased GTP-gamma-S-stimulated guanylyl cyclase activity | increased cAMP-induced cAMP pulse | increased resistance to cisplatin | decreased protein level | increased basal F-actin level | increased myosin II assembly | increased protein level | increased extracellular counting factor component(s) level | increased cell motility | decreased fruiting body size | increased intracellular counting factor component(s) level
DBS0302657smlA-/ cnrN-cnrNdecreased fruiting body size
DBS0302657smlA-/ cnrN-smlAdecreased fruiting body size
DBS0304496smlA-/ sslA1(CR11)smlAincreased fruiting body size
DBS0304496smlA-/ sslA1(CR11)sslA1increased fruiting body size
DBS0302524sodC-sodCdecreased positive regulation of Ras GTPase activity | decreased chemoattractant-mediated F-actin polymerization | aberrant aggregation | increased localization of protein to the plasma membrane | aberrant localization of protein to the plasma membrane | increased basal F-actin level | decreased chemotaxis rate | aberrant cell morphology
HL351spiA-spiAdecreased spore viability
DBS0236943spkA-1-/ spkA-2-spkA-1decreased cell polarity | decreased cell-substrate adhesion | aberrant cytokinesis | decreased chemotaxis rate | decreased aggregate size | aberrant cell morphology | decreased fruiting body size
DBS0236943spkA-1-/ spkA-2-spkA-2decreased cell polarity | decreased cell-substrate adhesion | aberrant cytokinesis | decreased chemotaxis rate | decreased aggregate size | aberrant cell morphology | decreased fruiting body size
DBS0236944spkA-1-/ spkA-2-/ [act15]: spkA: FLAGspkA-1aberrant aggregation | decreased cell polarity | aberrant F-actin organization | decreased chemotaxis rate
DBS0236944spkA-1-/ spkA-2-/ [act15]: spkA: FLAGspkA-2aberrant aggregation | decreased cell polarity | aberrant F-actin organization | decreased chemotaxis rate
DBS0236945splA-splAaberrant spore morphology | increased sorus size | translucent sorus | spores inviable | decreased stalk length
DBS0236947spnA-spnAabolished prespore cell differentiation | development arrests at mound stage | abolished prestalk cell differentiation | aberrant development
DBS0236948spnA-/ arkA-arkAdecreased gene expression | increased sorus size | decreased stalk length | delayed gene expression
DBS0236948spnA-/ arkA-spnAdecreased gene expression | increased sorus size | decreased stalk length | delayed gene expression
DBS0236949sr-srdecreased intracellular pteridine level | decreased spore viability | decreased cytochrome C oxidase activity | decreased growth rate
DBS0236950srfA(1-8): lacZsrfAdecreased slug migration | aberrant fruiting body morphology | delayed culmination
DBS0236951srfA-srfAaberrant spore morphology | aberrant spore coat morphology | decreased spore viability | decreased gene expression
DBS0266691srfB-srfBaberrant cAMP signaling | precocious aggregation | decreased growth rate | increased pinocytosis | aberrant cytokinesis | increased lateral pseudopod formation | abolished streaming | precocious gene expression
DBS0304409srsA-srsAdecreased gene expression | increased gene expression | increased aggregate size | delayed aggregation
DBS0304497sslA1-/ sslA1(CR11)sslA1decreased cAMP-induced cGMP pulse | increased fruiting body size | decreased cAMP-induced cAMP pulse
DBS0236952stkA-stkAincreased gene expression | decreased gene expression | increased prestalk cell differentiation | aberrant fruiting body morphology | delayed gene expression
HM1154stlB-stlBabolished prestalk B cell differentation | abolished DIF production | decreased prestalk O cell differentiation | abolished lower cup formation | abolished outer basal disc formation | decreased prestalk cell differentiation | aberrant fruiting body morphology
DBS0304547svkA-svkAdelayed cell separation during cytokinesis | aberrant cytokinesis | aberrant fruiting body morphology
DBS0236958t96AregAdecreased spore germination | precocious sporulation
AK1200tagA-tagAabolished SDF production | aberrant fruiting body morphology
AK859tagA-tagAdecreased spore viability | abolished SDF production | multiple tips in mound | increased prestalk A cell differentiation
AK1201tagA-/ [ecmA]: GFPtagAabolished sorting to prestalk region
AK228tagB-tagBdevelopment arrests at mound stage | abolished DIF production | aberrant prestalk A cell differentiation
DBS0236974tagB-/ psmA1-psmA1abolished sporulation
DBS0236974tagB-/ psmA1-tagBabolished sporulation
DBS0236975tagC-tagCdevelopment arrests at mound stage | spores inviable
DBS0304581talA-/ talB-talAdevelopment arrests at loose aggregate stage | abolished cell-substrate adhesion | aberrant cytokinesis | abolished cell motility
DBS0304581talA-/ talB-talBdevelopment arrests at loose aggregate stage | abolished cell-substrate adhesion | aberrant cytokinesis | abolished cell motility
HKT104talB-talBdecreased slug migration | decreased cell motility | development arrests at tipped mound stage | increased protein level
DBS0302472talB-talBabolished autophagic vacuole formation | abolished autophagic cell death
DBS0304586talB-/ [act15]: talA: GFPtalAaberrant fruiting body morphology
DBS0304586talB-/ [act15]: talA: GFPtalBaberrant fruiting body morphology
DBS0304820tgrB1-tgrB1development arrests at loose aggregate stage | delayed sporulation | decreased sporulation
DBS0304821tgrC1-tgrC1abolished sporulation | development arrests at loose aggregate stage in the presence of EGTA
AK244tipA-tipAincreased aggregate size | decreased gene expression | development arrests at mound stage | multiple tips
JS64tipA-/ tipB-/ [act15]: lacZtipAincreased aggregate size | development arrests at mound stage | multiple tips in mound
JS64tipA-/ tipB-/ [act15]: lacZtipBincreased aggregate size | development arrests at mound stage | multiple tips in mound
JS98tipA-/ tipC-/ [ecmA]: lacZtipAdevelopment arrests at loose aggregate stage
JS98tipA-/ tipC-/ [ecmA]: lacZtipCdevelopment arrests at loose aggregate stage
JS128tipA-/ tipD-/ [ecmA]: lacZtipAdevelopment arrests at loose aggregate stage
JS128tipA-/ tipD-/ [ecmA]: lacZtipDdevelopment arrests at loose aggregate stage
JS56tipB-tipBincreased aggregate size | development arrests at mound stage | multiple tips | multiple tips in mound
JS99tipB-/ tipC-/ [ecmA]: lacZtipBdevelopment arrests at tipped mound stage | multiple tips in mound
JS99tipB-/ tipC-/ [ecmA]: lacZtipCdevelopment arrests at tipped mound stage | multiple tips in mound
JS129tipB-/ tipD-/ [ecmA]: lacZtipBdevelopment arrests at tipped mound stage | multiple tips in mound
JS129tipB-/ tipD-/ [ecmA]: lacZtipDdevelopment arrests at tipped mound stage | multiple tips in mound
JS55tipC-tipCincreased aggregate size | development arrests at mound stage | multiple tips
JS130tipC-/ tipD-/ [ecmA]: lacZtipCdevelopment arrests at loose aggregate stage
JS130tipC-/ tipD-/ [ecmA]: lacZtipDdevelopment arrests at loose aggregate stage
JS93tipD-tipDincreased aggregate size | development arrests at mound stage | multiple tips
DBS0237017torA-torAdelayed aggregation | decreased growth rate | decreased cell motility | decreased chemotaxis rate
DBS0237924triA-triAdecreased cell-cell adhesion | aberrant streaming | increased stalk width | aberrant upper cup formation | decreased spore viability | aberrant culminant morphology | decreased spore size | decreased cell fate determination | increased number of aggregates | decreased cell fate commitment
DBS0237996triA-triAaberrant culminant morphology
DBS0237997triA-triAaberrant culminant morphology
DBS0237998triA-/ [act15]: GFPtriAaberrant culminant morphology
DBS0237999triA-/ [ecmAO]: lacZ: [ecmAO]: gustriAincreased prestalk O cell differentiation
DBS0238001triA-/ [psA]: lacZ: [psA]: gustriAincreased prespore cell differentiation
DBS0237022tsg101-tsg101decreased fruiting body size
DBS0302370tsuA-tsuAincreased period of cAMP wave formation | aberrant chemotaxis to folate | aberrant chemotaxis to cAMP | delayed aggregation | decreased aggregate size | abolished cell polarity | decreased fruiting body size
DBS0302383tsuA-/ [unk]: tsuA(1-1774): YFPtsuAabolished localization of protein to the microtubule organizing center | decreased aggregate size | abolished localization of protein to microtubules | decreased fruiting body size
DBS0302385tsuA-/ [unk]: tsuA(1-260): YFPtsuAabolished localization of protein to the microtubule organizing center | abolished localization of protein to microtubules | decreased aggregate size | decreased fruiting body size
DBS0302384tsuA-/ [unk]: tsuA(1774-2247): YFPtsuAabolished localization of protein to the microtubule organizing center | abolished localization of protein to microtubules | decreased aggregate size | decreased fruiting body size
DBS0302382tsuA-/ [unk]: tsuA(K34R): YFPtsuAdecreased aggregate size | decreased fruiting body size
DBS0237024ubcB-ubcBdevelopment arrests at mound stage | multiple tips
DBS0237025ubpA-ubpAdecreased gene expression | decreased chemotaxis rate | abolished aggregation | decreased cAMP-induced cAMP pulse
DBS0237026ubpB-ubpBaberrant sorus morphology | increased gene expression | decreased gene expression | precocious development
DBS0266763ugpB-/ DH1ugpBdecreased stalk length
DBS0236058vmp1-vmp1aberrant aggregation | decreased exocytosis | decreased pinocytosis | aberrant response to hypo-osmotic stress | decreased gene expression | decreased growth rate
DG1118vps46-vps46increased sorus size
DBS0237046vwkA-vwkAdecreased growth rate in suspension | increased myosin II assembly | aberrant cytokinesis | delayed development | increased protein level | aberrant fruiting body morphology
DBS0237048warA-warAdevelopment arrests at slug stage | increased basal disc size | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0237049warA-warAdevelopment arrests at slug stage | increased basal disc size | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0237050warA-/ hbx2-hbx2increased basal disc size | development arrests at mound stage | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0237050warA-/ hbx2-warAincreased basal disc size | development arrests at mound stage | decreased prespore cell differentiation | increased prestalk O cell differentiation
DBS0237051wasA1-wasAaberrant F-actin organization | decreased cell motility | delayed development
DBS0237052wasA1-/ [tet]: YFP: wasA2wasAdecreased F-actin polymerization | abolished chemotaxis | aberrant F-actin organization | abolished aggregation
DG1053wimA-wimAaberrant fruiting body morphology
DG1064wimA-wimAaberrant fruiting body morphology
AK235yakA-yakAabolished aggregation
AK800yakA-yakAabolished aggregation
DG1014yelA-yelAdecreased spore viability | precocious sporulation | development arrests at mound stage | aberrant mound color
DBS0349797zak2-zak2decreased gene expression | decreased protein kinase activation | decreased sporulation | aberrant fruiting body morphology
ARK100-110zakA-zakAdecreased glycogen synthase kinase 3 activity | increased gene expression | decreased gene expression | abolished streaming | decreased chemotaxis to cAMP | delayed culmination | aberrant fruiting body morphology | decreased sporulation
DBS0238142zakA-zakAdevelopment arrests at tipped mound stage
DG1050zipA-zipAdecreased fruiting body size

Last updated January 28, 2012

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