Phenotypes for Dictyostelium mutants

View other mutant types: All mutant strains - Null - Overexpression - Multiple - Other - Developmental

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Systematic Name	Strain Descriptor	Associated gene(s)	Phenotypes
DBS0266719	Dd5P4-/ [act15]: Dd5P4: GFP	Dd5P4	wild type
DBS0266695	Dd5P4-/ [act15]: GAP5P4	Dd5P4	decreased growth rate | multiple tips in mound
DBS0266720	Dd5P4-/ [act15]: Hs-OCRL	Dd5P4	decreased phagocytosis
DBS0266721	Dd5P4-/ [act15]: Hs-OCRL(D422A)	Dd5P4	decreased phagocytosis
DBS0266694	Dd5P4-/ [act15]: cat5P4	Dd5P4	decreased growth rate | multiple tips in mound
CW0391	FLAG-VwkA	vwkA	decreased growth rate in suspension | increased myosin II assembly | aberrant cytokinesis | development arrests at mound stage | increased protein level
DBS0236358	HR42	fbxA	abolished culmination | decreased sporulation
DBS0237044	VatMpr/ [act15]: vatM	vatM	wild type
DBS0237042	VatMpr/ [act15]: vatM: GFP	vatM	decreased growth rate
DBS0238036	[AS]proA/ proB-/ [act15]: proA	proA | proB	wild type
DBS0238037	[AS]proA/ proB-/ [act15]: proB	proA | proB	wild type
DBS0238035	[AS]proA/ proB-/ [unk]: FLAG: proC	proA | proB | proC	wild type
DBS0237274	[OE]: chlim	ChLim	increased basal F-actin level | decreased phagocytosis | decreased growth rate
DBS0302602	[OE]: disgorgin(Delta-Fbox)/ disgorgin-	DDB_G0280955	wild type
DBS0302601	[OE]: disgorgin(Q551A)/ disgorgin-	DDB_G0280955	aberrant contractile vacuole organization and biogenesis
DBS0302600	[OE]: disgorgin(R515A)/ disgorgin-	DDB_G0280955	aberrant contractile vacuole organization and biogenesis
DBS0302599	[OE]: disgorgin/ disgorgin-	DDB_G0280955	wild type
DBS0302610	[OE]: disgorgin/ phgA-	DDB_G0280955 | phgA	aberrant contractile vacuole organization and biogenesis
JH258	[OE]: gpaE	gpaE	precocious tip formation | precocious gene expression
DBS0348921	[OE]: ipkA1	ipkA1	aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression
DBS0348922	[OE]: itpk1	itpk1	aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression
DBS0302611	[OE]: phgA/ disgorgin-	DDB_G0280955 | phgA	aberrant contractile vacuole organization and biogenesis
DBS0302681	[OE]: sgcA(878-2843): GFP/ sgcA-	gcA | sgcA	decreased chemotaxis rate
DBS0302682	[OE]: sgcA(N1106A): GFP/ gca-/ sgcA-	gcA | sgcA	aberrant streaming | increased lateral pseudopod formation | decreased chemotaxis rate
DBS0266621	[OE]mipp1	mipp1	aberrant inositol phosphate metabolic process | aberrant gene expression | increased response to lithium
DBS0349845	[act15]: 7xHis: myoK: Ty1	myoK	aberrant cortical actin cytoskeleton stabilization | aberrant engulfment during phagocytosis | aberrant cell morphology
DBS0266512	[act15]: DDB_G0272656	DDB_G0272656	wild type
DBS0238107	[act15]: FLAG: ppp4C	ppp4c	wild type
DBS0238108	[act15]: FLAG: ppp4C(H113Q)	ppp4c	development arrests at mound stage | delayed development
DBS0304572	[act15]: GFP: abpD(1441-1736)	abpD	abolished localization of a protein to the nuclear envelope
DBS0304571	[act15]: GFP: abpD(1441-1738)	abpD	abolished localization of a protein to the nuclear envelope
DBS0304573	[act15]: GFP: abpD(1441-1738,1737P/ A)	abpD	abolished localization of a protein to the nuclear envelope
DBS0237114	[act15]: GFP: abpE(413-481)	abpE-1 | abpE-2	increased lateral pseudopod formation
DBS0235662	[act15]: GFP: forH(1-425)	forH	aberrant protein localization
DBS0304973	[act15]: GFP: gefQ(173-651,818-1298)	gefQ	increased Ras guanyl-nucleotide exchange factor activity
DBS0304971	[act15]: GFP: gefQ(683-833)	gefQ	decreased Ras guanyl-nucleotide exchange factor activity
DBS0304972	[act15]: GFP: gefQ(910-1298)	gefQ	aberrant cytokinesis | aberrant phototaxis
DBS0236070	[act15]: GFP: hcpA	hcpA	decreased growth rate in suspension | aberrant anaphase
DBS0237117	[act15]: GFP: krsA	krsA	decreased slug migration
DBS0237118	[act15]: GFP: limE	limE	aberrant cytokinesis
DBS0237122	[act15]: GFP: pats1(2087-2351)	pats1	aberrant cytokinesis
DBS0237123	[act15]: GFP: phg2(1-245)	phg2	decreased phagocytosis
DBS0237702	[act15]: GFP: rac1A	rac1A	increased filopodium formation | increased membrane ruffling
DBS0237703	[act15]: GFP: rac1B	rac1B	increased filopodium formation | increased membrane ruffling
DBS0237704	[act15]: GFP: rac1C	rac1C	increased filopodium formation | increased membrane ruffling
DBS0237125	[act15]: GFP: racG(1-168): racH(164-200)	racG | racH	increased filopodium formation | decreased chemoattractant-mediated F-actin polymerization | decreased phagocytosis
DBS0237128	[act15]: GFP: racH(1-163): racG(167-201)	racG | racH	decreased chemoattractant-mediated F-actin polymerization
DBS0237130	[act15]: GFP: racH(M13V)	racH	increased F-actin polymerization | aberrant cytokinesis | aberrant cell morphology
DBS0237132	[act15]: GFP: racH(T18N)	racH	aberrant cytokinesis | aberrant cell morphology
DBS0237133	[act15]: GFP: racH: gemA(630-658)	gemA | racH	delayed cytokinesis
DBS0238392	[act15]: GFP: rapA	rapA	increased cell-substrate adhesion
DBS0238393	[act15]: GFP: rapA(G12V)	rapA	increased cell-substrate adhesion
DBS0238394	[act15]: GFP: rapA(S17N)	rapA	decreased cell-substrate adhesion
DBS0237134	[act15]: GFP: sbds	sbds	wild type
DBS0237135	[act15]: GFP: sbds	sbds	wild type
DBS0304563	[act15]: GFP: sun1(283-905)	sun1	increased number of centrosomes | increased cell size | aberrant nucleus morphology | aberrant perinuclear space | aberrant centrosome localization | aberrant sister chromosome segregation | decreased localization of a protein to the nuclear envelope
DBS0238111	[act15]: HA: smkA	smkA	decreased cell polarity | delayed development | decreased fruiting body size | decreased chemotaxis to cAMP
DBS0237817	[act15]: YFP: wipA	wipA	increased filopodium formation | increased F-actin polymerization at the leading edge
DBS0237819	[act15]: YFP: wipA(K36A)	wipA	increased filopodium formation | increased F-actin polymerization at the leading edge
DBS0237821	[act15]: YFP: wipA(K93A/ S95A)	wipA	increased filopodium formation | increased F-actin polymerization at the leading edge
DBS0304574	[act15]: abpD	abpD	abolished localization of a protein to the nuclear envelope
DBS0237096	[act15]: abpE	abpE-1 | abpE-2	aberrant aggregation | increased lateral pseudopod formation | decreased cell motility | delayed development | decreased fruiting body size
DBS0238086	[act15]: atg1	atg1	wild type
DBS0238091	[act15]: atg1(1-628)	atg1	wild type
DBS0238088	[act15]: atg1(K36A)	atg1	abolished macroautophagy | increased number of autophagosomes | aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238090	[act15]: atg1(K36A/ 1-628)	atg1	wild type
DBS0252737	[act15]: carA(I104A)	carA-1 | carA-2	decreased cAMP binding
DBS0252732	[act15]: carA(I104C)	carA-1 | carA-2	decreased MAP kinase activation
DBS0252740	[act15]: carA(I104D)	carA-1 | carA-2	increased cAMP binding | delayed aggregation | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0252744	[act15]: carA(I104E)	carA-1 | carA-2	increased cAMP binding | delayed aggregation | aberrant cAMP wave formation
DBS0252741	[act15]: carA(I104F)	carA-1 | carA-2	increased cAMP binding | decreased MAP kinase activation
DBS0252738	[act15]: carA(I104G)	carA-1 | carA-2	increased cAMP binding | decreased MAP kinase activation
DBS0252747	[act15]: carA(I104H)	carA-1 | carA-2	development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252749	[act15]: carA(I104K)	carA-1 | carA-2	increased cAMP binding | decreased MAP kinase activation | abolished aggregation | abolished cAMP wave formation
DBS0252739	[act15]: carA(I104L)	carA-1 | carA-2	wild type
DBS0252742	[act15]: carA(I104M)	carA-1 | carA-2	increased cAMP binding
DBS0252746	[act15]: carA(I104N)	carA-1 | carA-2	development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252734	[act15]: carA(I104P)	carA-1 | carA-2	decreased MAP kinase activation
DBS0252745	[act15]: carA(I104Q)	carA-1 | carA-2	development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252750	[act15]: carA(I104R)	carA-1 | carA-2	development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | abolished cAMP wave formation
DBS0252743	[act15]: carA(I104S)	carA-1 | carA-2	increased cAMP binding | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0252735	[act15]: carA(I104T)	carA-1 | carA-2	increased cAMP binding | aberrant cAMP wave formation
DBS0252736	[act15]: carA(I104V)	carA-1 | carA-2	wild type
DBS0252733	[act15]: carA(I104W)	carA-1 | carA-2	increased cAMP binding
DBS0252748	[act15]: carA(I104Y)	carA-1 | carA-2	development arrests at loose aggregate stage | increased cAMP binding | decreased MAP kinase activation | aberrant cAMP wave formation
DBS0302445	[act15]: cfaD	cfaD	decreased growth rate | aberrant fruiting body morphology
DBS0302656	[act15]: cnrN/ cnrN-	cnrN	wild type
DBS0302658	[act15]: cnrN/ smlA-	cnrN | smlA	decreased fruiting body size
DBS0237102	[act15]: cofA	cofA	increased actin bundle formation | increased membrane ruffling | increased cell motility
DBS0237104	[act15]: dagA	dagA	wild type
DBS0237106	[act15]: dhkC(394-661)	dhkC	increased slug migration
DBS0235716	[act15]: dhkK	dhkK	precocious aggregation | development arrests at mound stage
DBS0235705	[act15]: dhkK(D1125N)	dhkK	aberrant cAMP signaling during aggregation | delayed development
DBS0235707	[act15]: dhkK(H825Q)	dhkK	precocious development | decreased fruiting body size
DBS0235709	[act15]: dhkK(H825Q/ D1125N)	dhkK	aberrant slug migration | delayed culmination
DBS0237108	[act15]: fbxA: FLAG	fbxA	decreased prespore cell differentiation
DBS0235979	[act15]: fszA: GFP	fszA	increased number of tubular mitochondria
DBS0237136	[act15]: gpaA	gpaA	increased stalk length | aberrant cytokinesis | aberrant fruiting body morphology
DBS0252821	[act15]: hssA	hssA	wild type
DBS0237203	[act15]: mhkB: FLAG	mhkB	aberrant cytokinesis | decreased myosin II assembly
DBS0237162	[act15]: myc-cdk8	cdk8	multiple tips
DBS0266839	[act15]: myc: ptpΔ(3C649S)	ptpC	aberrant localization of protein to the nucleus | increased protein tyrosine phosphorylation
DBS0266837	[act15]: myc: ptpC	ptpC	aberrant signal transduction during aggregation | aberrant response to hyperosmotic stress | aberrant protein localization
DBS0266838	[act15]: myc: ptpC(C649S)	ptpC	aberrant localization of protein to the nucleus | increased protein tyrosine phosphorylation
DBS0238398	[act15]: myc: rapA	rapA	increased cell-substrate adhesion | decreased cell motility | aberrant cell morphology
DBS0238396	[act15]: myc: rapA(G12V)	rapA	delayed aggregation | increased cell-substrate adhesion | decreased cell motility
DBS0238397	[act15]: myc: rapA(S17N)	rapA	decreased cell-substrate adhesion
DBS0237167	[act15]: myc: rckA	rckA	delayed development
DBS0237163	[act15]: myc: rckA(C551A)	rckA	delayed slug formation | decreased chemotaxis rate
DBS0237164	[act15]: myc: rckA(E510G)	rckA	delayed slug formation | decreased chemotaxis rate
DBS0237165	[act15]: myc: rckA(E510G/ N511A)	rckA	delayed slug formation | decreased chemotaxis rate
DBS0237166	[act15]: myc: rckA(K867A)	rckA	delayed slug formation | precocious aggregation | decreased chemotaxis rate
DBS0349847	[act15]: myoK: Myc	myoK	decreased phagocytosis
DBS0237179	[act15]: myr: rckA	rckA	delayed development | decreased chemotaxis rate
DBS0237180	[act15]: nramp1: GFP	nramp1	increased iron ion transport | decreased infection rate by Legionella pneumophila
DBS0237182	[act15]: pakA	pakA	wild type
DBS0237183	[act15]: pakA(K394A)	pakA	development arrests at mound stage | delayed development
DBS0237184	[act15]: pakA[CA]	pakA	abolished aggregation
DBS0237185	[act15]: pakA[G+K]	pakA	wild type
DBS0237188	[act15]: pkaR(1-497)	pkaR	precocious development | decreased intracellular cAMP level | decreased fruiting body size
DBS0235442	[act15]: pldB: GFP	pldB	abolished aggregation
DBS0237192	[act15]: rblA	rblA	increased cell cycle length
DBS0349793	[act15]: sadA(921-S952)	sadA	decreased cell-substrate adhesion
SA604	[act15]: sgkA: FLAG	sgkA	increased resistance to cisplatin | aberrant cytokinesis | increased resistance to carboplatin
DBS0238735	[act15]: snfA(1-379): GFP	snfA	increased stalk width | increased intracellular ATP level | decreased growth rate | increased number of mitochondria | aberrant mitochondrion organization and biogenesis | decreased phototaxis | decreased stalk length
DBS0304457	[act15]: sodA/ gcsA-	gcsA | sodA	wild type
DBS0237194	[act15]: sodA: myc	sodA	decreased gene expression | abolished aggregation
DBS0237195	[act15]: spkA: FLAG	spkA-1 | spkA-2	aberrant aggregation | decreased cell polarity | aberrant F-actin organization | decreased chemotaxis rate
AK1209	[act15]: tagA(1-890)	tagA	multiple tips in mound
DBS0237198	[act15]: torA	torA	abolished growth
DBS0237199	[act15]: trrA	trrA	aberrant aggregation | decreased growth rate | decreased phagocytosis | delayed culmination
DBS0237200	[act15]: vasP	vasP	increased filopodium formation | increased basal F-actin level
DBS0306243	[act6]: GFP: sun1	sun1	increased number of centrosomes | aberrant nucleus morphology | aberrant sister chromosome segregation | aberrant centromere complex assembly | aberrant centrosome organization
DBS0306244	[act6]: GFP: sun1(1-722)	sun1	increased number of centrosomes | aberrant nucleus morphology | aberrant sister chromosome segregation | aberrant centromere complex assembly | aberrant centrosome organization
DBS0238218	[act6]: TAP: GFP: lvsB	lvsB	wild type
DBS0237205	[act6]: dia1	dia1	delayed aggregation
DBS0236905	[act6]: mrps4	mrps4	precocious aggregation
DBS0235444	[act6]: myc: eppA(S250A)	eppA	decreased growth rate | delayed development | decreased intracellular cAMP level
DBS0235445	[act6]: myc: eppA(S325A)	eppA	decreased growth rate
DBS0266836	[act6]: ptpB	ptpB	delayed aggregation | decreased fruiting body size
DBS0304410	[act6]: srsA	srsA	increased aggregate size | decreased gene expression | increased slug size | delayed aggregation | decreased sporulation | aberrant fruiting body morphology
DBS0304460	[act]: alrA/ gcsA-	alrA | gcsA	wild type
DBS0305081	[dscB]: GFP: vamp7A(L35A)	vamp7A	increased localization of protein to the plasma membrane
DBS0304865	[expl7]: expl7: GFP	expl7	aberrant culminant morphology
DBS0237252	[gpaA]: gpaA(G45V)	gpaA	delayed development
DBS0237253	[gpaA]: gpaA(Q206L)	gpaA	increased basal disc size
DBS0236484	[pkaC]: pkaC	pkaC	decreased intracellular cAMP level | precocious development | aberrant fruiting body morphology
DBS0237289	[psmC1]: psmC1	psmC1	aberrant cytokinesis | delayed tip formation | delayed gene expression
DBS0304911	[tre]: paxB	paxB	abolished sporulation | aberrant endocytosis | decreased cell-substrate adhesion | aberrant chemotaxis to folate | development arrests at mound stage | decreased cell motility | increased cell-cell adhesion
DBS0237938	abpC-/ [act15]: GFP: abpC(9-148)	abpC	aberrant phototaxis
DBS0235426	abpC-/ [act15]: abpC	abpC	wild type
DBS0237945	abpC-/ [act15]: abpC(1-348: 449-857): GFP	abpC	aberrant F-actin organization | aberrant phototaxis
DBS0237946	abpC-/ [act15]: abpC(1-556: 644-857): GFP	abpC	aberrant F-actin organization | aberrant phototaxis
DBS0237941	abpC-/ [act15]: abpC(1-739): GFP	abpC	aberrant phototaxis
DBS0349852	abpE-/ [act15]: abpE	abpE-1 | abpE-2	decreased phagocytosis
DBS0237786	acrA-/ [act15]: acgA(1-401)	acgA | acrA	decreased gene expression | decreased prespore cell differentiation | decreased sporulation
DBS0235473	alrA-/ [act15]: alrA	alrA	wild type
DBS0235488	alxA-/ [act15]: FLAG: alxA	alxA	delayed development
DBS0235476	alxA-/ [act15]: alxA(1-596): myc2	alxA	wild type
DBS0235477	alxA-/ [act15]: alxA(1-697): myc2	alxA	wild type
DBS0235478	alxA-/ [act15]: alxA(155-697): myc2	alxA	aberrant fruiting body morphology
DBS0235479	alxA-/ [act15]: alxA(293-697): myc2	alxA	aberrant fruiting body morphology
DBS0235480	alxA-/ [act15]: alxA(460-794): myc2	alxA	aberrant fruiting body morphology
DBS0235481	alxA-/ [act15]: alxA(D310A/ N311A)	alxA	wild type
DBS0235482	alxA-/ [act15]: alxA(Q181E/ Q183)	alxA	wild type
DBS0235483	alxA-/ [act15]: alxA(S700A/ S704A/ S708A)	alxA	wild type
DBS0235484	alxA-/ [act15]: alxA(S700D/ S704D/ S708D)	alxA	wild type
DBS0235485	alxA-/ [act15]: alxA(Y315D)	alxA	wild type
DBS0235486	alxA-/ [act15]: alxA(Y315F)	alxA	wild type
DBS0235487	alxA-/ [act15]: alxA: myc2	alxA	wild type
DBS0235501	amtC-/ [act15]: cudA	amtC | cudA	delayed culmination
DBS0235502	amtC-/ [ecmA]: cudA	amtC | cudA	delayed culmination
DBS0235503	amtC-/ [pspA]: cudA	amtC | cudA	development arrests at slug stage
DBS0305085	apm2-/ [dscB]: GFP: vamp7A	apm2 | vamp7A	increased localization of protein to the plasma membrane
DBS0305083	apm3-/ [dscB]: GFP: vamp7A	apm3 | vamp7A	increased localization of protein to the plasma membrane
DBS0235510	aprA-/ actin15: : aprA	aprA	decreased growth rate | aberrant fruiting body morphology
DBS0238085	atg1-/ [act15]: atg1	atg1	wild type
DBS0238092	atg1-/ [act15]: atg1(1-628)	atg1	aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238087	atg1-/ [act15]: atg1(K36A)	atg1	aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0238089	atg1-/ [act15]: atg1(K36A/ 1-628)	atg1	aberrant cellular response to nitrogen starvation | abolished aggregation
DBS0305978	atg9-/ [act15]: GFP: atg9	atg9	wild type
DBS0305979	atg9-/ [act15]: atg9: GFP	atg9	wild type
DBS0306227	cenB-/ [act15]: RFP: cenB	cenB	wild type
DBS0302446	cfaD-/ [act15]: cfaD	cfaD	wild type
DBS0302455	chcA-/ [act15]: epnA: GFP	chcA | epnA	aberrant localization of a protein to coated pits
DBS0235604	clc-/ [act15]: GFP-clc(146-194)	clc	abolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0235605	clc-/ [act15]: GFP-clc(85-124)	clc	abolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0235607	clc-/ [act15]GFP: clc(1-124)	clc	abolished cytokinesis | wild type | aberrant fruiting body morphology
DBS0238320	cpnA-/ [act15]: GFP: cpnA	cpnA	delayed response to hypo-osmotic stress | decreased culmination | delayed development
DBS0266761	culB-/ [act15]: pkaC	culB | pkaC	abolished gene expression | abolished sporulation | precocious gene expression | abolished aggregation
DBS0349807	detA-/ [act6]: GFP: detA	detA	wild type
DBS0349816	detA-/ [act6]: GFP: detA/ [act6]: 3xHA: culD	culD | detA	increased gene expression
DBS0349817	detA-/ [act6]: GFP: detA/ [act6]: 3xHA: repE	detA | repE	increased gene expression
DBS0349813	detA-/ [cotB]: GFP	detA	decreased prespore cell differentiation
DBS0349811	detA-/ [ecm0]: lacZ	detA	aberrant prestalk O cell differentiation
DBS0349812	detA-/ [ecmA0]: GFP	detA	increased prestalk cell differentiation
DBS0349808	detA-/ [ecmA0]: lacZ	detA	increased prestalk cell differentiation
DBS0349809	detA-/ [ecmA]: lacZ	detA	increased prestalk A cell differentiation
DBS0349810	detA-/ [ecmB]: lacZ	detA	delayed development
DBS0235712	dhkK-/ [act15]: dhkK(D1125N)	dhkK	aberrant fruiting body morphology
DBS0235719	dia1-/ [act6]: trap1	dia1 | trap1	aberrant aggregation | decreased fruiting body size
DBS0235903	dimB-/ [act15]: dimA: GFP	dimA | dimB	abolished localization of protein to the nucleus
DBS0235904	dimB-/ [act15]: dimB: GFP	dimB	wild type
DBS0302607	disgorgin-/ [OE]: lvsA	DDB_G0280955 | lvsA	aberrant contractile vacuole organization and biogenesis
DBS0302606	disgorgin-/ [OE]: lvsD	DDB_G0280955 | lvsD	wild type
DBS0302678	disgorgin-/ [OE]: rab8A	DDB_G0280955 | rab8A	aberrant contractile vacuole organization and biogenesis
DBS0238511	drkC-/ [act15]: drkC(1-497): YFP	drkC	decreased phagocytosis
DBS0238513	drkC-/ [act15]: drkC(K518R): YFP	drkC	decreased phagocytosis
DBS0238237	dstA-/ GFP: dstA(237-707): ORF+	dstA	abolished culmination | decreased stalk length
DBS0252824	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 2C	2C | dstA	aberrant fruiting body morphology
DBS0252823	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 7E	7E | dstA | hssB	wild type
DBS0252826	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0276165	DDB_G0276165 | dstA	aberrant fruiting body morphology
DBS0252825	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0282325	DDB_G0282325 | dstA	aberrant fruiting body morphology
DBS0252816	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssA	dstA | hssA	wild type
DBS0252822	dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssB	dstA | hssB	wild type
DBS0302598	elmoA-/ [act15]: elmoA(1-903/ 959-977): GFP	elmoA	decreased cell motility | increased phagocytosis
DBS0302591	elmoA-/ [act15]: elmoA: GFP	elmoA	wild type
DBS0302457	epnA-/ [act15]: GFP: epnA(253-677)	epnA	abolished localization of protein to the plasma membrane | aberrant spore morphology | abolished localization of protein to coated pits
DBS0302456	epnA-/ [act15]: epnA(1-133): GFP	epnA	aberrant localization of a protein to coated pits
DBS0302474	epnA-/ [act15]: epnA(R65A/ K78A): GFP	epnA	abolished localization of protein to the plasma membrane | aberrant spore morphology | abolished phosphatidylinositol-4,5-bisphosphate binding | abolished localization of protein to coated pits
DBS0302475	epnA-/ [act15]: epnA(T107A): GFP	epnA	aberrant spore morphology
DBS0302454	epnA-/ [act15]: epnA: GFP	epnA	wild type
DBS0235948	eppA-/ [act6]: myc: eppA	eppA	wild type
DBS0304905	forC-/ [act15]: GFP-forC	forC	wild type
DBS0235971	forH-/ [act15]: GFP: forH	forH	increased filopodium formation | decreased cell motility | increased cell-substrate adhesion
DBS0304440	frmA-/ [unk]: GFP	frmA	decreased gene expression | increased cell-cell adhesion | delayed development | aberrant development | abolished phototaxis
DBS0305026	gabT-[pkaC]: pkaC	gabT | pkaC	aberrant protein secretion
DBS0304912	gbpC-/ [act15]: gbpC	gbpC	wild type
DBS0304917	gbpC-/ [act15]: gbpC(1-1698: 2005-2631)	gbpC	decreased chemotaxis to cAMP
DBS0304918	gbpC-/ [act15]: gbpC(311-2631)	gbpC	decreased chemotaxis to cAMP
DBS0304916	gbpC-/ [act15]: gbpC(F1892A)	gbpC	decreased chemotaxis to cAMP
DBS0304915	gbpC-/ [act15]: gbpC(F2082A/ E2084A/ F2564A/ E2566A)	gbpC	decreased chemotaxis to cAMP
DBS0304913	gbpC-/ [act15]: gbpC(K342N)	gbpC	decreased chemotaxis to cAMP
DBS0304914	gbpC-/ [act15]: gbpC(K905W)	gbpC	decreased chemotaxis to cAMP
DBS0235998	gbpD-/ [act15]: gbpD	gbpD	aberrant F-actin organization | increased cell-substrate adhesion | increased lateral pseudopod formation | decreased chemotaxis rate | abolished aggregation
DBS0237190	gdt1-/ [act15]: pkaR(G135E/ G261A)	gdt1 | pkaR	increased gene expression | abolished aggregation
DBS0304985	gefQ-/ [act15]: GFP: gefQ(172-654)	gefQ	abolished Ras guanyl-nucleotide exchange factor activity | decreased phototaxis
DBS0304986	gefQ-/ [act15]: GFP: gefQ(910-1298)	gefQ	decreased phototaxis
DBS0238390	gnt15-/ [act15]: FLAG: gnt15	gnt15	wild type
DBS0238391	gnt15-/ [act15]: FLAG: gnt15	gnt15	wild type
DBS0236092	gpaA-/ [gpaA]: gpaA(G45V)	gpaA	delayed development
DBS0236093	gpaA-/ [gpaA]: gpaA(Q206L)	gpaA	increased basal disc size
DBS0236096	gpaB-/ [act15]: gpaB	gpaB	abolished aggregation
DBS0266942	gpaB-/ [act15]: gpaB	gpaB	delayed aggregation
DBS0266939	gpaB-/ [act15]: gpaB(1-345): gpaD(337-345)	gpaB | gpaD	abolished aggregation
DBS0237137	gpaB-/ [act15]: gpaB(D154V)	gpaB	aberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237138	gpaB-/ [act15]: gpaB(E190G)	gpaB	aberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased cAMP-induced cAMP pulse
DBS0237139	gpaB-/ [act15]: gpaB(I104S)	gpaB	aberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237140	gpaB-/ [act15]: gpaB(L110S)	gpaB	aberrant aggregation | decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | decreased cAMP-induced cAMP pulse
DBS0237141	gpaB-/ [act15]: gpaB(L76P)	gpaB	abolished aggregation
DBS0237142	gpaB-/ [act15]: gpaB(N74D)	gpaB	decreased cAMP-induced cGMP pulse | decreased activation of adenylate cyclase | decreased chemotaxis rate | abolished aggregation | decreased cAMP-induced cAMP pulse
DBS0237143	gpaB-/ [act15]: gpaB(R64G)	gpaB	decreased chemotaxis rate | abolished aggregation
DBS0237144	gpaB-/ [act15]: gpaB(S155P)	gpaB	decreased chemotaxis rate | abolished aggregation
DBS0236097	gpaB-/ [gpaA]: gpaB	gpaB	abolished aggregation
DBS0236099	gpaB-/ [gpaB]: gpaB	gpaB	wild type
DBS0266944	gpaD-/ [act15]: gpaB	gpaB | gpaD	decreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266946	gpaD-/ [act15]: gpaB(1-345): gpaD(337-345)	gpaB | gpaD	decreased accumulation of cGMP | aberrant fruiting body morphology
DBS0266943	gpaD-/ [act15]: gpaD	gpaD	wild type
DBS0266945	gpaD-/ [act15]: gpaE	gpaD | gpaE	decreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266947	gpaD-/ [act15]: gpaE(1-339): gpaD(337-345)	gpaD | gpaE	decreased accumulation of cGMP | decreased chemotaxis to folate | aberrant fruiting body morphology
DBS0266941	gpaE-/ [act15]: gpaE	gpaE	precocious tip formation
DBS0266948	gpaE-/ [act15]: gpaE(1-339): gpaD(337-345)	gpaD | gpaE	precocious tip formation
DBS0304815	grlA-/ [act15]: grlA: GFP	grlA	aberrant tip formation
DBS0238866	grlJ-/ [act15]: grlJ: GFP	grlJ	wild type
DBS0238687	grpA-/ [act15]: grpA-FLAG	grpA	wild type
DBS0236152	hcpAΔC-GFP	hcpA	decreased growth rate in suspension | abolished growth on bacterial plates
DBS0252702	icmA-/ [act15]: TAP: YFP: rasG	icmA-1 | icmA-2 | rasG	abolished C-terminal protein amino acid methylation
DBS0238521	icpA-/ [act15]: GFP: icpA(1-1013)	icpA	aberrant protein localization
DBS0236493	krsA-/ [act15]: GFP: krsA	krsA	wild type
DBS0238721	krsA-/ [act15]: GFP: krsA	krsA	wild type
DBS0238722	krsA-/ [act15]: GFP: krsA(K49R)	krsA	aberrant streaming
DBS0238723	krsA-/ [act15]: GFP: krsA(T173A)	krsA	abolished streaming
DBS0238725	krsA-/ [act15]: GFP: krsA(deltaC)	krsA	aberrant streaming
DBS0238724	krsA-/ [act15]: GFP: krsA(deltaKinase)	krsA	abolished streaming
DBS0238726	krsA-/ [act15]: GFP: krsA(deltaNS)	krsA	abolished streaming
DBS0238109	mekA-/ ppp4C-/ [act15]: FLAG: pppC	ppp4c	decreased aggregate size | precocious development
DBS0266674	mhcA-/ [act15]: GFP: abpC(9-148)	abpC | mhcA	decreased uropod retraction | decreased pseudopod retraction
DBS0266675	mhcA-/ [act15]: GFP: mhcA(E476K)	mhcA	decreased pseudopod retraction
DBS0236548	mhcA-/ [act15]: GFP: pats1(2087-2351)	mhcA | pats1	aberrant cytokinesis
DBS0236549	mhcA-/ [act15]: limE(1-145): GFP	limE | mhcA	increased F-actin polymerization
DBS0238158	mhcA-/ [act15]: mhcA(81-2116)	mhcA	decreased growth rate | development arrests at tipped mound stage
DBS0236550	mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A)	mhcA	decreased filopodium formation
DBS0236551	mhcA-/ [act15]: mhcA(T1823D/ T1833D/ T2029D)	mhcA	increased filopodium formation
DBS0238157	mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R689H)	mhcA	decreased actin filament sliding
DBS0236557	mhkA-/ [act15]: mhkA	mhkA	decreased growth rate in suspension | development arrests at mound stage | aberrant cytokinesis | decreased myosin II assembly
DBS0238058	mlcE-/ [act15]: myc: mlcE	mlcE	wild type
DBS0266904	mpl1-/ [act15]: flag: mpl1	mpl1	wild type
DBS0266889	myoI-/ [act15]: GFP: myoI	myoI	wild type
DBS0266890	myoI-/ [act15]: GFP: myoI(809-1154)	myoI	decreased phagocytosis
DBS0237617	myoI-/ [act15]: gbpD	gbpD | myoI	increased pseudopod formation | increased cell-substrate adhesion | aberrant cell morphology
DBS0349846	myoK-/ [act15]: YFP: myoK(1-121: 262-858)	myoK	decreased phagocytosis
DBS0349850	myoK-/ [act15]: myoK	myoK	increased phagocytosis
DBS0349854	myoK-/ [act15]: pakB(1-337: 563-852)	myoK | pakB	wild type
DBS0236611	noxA-/ [act15]: noxA: myc2	noxA	aberrant fruiting body morphology
DBS0236702	nxnA-/ [act15]: GFP: nxnB	nxnA | nxnB	development arrests at mound stage
DBS0238362	p2xA-/ [act15]: p2xA: GFP	p2xA	wild type
DBS0236747	pefB-/ noxA-/ [act15]: pefB	noxA | pefB	aberrant development
DBS0304869	phg1A-/ [act15]: phg1a(1-276): phg1b(221-587)	phg1a | phg1b	decreased phagocytosis
DBS0304868	phg1A-/ [act15]: phg1b	phg1a | phg1b	increased secretion of lysosomal enzyme | decreased cell-substrate adhesion | decreased phagocytosis
DBS0304870	phg1A-/ [act15]: phg1b(1-220): phg1a(277-642)	phg1a | phg1b	decreased phagocytosis
DBS0237615	phg2-/ [act15]: gbpD	gbpD | phg2	increased pseudopod formation | aberrant cell morphology | abolished chemotaxis to cAMP
DBS0267125	plc-/ [OE]: dagA(PH): GFP/ [OE]: plc	dagA | plc	increased CRAC localization to the plasma membrane | decreased chemotaxis to cAMP | aberrant protein localization
DBS0236797	pldB-/ [act15]: pldB: GFP	pldB	abolished aggregation
DBS0236825	ppk1-/ [act15]: ppk1	ppk1	wild type
DBS0238110	ppp4C-/ [act15]: smkA	ppp4c | smkA	development arrests at mound stage | delayed development
DBS0238034	proC-/ [unk]: FLAG: proC	proC	wild type
DBS0302356	psrA-/ [act15]: FLAG: gskA	gskA | psrA	increased protein kinase activation
DBS0302357	psrA-/ [act15]: gskA(K84M/ K85M)	gskA | psrA	decreased culmination | decreased gene expression | delayed development
DBS0236831	pten-/ [act15]: GFP: pten-	pten	wild type
DBS0237191	racC-/ [act15]: CFP: racC	racC	increased chemoattractant-mediated F-actin polymerization
DBS0237614	rasC-/ [act15]: gbpD	gbpD | rasC	increased cell-substrate adhesion | aberrant cell morphology
DBS0266697	rasC-/ rasG-/ [act15]: carA	carA-1 | carA-2 | rasC | rasG	abolished activation of Rap GTPase activity | abolished growth | decreased growth rate | abolished protein kinase B activation | decreased activation of adenylate cyclase | abolished cAMP-induced cGMP pulse | abolished chemotaxis to cAMP
DBS0236859	rasD(G12T)	rasD	development arrests at mound stage | development arrests at tipped mound stage
DBS0236864	rasG-/ [rasG]: rasB	rasB | rasG	decreased growth rate in suspension
DBS0235706	regA-/ [act15]: dhkK(D1125N)	dhkK | regA	precocious development | aberrant fruiting body morphology
DBS0236976	talA-	talA	decreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology
DBS0304585	talA-/ [act15]: FLAG: talB	talA | talB	decreased cell-substrate adhesion
DBS0237616	talA-/ [act15]: gbpD	gbpD | talA	increased pseudopod formation | increased cell-substrate adhesion | aberrant cell morphology
DBS0238395	talA-/ [act15]: rapA(G12V)	rapA | talA	increased cell-substrate adhesion
DBS0304582	talA-/ talB-/ [act15]: FLAG: talB	talA | talB	wild type
DBS0304586	talB-/ [act15]: talA: GFP	talA | talB	aberrant fruiting body morphology
DBS0302383	tsuA-/ [unk]: tsuA(1-1774): YFP	tsuA	abolished localization of protein to the microtubule organizing center | decreased aggregate size | abolished localization of protein to microtubules | decreased fruiting body size
DBS0302385	tsuA-/ [unk]: tsuA(1-260): YFP	tsuA	abolished localization of protein to the microtubule organizing center | abolished localization of protein to microtubules | decreased aggregate size | decreased fruiting body size
DBS0302384	tsuA-/ [unk]: tsuA(1774-2247): YFP	tsuA	abolished localization of protein to the microtubule organizing center | abolished localization of protein to microtubules | decreased aggregate size | decreased fruiting body size
DBS0302382	tsuA-/ [unk]: tsuA(K34R): YFP	tsuA	decreased aggregate size | decreased fruiting body size
DBS0237033	vasP-/ [act15]: GFP: vasP(1-264/ 285-380)	vasP	abolished filopodium formation
DBS0237836	vasP-/ [act15]: YFP: wipA	vasP | wipA	decreased filopodium formation
DBS0237842	vasP-/ [act15]: YFP: wipA/ [act15]: vasP: FLAG	vasP | wipA	increased filopodium formation
DBS0237040	vasP-/ [act15]: vasP	vasP	decreased filopodium formation
DBS0237840	vasP-/ [act15]: vasP	vasP	increased filopodium formation | increased basal F-actin level
DBS0237037	vasP-/ [act15]: vasP(1-110: 231-380)	vasP	increased basal F-actin level | aberrant cytokinesis | decreased filopodium formation
DBS0237038	vasP-/ [act15]: vasP(1-228)	vasP	decreased filopodium formation
DBS0237039	vasP-/ [act15]: vasP(111-380)	vasP	increased filopodium formation | increased basal F-actin level
DBS0237812	wasA1-/ [tet]: YFP: wasA2/ [act15]: wasA	wasA	increased F-actin polymerization at the leading edge
DBS0237811	wasA1-/ [tet]: YFP: wasA2/ [act15]: wasA(Y33A/ W39A/ F90A/ F91A)	wasA	decreased F-actin polymerization | decreased F-actin polymerization at the leading edge
DBS0237820	wasA1-/ [tet]: YFP: wasA2/ [act15]: wipA	wasA | wipA	abolished chemotaxis
DBS0237091	yakA-/ [crlA]: crlA	crlA | yakA	abolished growth

Last updated January 28, 2012

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